Protein Alignment Piezo and AT2G48060

DIOPT Version :9

• Sequence 1: NP_001303314.1
• Gene: Piezo / 34112
• FlyBaseID: FBgn0264953
• Length: 2973
• Species: Drosophila melanogaster
• Sequence 2: NP_001323909.1
• Gene: AT2G48060 / 819418
• AraportID: AT2G48060
• Length: 2485
• Species: Arabidopsis thaliana
• Alignment Length: 3131
• Identity: 589/3131 - (18%)
• Similarity: 1046/3131 - (33%)
• Gaps: 1064/3131 - (33%)

  Fly   216 FCLATLFFAAVL-RPSVPGGFYFLIFLL------------SGTYWATCQTLQRGFALLLRCVMVV 267
            |.|.:|..||.| ..||......:.|||            ...:|.........||:.|..|:.:
plant     8 FLLPSLLLAAALINWSVISFLDLIAFLLVHYIAPEIGYRFQRRHWLLWPIFIFSFAVFLAQVVYL 72

  Fly   268 LVLHSLSIVSYQTP---WMQSHLNHTTLTARLIGLEPLIESYCSPDIRVFLYNNKLSLDSYLNPF 329
            ::..:|. ..:.||   ||           |:||.                    :.|.|:.||.
plant    73 VIWAALG-QDWDTPDTGWM-----------RVIGF--------------------MILKSWRNPT 105

  Fly   330 ALFFAYFALALTTKHLIKPRLVRQSTRKARTPQPLESGSSVAPSVTQRGNDMQLESMEQRSEQEN 394
            .::|    |||                     |.|.|..::|...:.|..         .:...:
plant   106 VMYF----LAL---------------------QLLTSLVALADIYSSRFG---------FARWRD 136

  Fly   395 TTTSILDQISYGFVSVGGFIYQNSYIFTNILMMAWSIVYHSWLT---FVLLLSANVLWMIPNQRK 456
            |..|....|   |..:|..:...|.:....:.:|..|...||::   |:...:..|.|.:.:...
plant   137 TWWSHFSGI---FEHLGSHLRVASCLLLPAVQLAVGICNPSWVSLPFFIGSCAGLVDWSLTSNVS 198

  Fly   457 AMMRSSPFIVLYAEALLIAQYIYGMDLNNEELPTSVPTAGINLQQIGFERPIENQMRPCVPLIVK 521
            .:.|....:.:||...::..|:|.:.:|..::...: .:.|.|.:|..|..        .|.|..
plant   199 GLFRWWRVLYIYAGFNIVLLYLYQLPINFSDMIRWI-ASFIGLFRISLETE--------GPDICS 254

  Fly   522 TAFVLMFWVTSRQFFKEKRD-----RRRDSTLADFIAPLQITVGSAGSSYLINDG----KKTSKF 577
            ..|:::|::.......:..|     ...::.||:.:.|.:.       |:.|.:.    :.|:..
plant   255 GLFLVLFYIMLSYVRSDLEDMDFIMSTSENNLAERLLPPKY-------SFFIRESRAGVRHTNVL 312

  Fly   578 LKKAGDVIKNLLVRLWIWLLVLVIFLCAITGENMTGFRICYMALFLFFLLVFQSSSKAWVKIMYG 642
            |:  |.|.|...:..:.:...:.:|.       ::.:...:.:|..|.||.:..      .|:|.
plant   313 LR--GAVFKTFSINFFTYGFPVSLFA-------LSFWSFHFASLCAFGLLAYVG------YIIYA 362

  Fly   643 FWLFLIFYAMSILILIY-------TYQFDKFDTYWSDYLNVSATLQKDIGLKRYQTKDLFL---- 696
            |......:.::.|:|::       ||.|:...::.:..:.....:.:.:||..|.....||
plant   363 FPSLFQLHRLNGLLLVFILLWAVSTYIFNVAFSFLNTKVGKDMQIWEMVGLWHYTIPGFFLLAQF 427

  Fly   697 ---------HLVSPTIIVILTVIQVHYFHKRFIASLQQQPLAGGSAQQKPTETTALEPAPSKRRG 752
                     :||:.::.:.|:.......::|             |..:...||..|..|.
plant   428 GLGMLVALGNLVNNSVFLYLSEESSRSSNER-------------SYVEADEETKVLVVAT----- 474

