DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Trf and tbp-1

DIOPT Version :9

Sequence 1:	NP_476939.1	Gene:	Trf / 34102	FlyBaseID:	FBgn0010287	Length:	224	Species:	Drosophila melanogaster
Sequence 2:	NP_001370645.1	Gene:	tbp-1 / 176054	WormBaseID:	WBGene00006542	Length:	340	Species:	Caenorhabditis elegans

Alignment Length:	213	Identity:	116/213 - (54%)
Similarity:	153/213 - (71%)	Gaps:	9/213 - (4%)

- Green bases have known domain annotations that are detailed below.

  Fly    13 DRDNVAATSNA-AANPHAALQPQQPVALVE-PKDAQHEIRLQNIVATFSVNCELDLKAINSRTRN 75
            |||  |.|..| |:|..|.:.|..|.:.:: |..|     |||||:|.::..:||||.|....||
Worm   135 DRD--ALTHQAPASNIAATMVPATPASQLDIPMPA-----LQNIVSTVNLGVQLDLKKIALHARN 192

  Fly    76 SEYSPKRFRGVIMRMHSPRCTALIFRTGKVICTGARNEIEADIGSRKFARILQKLGFPVKFMEYK 140
            :||:||||..||||:..||.|||||.:||::||||::|..:.:.:||:|||:|||||..||.|:.
Worm   193 AEYNPKRFAAVIMRIREPRTTALIFSSGKMVCTGAKSEEASRLAARKYARIVQKLGFQAKFTEFM 257

  Fly   141 LQNIVATVDLRFPIRLENLNHVHGQFSSYEPEMFPGLIYRMVKPRIVLLIFVNGKVVFTGAKSRK 205
            :||:|.:.|:||||:||.|...|.|||:||||:||||||||||||:||||||:||||.||||:::
Worm   258 VQNMVGSCDVRFPIQLEGLCITHSQFSTYEPELFPGLIYRMVKPRVVLLIFVSGKVVITGAKTKR 322

  Fly   206 DIMDCLEAISPILLSFRK 223
            ||.:....|.|||..|:|
Worm   323 DIDEAFGQIYPILKGFKK 340

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Trf	NP_476939.1	PLN00062	49..224	CDD:177693	103/175 (59%)
Trf	NP_476939.1	TBP_eukaryotes	50..221	CDD:239952	101/170 (59%)
tbp-1	NP_001370645.1	TBP_eukaryotes	165..338	CDD:239952	102/177 (58%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG2101
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1219067at2759
OrthoFinder	1	1.000	-	-		FOG0001202
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100597
Panther	1	1.100	-	-	O	PTHR10126
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	7	6.820