DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Trf and Tbpl2

DIOPT Version :9

Sequence 1:	NP_476939.1	Gene:	Trf / 34102	FlyBaseID:	FBgn0010287	Length:	224	Species:	Drosophila melanogaster
Sequence 2:	NP_001092831.1	Gene:	Tbpl2 / 680050	RGDID:	1596837	Length:	344	Species:	Rattus norvegicus

Alignment Length:	227	Identity:	110/227 - (48%)
Similarity:	159/227 - (70%)	Gaps:	11/227 - (4%)

- Green bases have known domain annotations that are detailed below.

  Fly     8 ADAERDRDNVAATSNAAANPHAALQPQQ---PVALVEPKDAQHEI--------RLQNIVATFSVN 61
            :::..|..:...:.:|.:|..::..|..   ||.|:......:.:        :|||:|:|.::.
  Rat   117 SNSSPDTQSCLCSHDADSNQLSSETPNSNALPVVLISSMTPMNPVTECSGIVPQLQNVVSTANLA 181

  Fly    62 CELDLKAINSRTRNSEYSPKRFRGVIMRMHSPRCTALIFRTGKVICTGARNEIEADIGSRKFARI 126
            |:|||:.|....:|:||:||||..||||:..||.|||||.:|||:||||::|.|:.:.:||:||:
  Rat   182 CKLDLRKIALNAKNTEYNPKRFAAVIMRIREPRTTALIFSSGKVVCTGAKSEDESRLAARKYARV 246

  Fly   127 LQKLGFPVKFMEYKLQNIVATVDLRFPIRLENLNHVHGQFSSYEPEMFPGLIYRMVKPRIVLLIF 191
            :|||||||:|..:|:||:||:.|::||||||.|...|.||||||||:||||||:||||::|||||
  Rat   247 VQKLGFPVRFFNFKIQNMVASCDVKFPIRLEILALTHRQFSSYEPELFPGLIYKMVKPQVVLLIF 311

  Fly   192 VNGKVVFTGAKSRKDIMDCLEAISPILLSFRK 223
            .:||||.||||.|.:|.:..|.:.|||.||:|
  Rat   312 ASGKVVLTGAKERSEIYEAFENMYPILESFKK 343

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Trf	NP_476939.1	PLN00062	49..224	CDD:177693	103/183 (56%)
Trf	NP_476939.1	TBP_eukaryotes	50..221	CDD:239952	100/170 (59%)
Tbpl2	NP_001092831.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	78..143		3/25 (12%)
		PLN00062	168..344	CDD:177693	103/176 (59%)
		TBP_eukaryotes	168..341	CDD:239952	100/172 (58%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG2101
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1219067at2759
OrthoFinder	1	1.000	-	-		FOG0001202
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100597
Panther	1	1.100	-	-	O	PTHR10126
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	7	6.820