Protein Alignment CG8475 and Phka1

DIOPT Version :9

• Sequence 1: NP_001260230.1
• Gene: CG8475 / 34114
• FlyBaseID: FBgn0031995
• Length: 1098
• Species: Drosophila melanogaster
• Sequence 2: NP_032858.2
• Gene: Phka1 / 18679
• MGIID: 97576
• Length: 1241
• Species: Mus musculus
• Alignment Length: 1252
• Identity: 377/1252 - (30%)
• Similarity: 590/1252 - (47%)
• Gaps: 263/1252 - (21%)

  Fly    50 QLDIYYGIVKRQLLRYQSPITGLFPVMSTDQVVGSVRDSVYCASAVWSLYQAYRR---IDDDRGK 111
            :||.|..:|.:.:|.:|:|:|||.|. |.||....|||:||...|||.|..|||:   .|:|:.|
Mouse    10 RLDGYARLVHQTILCHQNPVTGLLPA-SYDQKDAWVRDNVYSILAVWGLGLAYRKNADRDEDKAK 73

  Fly   112 SYELGQSTVKCMRGILECWVKQASRVELFKQRQSNQHALHSKFQLHTGEKIYPDEFYNHLQIDCV 176
            :|||.||.||.|||:|.|.::|..:||.||..||.:.:||:|:...|...:..|:.:.|||:|..
Mouse    74 AYELEQSVVKLMRGLLHCMIRQVDKVESFKYSQSTKDSLHAKYNTKTCATVVGDDQWGHLQLDAT 138

  Fly   177 SLYLLFLVQMITSGLQIIYTHDEVAFVQNLVYYVERAYRTPDFGMWERGSKYNNGTPEIHASSIG 241
            |:|||||.||..|||.||::.|||.|:||||:|:|.||:|.|||:||||.|.|.|..|::|||:|
Mouse   139 SVYLLFLAQMTASGLHIIHSLDEVNFIQNLVFYIEAAYKTADFGIWERGDKTNQGISELNASSVG 203

  Fly   242 MAKSALEAINGCNLFGEKGASWSVVYVDIDAHNRNRSIFETMLPRESSSKGVDASLLLTLSFPAF 306
            |||:||||::..:|||.||...||::|..|.....:||..::|||.|:||.||||||..:|||||
Mouse   204 MAKAALEALDELDLFGVKGGPQSVIHVLADEVQHCQSILNSLLPRASTSKEVDASLLSVVSFPAF 268

  Fly   307 ASHEDRLVEQTKQNVVNRLRCKMGFKRFTRDGFLSKNEDKSRRYYHSGELKEFEGLECEWPLFFI 371
            |..:..|||.|||.::.:|:.:.|..||.|||:.:..||.:|.||...|||.||.:|||||||:.
Mouse   269 AVEDSHLVELTKQEIITKLQGRYGCCRFLRDGYKTPKEDPNRLYYEPAELKLFENIECEWPLFWT 333

  Fly   372 AMIIDGVFKNNNEQIEEFQNDLRRCLRTDVNGDPVVTMYYA--PDG-DGSYM------RAPSQSL 427
            ..|:||:|..|.||::|::..|...|....||.|::...|:  ||. |..|.      |.|...|
Mouse   334 YFILDGIFSGNVEQVQEYREALDAVLIKGKNGVPLLPELYSVPPDRVDEEYQNPHTVDRVPMGKL 398

  Fly   428 -FLWGQSFFIIAQLLTAGLLHINELDPIRRYLPSYNRPRRAGRYSAFQAKPGTGTATDLVVQIVL 491
             .:||||.:|:..|:..|.|...|:||:.|...:..:|                   |:|||:.:
Mouse   399 PHMWGQSLYILGSLMAEGFLAPGEIDPLNRRFSTVPKP-------------------DVVVQVSI 444

  Fly   492 IAESMRLQAMMATYGIQTQTPHEVEPVQIWSSTELIKVYQHLGVNNKVGLSGRPCRPVGSLGTSK 556
            :||:..::|::...||..:|..||.|:::..:..|..:|..||.|:::.|||||.|.:|.|||||
Mouse   445 LAETEEIKAILKDKGIDVETIAEVYPIRVQPARILSHIYSSLGCNSRMKLSGRPYRLMGVLGTSK 509

  Fly   557 VYRICGMTVLCYPLIFEVSDFYLYRDMALLIDDIKTELQFVGKYWRLSGRPTVCLLIREEHMRDP 621
            :|.|........|...:...|||..|..::::.::|:|.::...||::|:||:...|....:.:.
Mouse   510 LYDIRKTIFTFTPQFIDQQQFYLALDNQMIVEMLRTDLSYLCSRWRMTGQPTITFPISHTMLDED 574

