DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG12375 and AgaP_AGAP004236

DIOPT Version :9

Sequence 1:	NP_609183.1	Gene:	CG12375 / 34106	FlyBaseID:	FBgn0031987	Length:	292	Species:	Drosophila melanogaster
Sequence 2:	XP_313152.3	Gene:	AgaP_AGAP004236 / 1274081	VectorBaseID:	AGAP004236	Length:	291	Species:	Anopheles gambiae

Alignment Length:	297	Identity:	173/297 - (58%)
Similarity:	211/297 - (71%)	Gaps:	11/297 - (3%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MALIPAVTRLTSSVIRILGCNPSAMTLQGTNTYLLGSGSRRILIDTGDEDVPQYIAHLGDVLQQE 65
            ||.||||:|::|.:|||||||||.||||||||||:|||.||||:||||.:|.:||.||..||..|
Mosquito     1 MATIPAVSRISSRLIRILGCNPSPMTLQGTNTYLIGSGKRRILLDTGDANVKEYIGHLQKVLMDE 65

  Fly    66 KASIDTILLTHWHHDHVGGVKSIVGTKLAEKD-CRVFKFGRTDAPDVCPEIPTDIKLHPLAHNQE 129
            :..|:.|:::||||||||||..|:.. :..|| |.|:||.|||||:  ||: ....|..|...|.
Mosquito    66 RVLINDIIISHWHHDHVGGVDDILEV-IDNKDTCNVWKFPRTDAPE--PEV-KHATLKELKDGQI 126

  Fly   130 FTTEGANVRVVHTPGHTTDHVVLAMNE-GTLFSGDCILGEGTAVFEDLFEYMKSLEKILDIKPQR 193
            ||||||.::|:||||||||||||.:.| .:|||.||||||||.|||||:.||||||.||:..|..
Mosquito   127 FTTEGATLKVIHTPGHTTDHVVLVLQEDNSLFSADCILGEGTTVFEDLYLYMKSLETILNANPTV 191

  Fly   194 IFPGHGNVIEEPIGKIEYYINHRNQREQQILQFFVQRPNENLQAMDVVKVVYKETPENLWPAAAY 258
            |:|||||:|.:|..::..||||||.||:||...|...|::....||:|:.|||||||.||.||||
Mosquito   192 IYPGHGNIINDPAERVTEYINHRNHREKQIFAVFEANPDKQYNEMDIVRTVYKETPEQLWAAAAY 256

  Fly   259 NVNHHLSKLEKEGKLRVSKSADEE---FYVYQPTSAL 292
            ||||||.||..||||  .:..|.|   .:.|.|..:|
Mosquito   257 NVNHHLKKLTVEGKL--LECVDSEGGNSWKYVPAPSL 291

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG12375	NP_609183.1	LACTB2-like_MBL-fold	13..202	CDD:293808	118/190 (62%)
CG12375	NP_609183.1	GloB	25..240	CDD:223565	124/216 (57%)
AgaP_AGAP004236	XP_313152.3	GloB	9..229	CDD:223565	133/223 (60%)
AgaP_AGAP004236	XP_313152.3	LACTB2-like_MBL-fold	13..200	CDD:293808	118/190 (62%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	121	1.000	Domainoid score	I11268
eggNOG	1	0.900	-	-		E1_COG0491
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H9349
Inparanoid	1	1.050	336	1.000	Inparanoid score	I4673
OMA	1	1.010	-	-		QHG61746
OrthoDB	1	1.010	-	-		D432155at33208
OrthoFinder	1	1.000	-	-		FOG0005792
OrthoInspector	1	1.000	-	-		oto109777
Panther	1	1.100	-	-	LDO	PTHR23131
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X4183
TreeFam	1	0.960	-	-
	13	12.940