  Fly   753 SAGSLRKSQGPSAEA-------APG--------------ATTDFETSVR---------------- 780
            .|..|||.......|       .||              .:.:....:|
plant   475 IAWGLRKCSRAIMLALIFLIAMKPGFFHAVYVIFFLMYLLSHNINRKIRKSLILLCEVHFALLYI 539

  Fly   781 ---DLVRISFRKIKNKSEYIFKNF----KDVFWRFLELHIMKAVYIAAFVCSVSEVCVLH----- 833
               |||..|.::..:.|..:....    .:..|.|||        ||...|    .|.:|
plant   540 LEIDLVSNSLKQEGSASREVLFQLGLLRSESSWDFLE--------IALLAC----FCAIHNHGFE 592

  Fly   834 IIF-------------VGFCVLGATSRKAVQVVISRLISFIVTVIVLSKMIYQIEYLSHSQHNVV 885
            ::|             :||.:|.|...|:|      |:|           :|.....|:||.|..
plant   593 VLFSFSAIVRHTPSPPIGFSILKAGLNKSV------LLS-----------VYSSPSSSYSQDNTT 640

  Fly   886 CSDNRTANNAEWIGLTKADKVTGGLMSLLRTYIIYMVIVTMHAVISLRQLQMRVKIGALNAPPTK 950
             .:...|:....||..        .:|:.|:...|:..:|:  :||:                 .
plant   641 -YERHIASFLSAIGQK--------FLSMYRSCGTYIAFITI--LISV-----------------Y 677

  Fly   951 LLFPNIIRADAEKDLVGLVKYLLNFGFYKFGIEISLIALVSTITYRQDIVAVVYALWLVVLLLLR 1015
            |:.||.:                :||:        :..|:..||.||........||..:
plant   678 LVKPNYV----------------SFGY--------IFLLLLWITGRQLFEETKRRLWFPL----- 713

  Fly  1016 RSQCAKIWGVFQAFFAISILTQYIVLVGLPPSSCLVFPWDEGPFGEGIQRWAMLPG------ALH 1074
                 |.:.|. .|..|..|:.::                      .:|.|  |.|      .|.
plant   714 -----KAYAVL-VFMFIYCLSSFV----------------------SLQLW--LSGFIDLYFYLG 748

  Fly  1075 FNHVPKLIFD----FIVLVILNRQKSIFCIEQRYASNDDYPGGSNRSVIADIAQLGRVPFDNPTH 1135
            :|....|:.:    ..||:::    .::..|:|.:.:
plant   749 YNSKAPLLDNVWESLAVLIVM----QLYSYERRQSGH---------------------------- 781

  Fly  1136 DFCSYIRNYSDILKNGVLCGFYWFTLAVVFLAGTNIADLLALGYLIGAFIFLWQGSD------FY 1194
                ||...|.:|..||. ||:...||                         |.|..      ||
plant   782 ----YIPGQSSLLHPGVF-GFFERFLA-------------------------WHGQKILFAALFY 816

  Fly  1195 --LRPIHTIIFRWKWLLAFNVANILIK-TSFQMAGCLFMTQLTKDCCWLVHMLGITCTSNVLTEQ 1256
              |.||.  :|.:.:||...:.....| :|......|..|.......:|..:.|:        :.
plant   817 ASLSPIS--VFGFVYLLGLVICTTFPKSSSIPSKSFLIYTGFLVSAEYLFQLWGM--------QA 871

  Fly  1257 IMLPEE--AELALKPGECPKITHQVVLLWDTICFAFIIFQLRIFKSHYFCHIITDTKANNILASR 1319
            .|.|.:  |||:...|                        ||:::..::
plant   872 QMFPGQKYAELSFYLG------------------------LRVYEPGFW---------------- 896

  Fly  1320 GADIIESLRHKQIAHRHDHEKQVLHKIKRKMERIRA--TQQKMLRPLDKQTHFDGRRTPSEHAMS 1382
              .|...||.|.:.                   :.|  .|..:.|.|::.:..    |..:....
plant   897 --GIESGLRGKVLV-------------------VAACTLQYNVFRWLERTSGL----TVIKGKYE 936

