Protein Alignment Rbsn-5 and rabs-5

DIOPT Version :9

• Sequence 1: NP_609186.1
• Gene: Rbsn-5 / 34110
• FlyBaseID: FBgn0261064
• Length: 505
• Species: Drosophila melanogaster
• Sequence 2: NP_001294172.1
• Gene: rabs-5 / 177603
• WormBaseID: WBGene00021538
• Length: 565
• Species: Caenorhabditis elegans
• Alignment Length: 567
• Identity: 147/567 - (25%)
• Similarity: 244/567 - (43%)
• Gaps: 123/567 - (21%)

  Fly    19 ILEGFLCPICRADLKSIDVLTDHFARQHAEEEDA------LKSFKDIFTKAKKKILNPFEDEKGA 77
            :.:||:||.|..|....:.|..|....|.||:.:      :.:.|..|.|||:.| ...:.:|
 Worm    17 VRQGFICPFCMEDFGEYERLICHVENDHPEEDSSDLAGMFVSNVKGFFDKAKRGI-QKLDAKK-- 78

  Fly    78 SVSSPAGSSSSAAGKNPNGNGDRNGPSNARSRLNVFNYMARQQPGAECSHFEYFQSIRNPRLERY 142
            |::..|.:..:...:......:|.........|.....:    ||...|....|.|.|...:...
 Worm    79 SIADLASNVETEFTETTEKLVERAPLPRIPKPLPPDEIL----PGTRRSKTREFLSTRELNINEV 139

  Fly   143 ASETNKLIIRLHRLLKDLPADS--VQRRQHEQQTVAWLDGSSVKLCPSCAKSFHIARRQHHCRLC 205
            |..||.|||||.||:...|.|.  |:|::.|::.|.|||.:....||.||..|.:.||:||||||
 Worm   140 AVRTNMLIIRLDRLINGGPKDKDPVKRKEFEREVVPWLDDAEAVCCPLCASRFGLTRRRHHCRLC 204

  Fly   206 GGIMCNDCSKFLPLEDAMQLASLSTTRSEPL---------------------------------- 236
            |.::|:.|||||..:.|..|    |:.|.||
 Worm   205 GRVLCHSCSKFLSFDTAKTL----TSSSNPLGDTHIIVEEPNTVENEQELLQPEENGRRSFFSLS 265

  Fly   237 ----------------------------------QQLHQHENAIRLCEHCLWLLDTRKDMH--ES 265
                                              |.|.:|   :|:|..||      :|:|  ||
 Worm   266 QKSMDKMKRAMAGAVQKVHSAATGEEIIAGALNEQDLSEH---MRVCNLCL------RDLHFRES 321

  Fly   266 RTCR---PLLVQVYEQIRQLQKEVTPDLDMYLKIINSLNEGDTIFTLADAGALRGKIGQVAEAMD 327
            :..:   |..||.|:.::.:.:||...:..|::::.||..|:::::......||.|..::.:::|
 Worm   322 QMDKKEPPEFVQQYDLMKVMIEEVKNLVPTYVRVVTSLKNGESVYSHKHGEELRSKCLEIQKSID 386

  Fly   328 MRSKRIL-AIFCEPGS-REEALKKAIRLGCIQAIK---ERMLSLPPLPEESH-IRQMQERRRME- 385
            ..||:|. ....:|.| :|:.|:|.|||..:||::   .:|.|||...|.|: |.:.:|||..:
 Worm   387 YVSKKIAEGANDKPNSAKEQQLRKNIRLYAVQALQGLIGQMESLPTAEECSNLIIKRKERRAKDF 451

  Fly   386 -----TEQRILTEQRMAMEAYERNNMAANQSNVGVPGPES---GSFAQGSDLQSLNNWSAPQAAS 442
                 |..::.:......|.:...|..::.|:.|  ||.|   |..|:.:||..:   ..|.:..
 Worm   452 ARVNRTVMKMSSSMPQLQEQHSHLNSTSSVSSFG--GPSSIDDGWSAEDNDLSRV---FEPSSIE 511

  Fly   443 KSSL--DDPLIEQINIIKGYIKQARQDMNFEVVETLELNLRELQREV 487
            ..::  |.||.||...::.::.||......:.::.||.||:|::.|:
 Worm   512 DDTIQTDHPLYEQREQLRKFLFQASATGKLDEMDILERNLKEIEEEM 558

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Rbsn-5	NP_609186.1	FYVE_RBNS5	174..259	CDD:277256	37/152 (24%)
		Rbsn	449..487	CDD:288341	11/37 (30%)
rabs-5	NP_001294172.1	zf-Di19	21..>47	CDD:368517	8/25 (32%)
		FYVE_like_SF	173..>218	CDD:333710	24/44 (55%)
		Rbsn	523..559	CDD:371544	10/36 (28%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160165730
Domainoid	1	1.000	55	1.000	Domainoid score	I7484
eggNOG	1	0.900	-	-		E1_KOG1842
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H41477
Inparanoid	1	1.050	134	1.000	Inparanoid score	I3151
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG49473
OrthoDB	1	1.010	-	-		D707099at2759
OrthoFinder	1	1.000	-	-		FOG0005770
OrthoInspector	1	1.000	-	-		oto20729
orthoMCL	1	0.900	-	-		OOG6_105165
Panther	1	1.100	-	-	LDO	PTHR13510
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R8149
SonicParanoid	1	1.000	-	-		X4165
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	16	15.800