DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Trf and TBPL2

DIOPT Version :9

Sequence 1:	NP_476939.1	Gene:	Trf / 34102	FlyBaseID:	FBgn0010287	Length:	224	Species:	Drosophila melanogaster
Sequence 2:	NP_950248.2	Gene:	TBPL2 / 387332	HGNCID:	19841	Length:	343	Species:	Homo sapiens

Alignment Length:	227	Identity:	115/227 - (50%)
Similarity:	157/227 - (69%)	Gaps:	24/227 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly    21 SNAAANPHAAL----------QPQQP------VALVEPKDAQHEI--------RLQNIVATFSVN 61
            |::.:|.|:.|          .|::|      :|.:.|......|        :|||||:|.::.
Human   116 SSSLSNSHSQLHPGDTDSVQPSPEKPNSDSLSLASITPMTPMTPISECCGIVPQLQNIVSTVNLA 180

  Fly    62 CELDLKAINSRTRNSEYSPKRFRGVIMRMHSPRCTALIFRTGKVICTGARNEIEADIGSRKFARI 126
            |:||||.|....:|:||:||||..||||:..||.|||||.:||::||||::|.::.:.:||:||:
Human   181 CKLDLKKIALHAKNAEYNPKRFAAVIMRIREPRTTALIFSSGKMVCTGAKSEEQSRLAARKYARV 245

  Fly   127 LQKLGFPVKFMEYKLQNIVATVDLRFPIRLENLNHVHGQFSSYEPEMFPGLIYRMVKPRIVLLIF 191
            :||||||.:|:::|:||:|.:.|:|||||||.|...|.||||||||:||||||||||||||||||
Human   246 VQKLGFPARFLDFKIQNMVGSCDVRFPIRLEGLVLTHQQFSSYEPELFPGLIYRMVKPRIVLLIF 310

  Fly   192 VNGKVVFTGAKSRKDIMDCLEAISPILLSFRK 223
            |:||||.||||.|.:|.:..|.|.|||..|:|
Human   311 VSGKVVLTGAKERSEIYEAFENIYPILKGFKK 342

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Trf	NP_476939.1	PLN00062	49..224	CDD:177693	107/183 (58%)
Trf	NP_476939.1	TBP_eukaryotes	50..221	CDD:239952	104/170 (61%)
TBPL2	NP_950248.2	None

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG2101
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1219067at2759
OrthoFinder	1	1.000	-	-		FOG0001202
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100597
Panther	1	1.100	-	-	O	PTHR10126
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	6	5.820