Protein Alignment CG12375 and LACTB2

DIOPT Version :9

• Sequence 1: NP_609183.1
• Gene: CG12375 / 34106
• FlyBaseID: FBgn0031987
• Length: 292
• Species: Drosophila melanogaster
• Sequence 2: NP_057111.1
• Gene: LACTB2 / 51110
• HGNCID: 18512
• Length: 288
• Species: Homo sapiens
• Alignment Length: 305
• Identity: 135/305 - (44%)
• Similarity: 181/305 - (59%)
• Gaps: 46/305 - (15%)

  Fly     2 ALIPAVTRLTSSVIRILGCNPSAMTLQGTNTYLLGSGSRRILIDTGDEDVPQYIAHLGDVLQQEK 66
            |::..|.||::.|:|:|||||..||||||||||:|:|.||||||||:..:|:||:.|...|.:..
Human     3 AVLQRVERLSNRVVRVLGCNPGPMTLQGTNTYLVGTGPRRILIDTGEPAIPEYISCLKQALTEFN 67

  Fly    67 ASIDTILLTHWHHDHVGGVKSIVGTKLAEKDCRVFKFGRTDAPDVCPEIPTD----IKLHP---- 123
            .:|..|::||||.||.||:                       .|:|..|..|    ||..|
Human    68 TAIQEIVVTHWHRDHSGGI-----------------------GDICKSINNDTTYCIKKLPRNPQ 109

  Fly   124 --------------LAHNQEFTTEGANVRVVHTPGHTTDHVVLAM-NEGTLFSGDCILGEGTAVF 173
                          |.......||||.:||::|||||.||:.|.: .|..:|||||||||||.||
Human   110 REEIIGNGEQQYVYLKDGDVIKTEGATLRVLYTPGHTDDHMALLLEEENAIFSGDCILGEGTTVF 174

  Fly   174 EDLFEYMKSLEKILDIKPQRIFPGHGNVIEEPIGKIEYYINHRNQREQQILQFFVQRPNENLQAM 238
            |||::||.||:::|.||...|:||||.||.....||:.||:|||.||||||..|.:...::...|
Human   175 EDLYDYMNSLKELLKIKADIIYPGHGPVIHNAEAKIQQYISHRNIREQQILTLFRENFEKSFTVM 239

  Fly   239 DVVKVVYKETPENLWPAAAYNVNHHLSKLEKEGKLRVSKSADEEF 283
            ::||::||.|||||...|.:|:..||.|||||||:..:...|:::
Human   240 ELVKIIYKNTPENLHEMAKHNLLLHLKKLEKEGKIFSNTDPDKKW 284

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG12375	NP_609183.1	LACTB2-like_MBL-fold	13..202	CDD:293808	93/211 (44%)
		GloB	25..240	CDD:223565	103/237 (43%)
LACTB2	NP_057111.1	LACTB2-like_MBL-fold	14..203	CDD:293808	93/211 (44%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165159974
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0491
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H9349
Inparanoid	1	1.050	254	1.000	Inparanoid score	I3199
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG61746
OrthoDB	1	1.010	-	-		D432155at33208
OrthoFinder	1	1.000	-	-		FOG0005792
OrthoInspector	1	1.000	-	-		oto90749
orthoMCL	1	0.900	-	-		OOG6_101772
Panther	1	1.100	-	-	LDO	PTHR23131
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2602
SonicParanoid	1	1.000	-	-		X4183
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	14	13.840