Protein Alignment PAPLA1 and SPCC1020.13c

DIOPT Version :9

• Sequence 1: NP_609185.1
• Gene: PAPLA1 / 34109
• FlyBaseID: FBgn0031990
• Length: 2016
• Species: Drosophila melanogaster
• Sequence 2: NP_587946.1
• Gene: SPCC1020.13c / 2539084
• PomBaseID: SPCC1020.13c
• Length: 669
• Species: Schizosaccharomyces pombe
• Alignment Length: 757
• Identity: 163/757 - (21%)
• Similarity: 258/757 - (34%)
• Gaps: 271/757 - (35%)

  Fly  1380 WFYKRSVD----TKFI-------WTPFSHYDSALLETSLN----------LDDSTLIIPVEGGRY 1423
            |||..:.|    |..:       |..|.:||:..||...|          .:...:|:.: .|.:
pombe    15 WFYLSNYDLYDETSSMELTGAQSWRRFLNYDNNALEAKYNEIITEEVSQEPNQKNVIVGI-SGLH 78

  Fly  1424 DVNIKERTKTPVYW----EGKAIEVRRCSWFYKGVDSKYVPYTEDTAALLEAEYKRSAETGEWHQ 1484
            .||:...|..|:||    :...:.|.|..|.|           |||...:..|.....|.|....
pombe    79 VVNLPTLTLKPLYWPSASKNDTLRVVRGLWMY-----------EDTGLPVINELSDMLEEGYQEV 132

  Fly  1485 KIMLANGEQVVFH---------GPTVIVHFLPQQNADTWGA------------------------ 1516
            |....|.:.|:..         .|:|:.|...:.:.:...|
pombe   133 KPYAVNWDNVLKEEEEGKDSQDDPSVLSHKRNKSSKELIDAMQWPLKPTSSGKYVFYEDGYRALI 197

  Fly  1517 --------------STQGSMRPRVVKRDLDDFTIE--QGESQRVDHLLFMVHGIGSACDLKMRSV 1565
                          |.:.|::...|.||...|..:  .|..|..| |..:|||||.    |....
pombe   198 CQGGLLSYFSKGTQSRRTSIKGMPVVRDFPYFEDDGFNGPKQVTD-LFLVVHGIGQ----KRSET 257

  Fly  1566 EE------VVDDFRVIAQ---------QLVQSHYKNSTDMGLVGRVEVLPISW------------ 1603
            ||      ..:.||.:.|         .|:::.|:          .::|||.|
pombe   258 EERFLFTKTCNVFRSLIQIQKNIMKEDPLIRNDYE----------PQLLPICWRNKLNFNSYIKP 312

  Fly  1604 ----HGHLHSEELGIDE-KLKSITLESIPRLRNFTNDTLLDVLFYTSPKYCQKIMNTVADALNDV 1663
                .|.:..||...:. .::.|.::|||.:|....|.:.|:.:|.| .:.:.|:.:|....|.|
pombe   313 VAGDEGRVEDEEFEENRFSIEDIEIDSIPAVRRLLGDVMSDIPYYMS-HHKESIIKSVIREANRV 376

  Fly  1664 YLKYRMRHPEF---NGGVSLAGHSLGSLILFDLLCHQEP-LKESEEENKENPDQLPQKQSSQKVQ 1724
            |..::..:|.|   .|.:.:.||||||.::||:|..|.. :||...::.|
pombe   377 YHLWKDCNPYFLENKGRIFIIGHSLGSTVVFDILSLQPTFVKEITIDDDE--------------- 426

  Fly  1725 LPTSDPLPKQVSYAMGPEGTGQPVITYTQLIFHPKKFFALGSPIGMFVTI----------RG--- 1776
                                       :..||....||..|.|:|.|:.:          ||
pombe   427 ---------------------------SCFIFDTNGFFCFGGPVGFFLHLNQQSIIPRRGRGSSR 464

  Fly  1777 --IDKLGLDFHLP---TCPG-----------FYNIFHPFDPVAYRIEALVNPDMN-GIRPVLIPH 1824
              |:|..::..:|   |..|           ||||::..||||.|:...|:...: ||.|..|
pombe   465 YEINKNFINSDVPKSYTYDGYDRYGCLAVDSFYNIYNHLDPVAMRLNPTVDLSFSKGIHPTRI-- 527

  Fly  1825 HKGRKRMHLELKETMTRVGADIKQRF--MDTFKTTLDSVNFLTTVTK-------VKKEAEESLEK 1880
                         ..||..:.|.:..  .:|....|.|.|......|       |..|.|:::|.
pombe   528 -------------LFTRKSSSILRMISHSNTDPVELRSYNQSLQQNKNNEPTAVVPLEPEQTVEL 579

  Fly  1881 ETSQTSSQAFQKQTEDQDESSVASSSCKLRNRTDSNSTTASDPEFIELDFPLGKLNDSKRVDYVL 1945
            ||     :.|:::           ...|.|                     :.:||::.::|||.
pombe   580 ET-----RNFRRE-----------ERAKWR---------------------MQELNENSQLDYVF 607

  Fly  1946 QEAPLEFINEYIFALSSHVCYWGSEDTILFVMKEIYASLGIS 1987
            ..|.....|:|:..||:|..||.|||...|::.|...:.||:
pombe   608 TSAHGVISNKYLSMLSAHSSYWSSEDLACFLVVETGRNFGIA 649

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
PAPLA1	NP_609185.1	WWE	1377..1446	CDD:280915	21/90 (23%)
		DDHD	1758..1981	CDD:280937	62/261 (24%)
SPCC1020.13c	NP_587946.1	DDHD	436..638	CDD:280937	60/253 (24%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2308
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR23509
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1772
SonicParanoid	1	1.000	-	-		X662
TreeFam	1	0.960	-	-
	6	5.900