  Fly  1383 DVAPLVHNSSFTSCQGSGYLTPDEHSSATSGTSSPARASILSSSGGSVESVDSADAAVIIEPEIN 1447
            :..||     |.|.:.:                   .||:.||:|.:..|
plant   937 EPCPL-----FVSAEDT-------------------TASVSSSNGENPSS--------------- 962

  Fly  1448 VMPCDEITDYVDVQSVSEEETTVAMPKKDLSCQSKECVFKSPEPSKPTTPSTDALSTLLTEGFLE 1512
                   ||:..:.....|.|:.:.|            |.||..::..             |||.
plant   963 -------TDHASISMKQGEATSNSWP------------FFSPRGNQGA-------------GFLH 995

  Fly  1513 PKRISLGLAPPELSPPVGMQCLAPPLAAYATAMASSAASSVLS-TNLTPNLRREHRRQSSTNAAV 1576
            ||                            |..:.|.:|...| .:...:::..||
plant   996 PK----------------------------TGGSESGSSRKFSFGHFWGSIKESHR--------- 1023

  Fly  1577 SWNETVSIKRSPMKKQMSADKEEVVTMRHKSLHRRH-----QSMGN-------------ASYSLD 1623
             ||.         ::.::..||...|  .|:|.:.:     ::|.|             ||::|.
plant  1024 -WNR---------RRILALKKERFET--QKNLLKIYLKFWIENMFNLYGLEINMIALLLASFALL 1076

  Fly  1624 EASQS-----------QRKRLSSNLSG----------ARDEAALRSAQRPHSWGPVGTSSYME-- 1665
            .|...           .|:|:...|..          |.:..|..::..|....|..||.:..
plant  1077 NAISMVYIALLAACVLLRRRVIQKLWPVVVFLFASILAIEYVATWNSFLPSDQAPSETSVHCHDC 1141

  Fly  1666 -SLMCAFYE-------PALLHGPSTRAGDYYMFEEMDDKFELDLIHDEIDFLEEENITESEMKMQ 1722
             |:...:::       ...:..|.|....:.:|.....|...|.|..     ..|:.|..:||.|
plant  1142 WSIAALYFKFCRECWLGVRVDDPRTLISYFVVFMLACFKLRADHISS-----FSESSTYHQMKSQ 1201

  Fly  1723 RRKTLYDVWKDLNDAEYRRHF----YMRERSYA----------------------------SEPG 1755
            |:.:.  ||:||: .|.:..:    |:|...|.                            :...
plant  1202 RKNSF--VWRDLS-FETKSMWTVLDYLRLYCYVHLLDVVLILILITGTLEYDILHLGYLAFALVF 1263

  Fly  1756 SRILLKLDDEKEKI-------------------GPDLGLASDHD-EDDDTI-------ECDLGMR 1793
            :|:.|::..:|.||                   .|.:|..:|.. |..|.|       :.|.|.|
plant  1264 ARMRLEILKKKNKIFRFLRVYNFVLIIFSLAYQSPFVGNFNDGKCETVDYIYEVIGFYKYDYGFR 1328

  Fly  1794 ---TSTLSEPLDFGRRSQTLLEVKSKDAPTGEFPSTSKGISKERDAATASSSASPAPTRDVGDLP 1855
               .|.|.|.:.|     .|:.::|....:.||...|:.:..|:..|
plant  1329 ITARSALVEIIIF-----MLVSLQSYMFSSQEFDYVSRYLEAEQIGA------------------ 1370

  Fly  1856 VIPPPSTGLGREQTSKETSDSKSKMEVDSGEVTAKDSDEDFDTNPIIRLLEGFLVTLTIRLNRFS 1920
                    :.|||..|....::...::...|      ::....|..:..::..::.|.::|:|.:
plant  1371 --------IVREQEKKAARKTEQLQQIREAE------EKKRQRNLQVEKMKSEMLNLRVQLHRMN 1421

