DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG8673 and si:dkey-175m17.6

DIOPT Version :9

Sequence 1:	NP_609182.1	Gene:	CG8673 / 34105	FlyBaseID:	FBgn0031986	Length:	420	Species:	Drosophila melanogaster
Sequence 2:	XP_005161436.1	Gene:	si:dkey-175m17.6 / 100007286	ZFINID:	ZDB-GENE-091204-392	Length:	441	Species:	Danio rerio

Alignment Length:	463	Identity:	100/463 - (21%)
Similarity:	181/463 - (39%)	Gaps:	101/463 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly     5 LLRCILI---LILVSFTVFTYVSKVGVMEKVD-YF----TTAKPDVMSKNPA-----IQLVGEAI 56
            ||.|:::   |:.:..:||..||....:.::. :|    .:|....::.:|.     ::|...|:
Zfish    15 LLPCVMVSHLLVYIMVSVFVAVSYSPPVPQLPLHFIATGASANSGALASHPVRPFWNLRLEDGAL 79

  Fly    57 --RLRSF--RE--PIKDFDDGFAVQISGNSSEGNKDIYTTIDGNINVADSIAAIRSRRIDEEKLH 115
              ||:..  ||  ||          :.||::.....   ::|.:    ..:..|:|...:::|..
Zfish    80 WNRLQHIWDREHNPI----------LRGNTTRSTSQ---SLDSD----QPLEMIKSHACEQDKAW 127

  Fly   116 DDGLDSKDILAK--KSVVLYSIDTEVPVRMPLVKTIYKPGHLDSEIDMERICPQKGLSTQ-LLVL 177
            ...|...:.|..  |..||     .:..|           |....:|...:|..:...|. ||:.
Zfish   128 ASHLPDFNTLPNQMKDFVL-----SMHCR-----------HYAILVDQPDLCAGQDSETPFLLMA 176

  Fly   178 ITSSLRHSAARMSIRQTWMHYGSRRDVG--------MAFVLGK-----GKNKSVKKAIDQEDFMY 229
            |.|.:.:...|.:||:||...|..::.|        ..|:|.:     |.:..:...:..|...:
Zfish   177 IKSQIGNFENRQAIRETWGKSGPIQEGGGGRGWLVRTVFLLARQDTETGPHPDLNALLKLESSTH 241

  Fly   230 QDLIRGHFIDSYNNLTLKTISLLEWADLHCPKAKYVLKTDDDMFINVPKLLTLISTLKANRT--- 291
            :|::...|.||:.|||||.:....|...|||:..::.|.|||:|:....||..:..::..:|
Zfish   242 KDILLWDFKDSFFNLTLKDVLFWNWLSKHCPQVHFIFKGDDDVFVRTKALLDYLDQIRVEKTRGN 306

  Fly   292 --------IYGRRAENWKPIRNRWSKYHISNAQYGKPTFPYFTTGPAYLLTGDIVHALYVQSLNT 348
                    :.|....|..|.|...:||:|..:.| |.|:|.:..|...:.:|.:...|...|...
Zfish   307 KTKGLVDFVVGDVIANAWPNRQPNTKYYIPESFY-KGTYPTYPGGGGVVYSGALAMRLQEVSRWV 370

  Fly   349 AFLKLEDVFTTGIVAESLNIRRV------------NVREMANTRTKFETCHIRDKITIHMVRNNE 401
            :...::||| .|:....|.:...            :||:        :.|...:.:.:|.....|
Zfish   371 SLFPIDDVF-LGMCLHRLGVPPTHHSGFLTFDLPEDVRD--------KPCAYHNVLLVHRRTPKE 426

  Fly   402 QFTLWNML 409
            ..|||..|
Zfish   427 MLTLWKEL 434

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG8673	NP_609182.1	Galactosyl_T	186..374	CDD:304462	52/223 (23%)
si:dkey-175m17.6	XP_005161436.1	Galactosyl_T	187..393	CDD:304462	52/207 (25%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2287
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1037602at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X41
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	4	3.820