DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Trf and SPT15

DIOPT Version :9

Sequence 1:	NP_476939.1	Gene:	Trf / 34102	FlyBaseID:	FBgn0010287	Length:	224	Species:	Drosophila melanogaster
Sequence 2:	NP_011075.3	Gene:	SPT15 / 856891	SGDID:	S000000950	Length:	240	Species:	Saccharomyces cerevisiae

Alignment Length:	239	Identity:	113/239 - (47%)
Similarity:	153/239 - (64%)	Gaps:	22/239 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly     7 VADAER-----DRDNVAATSNA----------AANPHAALQPQQPVALVEPKDAQHEI------- 49
            :||.||     :.:.:....|.          ...|....|.::.:....|:..:...
Yeast     1 MADEERLKEFKEANKIVFDPNTRQVWENQNRDGTKPATTFQSEEDIKRAAPESEKDTSATSGIVP 65

  Fly    50 RLQNIVATFSVNCELDLKAINSRTRNSEYSPKRFRGVIMRMHSPRCTALIFRTGKVICTGARNEI 114
            .|||||||.::.|.||||.:....||:||:||||..||||:..|:.|||||.:||::.|||::|.
Yeast    66 TLQNIVATVTLGCRLDLKTVALHARNAEYNPKRFAAVIMRIREPKTTALIFASGKMVVTGAKSED 130

  Fly   115 EADIGSRKFARILQKLGFPVKFMEYKLQNIVATVDLRFPIRLENLNHVHGQFSSYEPEMFPGLIY 179
            ::.:.|||:|||:||:||..||.::|:||||.:.|::||||||.|...||.|||||||:||||||
Yeast   131 DSKLASRKYARIIQKIGFAAKFTDFKIQNIVGSCDVKFPIRLEGLAFSHGTFSSYEPELFPGLIY 195

  Fly   180 RMVKPRIVLLIFVNGKVVFTGAKSRKDIMDCLEAISPILLSFRK 223
            |||||:|||||||:||:|.||||.|::|....|||.|:|..|||
Yeast   196 RMVKPKIVLLIFVSGKIVLTGAKQREEIYQAFEAIYPVLSEFRK 239

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Trf	NP_476939.1	PLN00062	49..224	CDD:177693	105/182 (58%)
Trf	NP_476939.1	TBP_eukaryotes	50..221	CDD:239952	102/170 (60%)
SPT15	NP_011075.3	PLN00062	64..239	CDD:177693	103/174 (59%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG2101
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG62182
OrthoFinder	1	1.000	-	-		FOG0001202
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100597
Panther	1	1.100	-	-	O	PTHR10126
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	7	6.780