  Fly   622 QFKEMLDLLAMLKK---GYCDGMKVRIGRLQNLISSSCIEHLDFMNQS----------------- 666
            .......:||.|:|   ||..|.:::.|:|...:::||..||.||:..
Mouse   575 GTSLNSSILAALRKMQDGYFGGARIQTGKLSEFLTTSCCTHLSFMDPGPEGKLYSEDYDEDYEDD 639

  Fly   667 ----------DLTDNENAFSQIN------------------------------------------ 679
                      |.|.|.....::.
Mouse   640 LDSGNWMDSYDSTSNARCGDEVARYLDRLLAHTVPHPKLAPTSRKGGLDRFRAAVQTTCDLMSLV 704

  Fly   680 -----------HEYIGYQ---------SLTDVPKALTYVEEKISVAHFDTKPTPD---------I 715
                       |.|:..:         :|.|.|::..  :.::...|.:.....|         :
Mouse   705 AKAKELHIQNVHMYLPTKLFQPSRPSLNLLDSPESPQ--DSQVPSVHVEVHLPRDQSGEVDFQSL 767

  Fly   716 INALRSTDSIYCLCQLWGIILNREGPH-----FEVNGLNVNTALTQLYHRAGSLRYWRAVRYCSS 775
            ::.|:.|.|:.....:..::.:.:||.     :|..|..|...|::||.:.|.:|:|..:||.|.
Mouse   768 VSQLKETSSLQEQADILYMLYSMKGPDWNTELYEEGGATVRELLSELYVKVGEIRHWGLIRYISG 832

  Fly   776 LLHHIVDSISPFITTVLVNGKELTVGIIGQ-KETVFDKPMTPAEIQNVMYTSVQPYDVIQAVLQQ 839
            :|...|:::....|.:|...|.||||:..: :|.....|: |.|....:.......|:..:.|.|
Mouse   833 ILRKKVEALDEACTDLLSYQKHLTVGLPPEPREKTISAPL-PYEALTKLIDEASEGDMSISTLTQ 896

  Fly   840 EVVLYCGRLIATNPSMFRGILKIRIGWVLEAMRI----YLQISGQQSID-VDNLSPFQVRILLQK 899
            |:::|....:.|.|.:|..:.::|||.:::.|..    .|:.|.:::.: :.||||..::.||..
Mouse   897 EIMVYLAMYMRTQPGLFAEMFRLRIGLIIQVMATELAHSLRCSAEEATEGLMNLSPSAMKNLLHH 961

  Fly   900 VLTVSEWAVE---------------------------EKLTTLQ--------------------- 916
            :|:..|:.||                           |:...:|
Mouse   962 ILSGKEFGVERSVRPTDSNVSPAISIHEIGAVGATKTERTGIMQLKSEIKQVEFRRLSVSMESQT 1026

  Fly   917 ------------------------------------------------RRQLEGCLCRVPKHFYN 933
                                                            ||:|:|.|.|||..||.
Mouse  1027 SGGHPSGVDLMSPSFLSPAACIAASSGSFPTVCDHQTSKDSRQGQWQRRRRLDGALNRVPIGFYQ 1091

  Fly   934 KIWEILQRTPQGILTQGHHLPATPTLTNMSRGELTFNLLVEETLICIDRPERRQITVELLCIVAT 998
            |:|:|||:. .|:..:|..||:: |...|:.||:.|::.||..|..:.:||.||:.||.: :|.|
Mouse  1092 KVWKILQKC-HGLSVEGFVLPSS-TTREMTPGEIKFSVHVESVLNRVPQPEYRQLLVEAI-LVLT 1153

  Fly   999 ILNRNPELHFKQALDLDGILA-EAFAMYCKDNNIQHQPKPEHEQT--KNEDLKAFYSLPYSE--- 1057
            :| .:.|:|     .:..|:| |.......|..:|.|.....:.|  ..:......:|.|..
Mouse  1154 ML-ADIEIH-----SIGSIIAVEKIVHIANDLFLQEQKTLGADDTMLAKDPASGICTLLYDSAPS 1212

  Fly  1058 ----TTGYLARAAVNKV 1070
                |..||::||...|
Mouse  1213 GRFGTMTYLSKAAATYV 1229

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG8475	NP_001260230.1	Glyco_hydro_15	49..>468	CDD:279112	198/430 (46%)
		Glyco_hydro_15	<739..866	CDD:279112	37/132 (28%)
Phka1	NP_032858.2	Glyco_hydro_15	8..>439	CDD:279112	199/448 (44%)
		Glyco_hydro_15	<805..923	CDD:279112	33/118 (28%)
		Calmodulin-binding. /evidence=ECO:0000255	811..841		11/29 (38%)
		Calmodulin-binding. /evidence=ECO:0000255	1064..1104		16/40 (40%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3635
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D38956at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_101837
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	5	4.720