DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG12375 and AT1G25375

DIOPT Version :9

Sequence 1:	NP_609183.1	Gene:	CG12375 / 34106	FlyBaseID:	FBgn0031987	Length:	292	Species:	Drosophila melanogaster
Sequence 2:	NP_564232.1	Gene:	AT1G25375 / 839123	AraportID:	AT1G25375	Length:	524	Species:	Arabidopsis thaliana

Alignment Length:	261	Identity:	67/261 - (25%)
Similarity:	110/261 - (42%)	Gaps:	56/261 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly    47 GDEDVPQYIAHLGDVL-----------QQEKASIDT------ILLTHWHHDHVGGVKSIVGTKLA 94
            ||.....::|| ||.|           .:.|..:|.      :.:||.|.||:.|:.:|   :.:
plant   222 GDHQGADFVAH-GDALIVDPGCLSKLHVELKKIVDALPRKLIVFVTHHHRDHIDGLSAI---QES 282

  Fly    95 EKDCRVFKFGRTDAPDVCPEIPTDIKLH----------PLAHNQEFTTEGANVRVVHTPGHTTDH 149
            ..|..:....:|              .|          |::..:.....|..:.|:..||||..|
plant   283 NPDAILVAHAKT--------------RHRIGGWSGNYTPVSGGENIYVNGQKLTVIFAPGHTDGH 333

  Fly   150 V-VLAMNEGTLFSGDCILGEGTAVFE-----DLFEYMKSLEKILDIKPQRIFPGHGNVIEEPIGK 208
            : :|..:..:|..||..:|:|:|..:     ::.:|.:|..|.|::.|..:.|.||.|...|...
plant   334 MSLLHTSTQSLIVGDHCVGQGSAFLDIRAGGNMTDYFQSTYKFLELSPNVVIPMHGRVNLWPKHM 398

  Fly   209 IEYYINHRNQREQQILQFFVQRPNENLQAM-DVVKVVYKETPENLWPAAAYNVNHHLSKLEKEGK 272
            :..|:.:|..||:.||:..|    :..|.: |:|..||.......|.||:.||..|:.||..|.|
plant   399 LCGYLKNRRSREKSILKATV----DGAQTLYDIVAKVYSSVDRKFWWAASSNVRLHIEKLAVENK 459

  Fly   273 L 273
            |
plant   460 L 460

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG12375	NP_609183.1	LACTB2-like_MBL-fold	13..202	CDD:293808	42/187 (22%)
CG12375	NP_609183.1	GloB	25..240	CDD:223565	52/226 (23%)
AT1G25375	NP_564232.1	metallo-hydrolase-like_MBL-fold	231..385	CDD:419960	37/171 (22%)
AT1G25375	NP_564232.1	BLACT_WH	423..>459	CDD:407650	13/35 (37%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	43	1.000	Domainoid score	I4750
eggNOG	1	0.900	-	-		E1_COG0491
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D576967at2759
OrthoFinder	1	1.000	-	-		FOG0005792
OrthoInspector	1	1.000	-	-		oto2992
orthoMCL	1	0.900	-	-		OOG6_101772
Panther	1	1.100	-	-	LDO	PTHR23131
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X4183
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	10	9.780