Protein Alignment PAPLA1 and Ddhd1

DIOPT Version :9

• Sequence 1: NP_609185.1
• Gene: PAPLA1 / 34109
• FlyBaseID: FBgn0031990
• Length: 2016
• Species: Drosophila melanogaster
• Sequence 2: XP_006251831.1
• Gene: Ddhd1 / 305816
• RGDID: 1308576
• Length: 924
• Species: Rattus norvegicus
• Alignment Length: 970
• Identity: 217/970 - (22%)
• Similarity: 356/970 - (36%)
• Gaps: 288/970 - (29%)

  Fly  1210 GYFGGPSASAAQTFANETTNALVAPAINCDPVNFFDQVPQTQSQIQQANEDQRIQNFFNNPPLQD 1274
            |.|||...    .|.::..:.:....:..:|::           :....:|  :.:...:|.|.|
  Rat    30 GVFGGGGC----CFEHQPGDGVPLSLLRAEPLH-----------LAPGADD--LSHLALDPCLSD 77

  Fly  1275 QPAVPGELKYDI--VHSGVAVKQLQERSQTPVSNLVEPPSSACSEFSTLAPAPTQTDRQSGDDLL 1337
            :       .||.  ..||.:::...|            ..||....|:..|.|.......|...
  Rat    78 E-------NYDFSSAESGSSLRYYSE------------GESAGGGSSSSPPPPLVAPNSGGGGA- 122

  Fly  1338 QQHLGELPEDILRELRMASASSEKGQVATPPVAIPYSPVVAHWFYKRSVDTKFIWTPFSHYDS-- 1400
               .|..|.|..|......|:..:.:|.|     ...|....||||   :.|..|.||..|||
  Rat   123 ---AGGGPGDRKRSRPGGCAARHRYEVVT-----ELGPEEVRWFYK---EDKKTWKPFIGYDSLR 176

  Fly  1401 ------ALLET--------------------SLNLDDS--------------------TLIIP-- 1417
                  :||:|                    |...||.                    ..|.|
  Rat   177 IELAFRSLLQTTGSRARSADRDGDRVCGPTSSFREDDEDRACGFCPRAVGPEPEMEELVTIEPVC 241

  Fly  1418 VEGGRYDVNIKERTKTPVYW-EGKAIEVRRCSWFYKGVDSKYVPYTEDTAALLEAEYKRSAETGE 1481
            |.||.|:|::.:....|||| :...|.|.|..||   :|..:.|..|:.:.|:|.|: .|...|:
  Rat   242 VRGGLYEVDVTQGECYPVYWNQADKIPVMRGQWF---IDGTWQPLEEEESNLIEQEH-LSCFRGQ 302

  Fly  1482 WHQK---IMLA---NGE-------QVVFHGP--------------------------TVIVH-FL 1506
            ..|:   |.::   :|:       .||:|.|                          :..|| |.
  Rat   303 QMQENFDIEMSKSIDGKDGSGINYSVVYHIPPFSLPSLFKWRGYKESTDATGLKRKRSQAVHSFK 367

  Fly  1507 PQQNADTW-------------------------GASTQGSMRPRVVKRDLDDFTIEQGESQRVDH 1546
            ..:|...|                         |.|...|...|:.:..:::.|:|...|| ..|
  Rat   368 LSRNHVDWHSMDEVYLYSDATTSKIARTVTQKLGFSKASSSGTRLHRGYVEEATLEDKPSQ-TSH 431

  Fly  1547 LLFMVHGIGSACDLKMRSVEEVVDDFRVIAQQLVQSHYKNSTDMGLVGRVEVLPISWHGHLHSEE 1611
            ::|:|||||...| :.|.::... ..|..|:::.:.|:.|...     .||.||:.|...|..:.
  Rat   432 IVFVVHGIGQKMD-QGRIIKNTA-MMREAARKIEEKHFANHAT-----HVEFLPVEWRSKLTLDG 489

  Fly  1612 LGIDEKLKSITLESIPRLRNFTNDTLLDVLFYTSPKYCQKIMNTVADALNDVYLKYRMRHPEF-- 1674
            ..:|    |||.:.:..||:..|.:.:|:::||||.|..:::..:...||.:|..:..|:|:|
  Rat   490 DTVD----SITPDKVRGLRDMLNSSAMDIMYYTSPLYRDELVKGLQQELNRLYSLFCSRNPDFEE 550

  Fly  1675 -NGGVSLAGHSLGSLILFDLLCHQEPLKESE---EENKENPDQ--LPQKQSSQKVQLPTSDPLPK 1733
             .|.||:..||||.:|.:|::....|::..|   ::.:|.||:  :..::.....:|..:....:
  Rat   551 KGGKVSIVSHSLGCVITYDIMMGWNPVRLYEQLLQKEEELPDERWMSYEERHLLDELYITKRRLR 615

  Fly  1734 QVSYAM----GPEGTGQPVITYTQLIFHPKKFFALGSPIGMFVTIRGI--DKLGLDFH-LP--TC 1789
            ::...:    .|.|:..|.     |.|..:.||.:|||:.:|:.:|||  ...|...| ||  .|
  Rat   616 EIEDRLHGLKAPSGSQTPA-----LKFKVENFFCMGSPLAVFLALRGIRPGNTGSQDHILPREIC 675

  Fly  1790 PGFYNIFHPFDPVAYRIEALVNPDMNGIRPVLIPHHKGRKRMHLELKETMTRVGADIKQRFMDTF 1854
            ....|||||.||||||:|.|:....:.|.||.|..:.....:..|          .:|..|::..
  Rat   676 NRLLNIFHPTDPVAYRLEPLILKHYSNISPVQIHWYNTSNPLPYE----------HMKPNFLNPA 730

  Fly  1855 K---TTLDSVNF--------------------LTTVTKV-------------------------- 1870
            |   :..:|.|.                    :|.:.|.
  Rat   731 KEPTSASESENIAAIPSPVTSPVLSRRHYGESITNIGKASILGAASIGKGLGGMLFSRFGRSSTP 795

  Fly  1871 -----KKEAEESLEKETSQTSSQAFQKQTEDQDESSVASSS-CKLRNR--------TDSNSTTAS 1921
                 .|::.|..:|..|..|:.....||.....|....|: .:|:..        ...|...:.
  Rat   796 QPSEPSKDSAEEEKKPVSSPSTTTVATQTLPHSSSGFLDSAYFRLQESFFYLPQLLFPENVMQSK 860

  Fly  1922 DPEFIELDFPLGKLNDSKRVDYVLQEAPLEFINEYIFALSSHVCYWGSEDTILFVMKEIY 1981
            |...:||:         .|:|:.|:|..:|  :.|..|::||..||.|.|..||::..:|
  Rat   861 DDSLVELE---------HRIDFELREGLVE--SRYWSAVTSHTAYWSSLDVALFLLTFMY 909

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
PAPLA1	NP_609185.1	WWE	1377..1446	CDD:280915	30/119 (25%)
		DDHD	1758..1981	CDD:280937	68/290 (23%)
Ddhd1	XP_006251831.1	DDHD	638..909	CDD:280937	68/291 (23%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2308
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X662
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.810