Protein Alignment Cka and strn4

DIOPT Version :10

• Sequence 1: NP_001245936.1
• Gene: Cka / 34096
• FlyBaseID: FBgn0044323
• Length: 749
• Species: Drosophila melanogaster
• Sequence 2: XP_021321999.2
• Gene: strn4 / 562780
• ZFINID: ZDB-GENE-070501-3
• Length: 768
• Species: Danio rerio
• Alignment Length: 815
• Identity: 336/815 - (41%)
• Similarity: 455/815 - (55%)
• Gaps: 145/815 - (17%)

  Fly    27 GGGVGGANSSIGGVLSNSLGGGGSGGLSISGLNAGGQNANVGGMGNVGGDDGGNGMVGGGVN-NQ 90
            ||..||.:.|          ..|||    :|.|..|..|.:|...:.........|.|...: :|
Zfish     7 GGMAGGTSQS----------PAGSG----TGRNPNGPKAVLGPAPSAVAAAAAGPMAGSSQSRDQ 57

  Fly    91 QATTPQYTIPGILHFIQHEWSRFELERSQWDVDRAELQARIAMLLGERKCLESLKSDLTRRIKML 155
            |......::||||||||:|||||:.|:.:|:.:|.||:|::|.|.||||..|::|.||.||||||
Zfish    58 QDGDAGLSLPGILHFIQYEWSRFQAEKYRWEAERDELRAQVAFLQGERKGQENMKQDLVRRIKML 122

  Fly   156 EYALRQERAKFYRLKYGTDPPQLNEFKPSNEDAGLA-GEVATDSEVPYSSVSNTTWRQGRQMLRQ 219
            ||||:|||||..:||.|||... .|.||..|...:. |...:|||    ..:...|::|||:||:
Zfish   123 EYALKQERAKHQKLKSGTDQSP-GEKKPETEAEPIPNGPANSDSE----PTNQMPWKEGRQLLRK 182

  Fly   220 YLAEIGYTDNIIDVRSNRVRSILGLNNNAEHDGSGG-----------GLGGGLGGGTGGENLSPN 273
            ||.|:||:|.|:|:||.||||:|| .|:.|.:|...           |:||      |||:|...
Zfish   183 YLEEVGYSDTILDMRSKRVRSLLG-RNSPEANGPPSSEPTTEPEPHVGVGG------GGESLLVR 240

  Fly   274 INGNESNKRASETEGRHTPAKKVQQSIDEIIVDTEAAVMANFEFLGATEMSDDDEI--SDDLEMV 336
            ....:..:||    |:.:..:::..|           |:....||...|..|:|:.  .:|.:.:
Zfish   241 QIEEQIKRRA----GKESSKERMGSS-----------VLDKIPFLRGCEDDDEDDSDEEEDFQGM 290

  Fly   337 ATDNDDTDVKLAKRAKSGKDMLTEDL------EADVGEQLLNDMNLMT--EEVDGS--------- 384
            .||..|.......|||.|.:.:|.||      :.|..|..|.:.:.:.  ||.:|:
Zfish   291 TTDCIDGRKNKKSRAKMGGEPMTTDLDPEDEDDEDDSEDALGEFDFLASGEEGEGAGEARISGDG 355

  Fly   385 ---------------------------------------------------------LGLGELAQ 392
                                                                     :.|||||.
Zfish   356 RELGSENRRNKLQGIMSDFPPKPTPPPSIPGQARSGEGGALGFSSDVFILDAVGGGDMNLGELAD 420

  Fly   393 LTVNNESDGAYD-ANSKDGTGGSAGGAGYRKTWNAKYTLRSHFDGVRSLIFHPEEPVLITASEDH 456
            |||.|::|...| .:|::         .::||||.::|||||||.:|:|.|||.:.||::||||.
Zfish   421 LTVANDNDLTIDLQDSRE---------EFKKTWNPRFTLRSHFDAIRALSFHPSQAVLLSASEDG 476

  Fly   457 TLKLWNLQKTVQAKKSASLDVEPLYTFRAHTGPVLCLGMSSSGETCYSGGLDGNIECWQLPSPNI 521
            |||||||.|.:.:||:|:|||||:||||||:|.||.|.|...||:|:||||||.|..|::|..|:
Zfish   477 TLKLWNLNKAMHSKKNAALDVEPIYTFRAHSGAVLSLAMGEEGESCFSGGLDGTIRGWKIPDLNV 541

  Fly   522 DPYDCYDPNVHSGTLEGHTDAVWGLTTMQS--NIVSCSADGTVKLWSPYNKEPLLRTYTASEAEG 584
            ||||.|||.|.|..|.||.||||||....|  .:.||||||||::|.|:|..|.:..:...:..|
Zfish   542 DPYDNYDPGVESSVLSGHEDAVWGLAFSSSLQRLASCSADGTVRIWDPHNSSPCVSVFNKEKEHG 606

  Fly   585 VPSSVDFVRNEVDHIVVAYNSAHCIVYDTETGKQVVRLEAAQEMSGNTGKFINKVVSHPTLPITI 649
            .|:||.||..:...:||:::....::||..|.:.::.|| .|...|:  :.||:|||||:.||:|
Zfish   607 TPTSVAFVNADPSQVVVSFDGGETLLYDLNTEQSIMVLE-TQTKDGS--ELINRVVSHPSQPISI 668

  Fly   650 TAHEDRHIRFWDNTSGTLVHSMVAHLEPVTSLAVDAHGLYLLSGSHDCSIRLWNLDNKTCVQEIT 714
            ||||:|.|||.||.:|.::|||||||:.||.||.|..|.||:|||||||:|||.|||:|||||||
Zfish   669 TAHENRTIRFLDNNTGKVIHSMVAHLDAVTCLATDPKGTYLISGSHDCSVRLWMLDNRTCVQEIT 733

  Fly   715 AHRKKFDESIFDVAFHATKPYIASAGADGLAKVFV 749
            |||||.||:|.|||||.|:|:|||||||.|||:||
Zfish   734 AHRKKHDEAIHDVAFHPTQPFIASAGADALAKIFV 768

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cka	NP_001245936.1	Striatin	99..228	CDD:462401	68/129 (53%)
		WD40	429..748	CDD:238121	185/320 (58%)
		WD40 repeat	439..485	CDD:293791	29/45 (64%)
		WD40 repeat	491..538	CDD:293791	26/46 (57%)
		WD40 repeat	543..578	CDD:293791	17/36 (47%)
		WD40 repeat	587..629	CDD:293791	12/41 (29%)
		WD40 repeat	636..672	CDD:293791	23/35 (66%)
		WD40 repeat	678..717	CDD:293791	29/38 (76%)
		WD40 repeat	724..748	CDD:293791	18/23 (78%)
strn4	XP_021321999.2	None