Protein Alignment PAPLA1 and ddhd1a

DIOPT Version :9

• Sequence 1: NP_609185.1
• Gene: PAPLA1 / 34109
• FlyBaseID: FBgn0031990
• Length: 2016
• Species: Drosophila melanogaster
• Sequence 2: XP_005159001.1
• Gene: ddhd1a / 562868
• ZFINID: ZDB-GENE-111020-16
• Length: 825
• Species: Danio rerio
• Alignment Length: 834
• Identity: 199/834 - (23%)
• Similarity: 329/834 - (39%)
• Gaps: 218/834 - (26%)

  Fly  1320 TLAPAPTQTDRQSGDDLLQQHLGELPEDILRELRMASASSEKGQVATPPVA-------------- 1370
            |||......|..|||     ||......:...|..::.|     ..|.||:
Zfish    54 TLALRNPTRDALSGD-----HLDLSTTSVANYLHNSNTS-----YCTSPVSDCHGKALDIRKRSC 108

  Fly  1371 ---------IPYSPVVAHWFYKRSVDTKFIWTPFSHYDSALLE------TSLN------------ 1408
                     ....|....||||   :.|..|.||..:||..:|      |.||
Zfish   109 APRHRFEVVTELGPEEVRWFYK---EDKKTWKPFMGHDSLNIEIMYRRFTQLNPGGSVNQERFGE 170

  Fly  1409 ----------LDDSTLIIPVEGGRYDVNIKERTKTPVYW-EGKAIEVRRCSWFYKGVDSKYVPYT 1462
                      :|.....:.|.||.|:|:::.:...|||| :.:.|.|.|..||   .|:.:.|..
Zfish   171 DGAPLERRESVDAGVEAVCVRGGLYEVDVRSKECYPVYWNQQERIPVMRGQWF---TDATWAPVE 232

  Fly  1463 EDTAALLEAEYK---RSAETGEWHQKIMLA---NGEQVVFHGPTVIVHFLPQQNADTWGASTQGS 1521
            ||.:.|:|.|:.   |..:..:......||   :.:.|:.|.|...:.||.:.:....||.:...
Zfish   233 EDESELIEKEHLTCFRGQQIQDNFDTDALAKTVDRKDVLSHFPPFYLPFLFKWSGYQTGAKSHKR 297

  Fly  1522 MRPRVV------KRDLDDFTIEQ--------------------GESQ------------------ 1542
            .|.:.:      :..:|.:::::                    |.|:
Zfish   298 KRCQAIHSVQLSRSHVDWYSVDEVYLYSDATTSKIARTVTQKLGFSKASSSGTRLHRGYVEEASL 362

  Fly  1543 -----RVDHLLFMVHGIGSACDLKMRSVEEVVDDFRVIAQQLVQSHYKNSTDMGLVGRVEVLPIS 1602
                 ...|::|::||||...| |.|.::. ....|...:::.:.||...|:    ..||.||:.
Zfish   363 DDKPPNTTHIVFVIHGIGQKMD-KDRIIKN-TGMLREAVRKMEEKHYSEQTE----EHVEFLPVE 421

  Fly  1603 WHGHLHSEELGID-EKLKSITLESIPRLRNFTNDTLLDVLFYTSPKYCQKIMNTVADALNDVYLK 1666
            |.     .:|.:| :.::|||.:.:..||:..|.:.:|:::||||.|..:|...:...||.:|..
Zfish   422 WR-----SKLALDGDTVESITPDKVRGLRDLLNSSAMDIMYYTSPLYRDEITKGLTQELNRLYSL 481

  Fly  1667 YRMRHPEFNGG---VSLAGHSLGSLILFDLLCHQEPLKESEEENKENPDQLPQKQSS-------- 1720
            :..|:|:|.|.   ||:..||||.:|.||::...:|::...:|:.   |||..:.|.
Zfish   482 FCSRNPQFEGDGGKVSIISHSLGCVITFDIMTGWDPVRFCLQEHH---DQLEAEDSQWSSYEERH 543

  Fly  1721 --QKVQLPTSDPLPKQVSYAMGPEGTGQPVITYTQLIFHPKKFFALGSPIGMFVTIRGI--DKLG 1781
              ::||| |...|.:......|.: ..:|. ::..|.|..:.||.:|.|:.:|:.:|||  ...|
Zfish   544 LLEEVQL-TRQRLHELRDQLHGLK-ESKPA-SFPTLKFKVENFFCMGCPLAVFLALRGIRPGNTG 605

  Fly  1782 LDFHL---PTCPGFYNIFHPFDPVAYRIEALVNPDMNGIRPVLI---------PHHKGRKRMHLE 1834
            ...|:   ..|...:|||||.||||||:|.||....:.|.||.|         |:.:.|......
Zfish   606 HQDHIMPKSICRRLFNIFHPTDPVAYRLEPLVLKHYSKIAPVQIHWCNTINPTPYDEIRPTYLST 670

  Fly  1835 LKETMTRVGADIKQRFMDTFKTTLDSVNFLTTVTKVKKEA---EESLEK----------ETSQTS 1886
            .|:|    .:|::.....:....|...::..::|.:.|.:   ..||.|          ..|.:.
Zfish   671 SKDT----ASDMENGSSPSTSPVLARRHYGESITNLGKASILGAASLGKGIGGILFSHFSRSPSL 731

  Fly  1887 SQAFQKQTEDQDESSVA--------SSSCKLRNRTDSNSTTASDPEFIELDFPLGKLNDSKRVDY 1943
            ..|......|.::|...        |||..|.:.|            :|::         .|:|:
Zfish   732 PSAVDSGMGDSEDSQSTFTFSAIPPSSSSSLFDAT------------VEME---------HRIDF 775

  Fly  1944 VLQEAPLEFINEYIFALSSHVCYWGSEDTILFVMKEIYASLGISTDSQVPQSSM 1997
            .|:|..:|  :.|..|::||..||.|.|..||::..||...  ||:.....::|
Zfish   776 ELREGMVE--SRYWSAVTSHTAYWTSHDVALFLLTFIYKQQ--STEQTETSTAM 825

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
PAPLA1	NP_609185.1	WWE	1377..1446	CDD:280915	26/97 (27%)
		DDHD	1758..1981	CDD:280937	65/257 (25%)
ddhd1a	XP_005159001.1	DDHD	579..811	CDD:280937	65/258 (25%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2308
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1772
SonicParanoid	1	1.000	-	-		X662
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	5	4.840