  Fly  1921 RNYRFVNRILAGEKKTLKESSSLNRLGLSSAAA-----MFHFLKSNLESDESEPPASSSTPRRVV 1980
            .:..|  .:.:...:.|:...|...:..|.||:     :.|..:.....::|:.|..:
plant  1422 SDSNF--GVASPRTEGLRRRKSPYLIPDSGAASPEIDGVVHRKEEQPIDEDSQYPFEA------- 1477

  Fly  1981 IAPPNATEHSDPTSTT---LNTNTTTTPLSPPEPLQPLQPLQPNTTSTPQQQHQHIRAAEEIIEL 2042
                    |..|.|||   |::...:...||.|..:..|.|  :..|..:::.|.....|..:..
plant  1478 --------HEFPVSTTPEALDSPEYSFGASPCEITEVQQDL--DVMSMERERKQKSEGKENPLIS 1532

  Fly  2043 PVDTV-DGVAH----RKQSINS-------SPPAKGTMLSRKSDCGLPEIRIKAPSIERGAHYYHN 2095
            .|..: |||:.    ..|::|:       ||....|......|   .|:..:..|.:|
plant  1533 AVQLIGDGVSQVQFIGNQAVNNLVNFLNISPENSDTNEQSSVD---DEVYDEMESQKR------- 1587

  Fly  2096 HHSGGGSGSLSKHWSYEQVDSAGEFNLEEENFAQRDHHIIVEVLISSWYALLANTDLICYIVVFI 2160
                       ||..:|:..|     |:.:..:......|..:....|..:.:|.|::||....|
plant  1588 -----------KHTPFERSTS-----LQSDRSSDGTSFQIGRIFRHIWSRMQSNNDIVCYCCFII 1636

  Fly  2161 NQVVNASLISLPLPIMVFLWGTLSLPRPTKTFWVTLIAYTQAIVLIKCIFQFKLIWSN------- 2218
            ..:.|.||:|:.....:||:.......||..|||.::.||:..:|::.::|..:....
plant  1637 AFLWNFSLLSMVYLAALFLYALCVHTGPTHIFWVIMLMYTEIYILLQYLYQIIIQHCGLSIDAPL 1701

  Fly  2219 YHQL--PNQPLTPAKIFGVENKAHYAIYDLILLLVLFLHRYLLKSQGLWKSGYKDTDNQFT-KPT 2280
            .|:|  |.|.:          |:.:.:..|.|.|:...  .|::|....|.|.......|| :..
plant  1702 LHELGFPTQRI----------KSSFVVSSLPLFLIYIF--TLIQSSITVKDGDWVPSADFTSRRN 1754

  Fly  2281 ASIDERD------------------DSDNL-----------------SQPDSRQLNDDA------ 2304
            |...::|                  ||..|                 |.|...|:..|.
plant  1755 ARGSQKDLTRIRLSQRILDVFKKLRDSAKLVIRSIYRYWISLTRGAESPPYFVQVTMDVHMWPED 1819

  Fly  2305 -----------AQKLSLQVSQASLPGSPEF----SKTGINQLERT-------------KYTS--- 2338
                       .|.|.|..::....|:|:.    |:..:..:||:             :|.|
plant  1820 GIQPERVECRMNQLLRLVHNERCEKGNPDLCPYSSRVHVQSIERSTETPNEALVVLEVEYASPTN 1884

  Fly  2339 --SLYKFFFSLVHKSRLA-------------------------------TDVYALMFLCDFVNFF 2370
              |..:::.||...|.:|                               ||:||.:|..|.:.||
plant  1885 GCSSAEWYKSLTPASDVAKEIRKAQHSGLGEGTGFPYPILSVIGGGKRDTDLYAYIFGADLIVFF 1949

  Fly  2371 VLLFGFTAFGTQQTESDEGVQTYLAENKVPIPFLIMLLVQFLLIVIDRALYLRKALVNKIIFHFF 2435
            ::...:.:....::|.   :..|..|::.|..|:|:|:|.|.|||:||.:||......|::::.|
plant  1950 LVAIFYQSVIKNKSEF---IDVYQLEDQFPFDFVIILMVIFFLIVVDRVIYLCSFATGKVVYYLF 2011

