Protein Alignment CG12375 and HAGH

DIOPT Version :9

• Sequence 1: NP_609183.1
• Gene: CG12375 / 34106
• FlyBaseID: FBgn0031987
• Length: 292
• Species: Drosophila melanogaster
• Sequence 2: NP_005317.2
• Gene: HAGH / 3029
• HGNCID: 4805
• Length: 308
• Species: Homo sapiens
• Alignment Length: 283
• Identity: 62/283 - (21%)
• Similarity: 103/283 - (36%)
• Gaps: 93/283 - (32%)

  Fly    30 TNTYLLGSGSRRILIDTGDEDV-------PQYIAHLGDVLQQEKASIDTILLTHWHHDHVGGVKS 87
            |:.|:.      ::||...::.       ||.:.   |..::....:.|:|.||.|.||.||.:.
Human    58 TDNYMY------LVIDDETKEAAIVDPVQPQKVV---DAARKHGVKLTTVLTTHHHWDHAGGNEK 113

  Fly    88 IV----GTKLAEKDCRVFKFGRTDAPDVCPEIPTDIKLHPLAHNQEFTTEGANVRVVHTPGHTTD 148
            :|    |.|:...|.|:                 ....|.:.|.........||:.:.||.||:.
Human   114 LVKLESGLKVYGGDDRI-----------------GALTHKITHLSTLQVGSLNVKCLATPCHTSG 161

  Fly   149 HVVLAMNE------GTLFSGDCILGEGTAVFED--LFEYMKSLEKILDIKP--QRIFPGHGNVIE 203
            |:...:::      ..:|:||.:...|...|.:  ..|..|:|.::|...|  .|::.||
Human   162 HICYFVSKPGGSEPPAVFTGDTLFVAGCGKFYEGTADEMCKALLEVLGRLPPDTRVYCGH----- 221

  Fly   204 EPIGKIEYYINHRNQREQQILQF--FVQRPNENLQAMDVVKVVYKETPENL-WPAAAYNVNHHLS 265
                  ||.||:        |:|  .|:..|..::             |.| |....|::
Human   222 ------EYTINN--------LKFARHVEPGNAAIR-------------EKLAWAKEKYSI----- 254

  Fly   266 KLEKEGKLRVSKSADEEFYVYQP 288
                 |:..|..:..||| .|.|
Human   255 -----GEPTVPSTLAEEF-TYNP 271

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG12375	NP_609183.1	LACTB2-like_MBL-fold	13..202	CDD:293808	43/192 (22%)
		GloB	25..240	CDD:223565	51/232 (22%)
HAGH	NP_005317.2	PLN02469	49..304	CDD:178088	62/283 (22%)
		hydroxyacylglutathione_hydrolase_MBL-fold	52..221	CDD:293809	41/188 (22%)
		HAGH_C	222..302	CDD:292741	19/82 (23%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0491
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810