DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Trf and Trf2

DIOPT Version :9

Sequence 1:	NP_476939.1	Gene:	Trf / 34102	FlyBaseID:	FBgn0010287	Length:	224	Species:	Drosophila melanogaster
Sequence 2:	NP_001096905.1	Gene:	Trf2 / 31773	FlyBaseID:	FBgn0261793	Length:	1715	Species:	Drosophila melanogaster

Alignment Length:	228	Identity:	77/228 - (33%)
Similarity:	128/228 - (56%)	Gaps:	13/228 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MQFHFKVADAERDRDNVAATSNAAANPHAALQPQQPVALVEPKDAQHE--IRLQNIVATFSVNCE 63
            ||....:.|.:.::..||.....::|....:...||:|     |.:||  |.:.|:|.:|||.|.
  Fly  1240 MQSITVIDDDDEEKKEVAEDEEESSNNAKPIDLHQPIA-----DNEHELDIVINNVVCSFSVGCH 1299

  Fly    64 LDLKAINSRTRNSEYSPKRFRGVI-MRMHSPRCTALIFRTGKVICTGARNEIEADIGSRKFARIL 127
            |.|:.|..:..|.||  :|..|:: |::..|..||.|:.:|::.||||.:|..|.:.:|::||.|
  Fly  1300 LKLREIALQGSNVEY--RRENGMVTMKLRHPYTTASIWSSGRITCTGATSESMAKVAARRYARCL 1362

  Fly   128 QKLGFPVKFMEYKLQNIVATVDLRFPIRLENLNHVHGQFSSYEPEMFPGLIYRM--VKPRIVLLI 190
            .|||||.:|:.:::.|::.|..:.:.|::.|.:..|.:.:|||||:.||:.|:|  ..|:..|.|
  Fly  1363 GKLGFPTRFLNFRIVNVLGTCSMPWAIKIVNFSERHRENASYEPELHPGVTYKMRDPDPKATLKI 1427

  Fly   191 FVNGKVVFTGAKSRKDIMDCLEAISPILLSFRK 223
            |..|.|..|.| |...:...::.|.|::..|||
  Fly  1428 FSTGSVTVTAA-SVNHVESAIQHIYPLVFDFRK 1459

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Trf	NP_476939.1	PLN00062	49..224	CDD:177693	65/178 (37%)
Trf	NP_476939.1	TBP_eukaryotes	50..221	CDD:239952	61/173 (35%)
Trf2	NP_001096905.1	GBP_C	<967..1068	CDD:303769
		coiled coil	1037..1048	CDD:293879
		coiled coil	1057..1068	CDD:293879
		TLF	1283..1456	CDD:239953	62/175 (35%)
		PLN00062	1285..1459	CDD:177693	63/176 (36%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG2101
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1219067at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR10126
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	4	3.920