  Fly  2436 SVI----GIHIWMFFVVPAVTERTFNSLAPPIIFYVIKCFYMLLSSYQIKSGYPKR--ILGNFFT 2494
            |:|    .:..:.:.:.|  |::....||..||| :.|...:.|.:.||:.|.|.:  :...|.|
plant  2012 SLILFTYAVTEYAWSIYP--TQQHAAGLALRIIF-LAKAMSLALQAIQIRYGLPHKSTLYRQFLT 2073

  Fly  2495 KGFSMVNMIAFKVYMQIPFLYELRTILDWVCIDSTMTIFDWLKMEDIFSNIYLIRCTRQSETDFP 2559
            ...|.:|...:::|..:|||||||.:|||.|..:::|::||||:||:.:::||::|      |..
plant  2074 SEVSRINYYGYRLYRALPFLYELRCVLDWSCTATSLTMYDWLKLEDVNASLYLVKC------DTV 2132

  Fly  2560 AMRA-----QKKASLSKLIMGGTIVLLIVICIWGPLCLFALGNAVGTSNVPFHVSLSI---RIGP 2616
            ..||     :|:..::|...|..:..:::..||.|:.:::.||....:|.....|:.|   .:|.
plant  2133 LNRATHKHGEKQTKMTKCCNGICLFFILLCVIWAPMLMYSSGNPTNIANPIKDASVQIDLKTVGG 2197

  Fly  2617 YDPIYTTNNYDSI----FEINPEMYSQMTNAYIKEKQALTFIAGYDATDVAAVRLAGNSPSLWNI 2677
            ...:|.|...:.|    .::..::.||            :|:..|:..|:..:....::..||.:
plant  2198 KLTLYQTTLCERISGDNIDLGLDLGSQ------------SFLPTYNKNDIQLICCQADASVLWLV 2250

  Fly  2678 APPDRQRLLNDLRNNHTLKARFSYSLTRKAPAKGLKENVGDEHAIS-LDESFEGRAALIHMLSET 2741
            ......|.:..|..:..:...|::.|.|..| || ||.|..|.::. ||            |.:.
plant  2251 PDTVVTRFIQSLDWDTDMDITFTWVLNRDRP-KG-KETVKYERSVDPLD------------LPKR 2301

  Fly  2742 HDVEPIYSNGTTNGTTPEVEEVVVIPGMIPKFIKVLNSGDAAVVSVLSPKHYDYRPLVIKMHRD- 2805
            .|::.:. ||:.:|..        :..:.|||.:|..|||..          .:.....::..|
plant  2302 SDIQMVL-NGSMDGFR--------VHNLYPKFFRVTGSGDVR----------SFEDQTDEVSADI 2347

  Fly  2806 --NETNGLWWEIRDYCNDTFYNETLSKFAYSNC--TSGIVMYTFNDKKFPSTF--SFLTAGGIIG 2864
              |..|..||.       :|:|...|: ..|.|  ..|.|....:::..|..|  ..|:...|.|
plant  2348 LINHANFKWWW-------SFHNLKASE-NISACEGMDGPVAIIMSEETPPQGFLGDTLSKFSIWG 2404

  Fly  2865 LYTTFVLLASRFMKSFIGGQNRKIMFEDLPYVDRVLQLCLDIYLVREALEFALEEDLFAKLLFLY 2929
            ||.||||...||::........:|.:|:||..||::.:|.|:|..|...|..:||.|:..|:.:|
plant  2405 LYITFVLAVGRFIRLQCSDLRMRIPYENLPSCDRLIAICEDLYAARAEGELGVEEVLYWTLVKIY 2469

  Fly  2930 RSPETLIKWTR 2940
            |||..|:::|:
plant  2470 RSPHMLLEYTK 2480

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Piezo	NP_001303314.1	PIEZO	1226..>1363	CDD:292539	18/140 (13%)
		Piezo_RRas_bdg	2511..2941	CDD:288978	118/450 (26%)
AT2G48060	NP_001323909.1	None

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	138	1.000	Domainoid score	I1571
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	294	1.000	Inparanoid score	I816
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0001637
OrthoInspector	1	1.000	-	-		otm3283
orthoMCL	1	0.900	-	-		OOG6_102664
Panther	1	1.100	-	-	O	PTHR13167
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X1528
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	8	8.050