DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CCDC53 and washc3

DIOPT Version :9

Sequence 1:	NP_609178.1	Gene:	CCDC53 / 34097	FlyBaseID:	FBgn0031979	Length:	176	Species:	Drosophila melanogaster
Sequence 2:	NP_956467.1	Gene:	washc3 / 393142	ZFINID:	ZDB-GENE-040426-783	Length:	200	Species:	Danio rerio

Alignment Length:	183	Identity:	76/183 - (41%)
Similarity:	102/183 - (55%)	Gaps:	12/183 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly     2 DATAAITGNVDKTQIPPLNQKRILAFVNHFLVSTCTFLNEFALGCETKFVEMERQLQKTEAALII 66
            |....:...||.|::|.:.|:||:||:|.|:|.|..|||.|:..||.|...:..::|:.|..|.|
Zfish     4 DGLPIVGSGVDLTKVPAIQQRRIVAFLNQFIVHTVRFLNRFSTVCEEKLSTVSLRIQQIETTLSI 68

  Fly    67 LEAKLASIPTEHHVATEATEAPAISNQQRNEEASMVDTTEPP------TTENPTEP--ELPPESV 123
            |||||||||....|..|...|||.:|   ...|.....|.||      |...|.||  |.|.|::
Zfish    69 LEAKLASIPGLEEVTVEGVRAPAETN---GPAADTSRATAPPAEASQQTQAAPQEPKTEAPAENI 130

  Fly   124 GVRACEDQRYRKFFKMVQVGVPAPAVKQKMQSEGLEPRILDTPDLILADGQRE 176
             :...:|.||.::.||||||||..|:|.||..|||:|.:|||||..:.|..::
Zfish   131 -MTVAKDPRYARYLKMVQVGVPVMAIKNKMMMEGLDPNLLDTPDAAVPDASKK 182

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CCDC53	NP_609178.1	DUF2360	28..164	CDD:287161	60/143 (42%)
washc3	NP_956467.1	DUF2360	30..170	CDD:287161	60/143 (42%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	87..130		15/45 (33%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	165..200		7/18 (39%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170581352
Domainoid	1	1.000	100	1.000	Domainoid score	I6988
eggNOG	1	0.900	-	-		E1_KOG4496
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H9364
Inparanoid	1	1.050	131	1.000	Inparanoid score	I4617
OMA	1	1.010	-	-		QHG56897
OrthoDB	1	1.010	-	-		D1425330at2759
OrthoFinder	1	1.000	-	-		FOG0006422
OrthoInspector	1	1.000	-	-		oto41542
orthoMCL	1	0.900	-	-		OOG6_105305
Panther	1	1.100	-	-	LDO	PTHR13015
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2443
SonicParanoid	1	1.000	-	-		X6219
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	16	15.800