Protein Alignment Cka and Cka

DIOPT Version :10

• Sequence 1: NP_001245936.1
• Gene: Cka / 34096
• FlyBaseID: FBgn0044323
• Length: 749
• Species: Drosophila melanogaster
• Sequence 2: XP_061518587.1
• Gene: Cka / 4578045
• VectorBaseID: AGAMI1_008554
• Length: 762
• Species: Anopheles gambiae
• Alignment Length: 794
• Identity: 496/794 - (62%)
• Similarity: 589/794 - (74%)
• Gaps: 99/794 - (12%)

  Fly    12 NNKPVGGATGAGVLVG--GGVGGANSSIGGVLSNSLGGGGSGGL-SISGLNAGGQNANVGGMGNV 73
            :|..:|...|.|..||  ||:||...  ||      .|||:||| .:||  .||..:.:.|.|..
Mosquito    12 DNSSLGHQNGGGSAVGQLGGIGGGAG--GG------QGGGTGGLGDMSG--GGGAGSGLVGKGGA 66

  Fly    74 GGDDGGNGMVGGG-VNNQQATTP-QYTIPGILHFIQHEWSRFELERSQWDVDRAELQARIAMLLG 136
            ||  ||.||||.| .::|...|| ||:||||||||||||:||||||||||||||||||:||:|:|
Mosquito    67 GG--GGGGMVGAGQCDDQNNKTPTQYSIPGILHFIQHEWARFELERSQWDVDRAELQAKIAVLVG 129

  Fly   137 ERKCLESLKSDLTRRIKMLEYALRQERAKFYRLKYGTDPPQLNEFKPSNEDAGLAGEVATDSEVP 201
            |||..|||||||.||||||||||:||||||:|||||.||| :|:.||..::.|:..|||.|.|||
Mosquito   130 ERKGQESLKSDLIRRIKMLEYALKQERAKFHRLKYGVDPP-MNDIKPPTDEPGIGTEVAPDPEVP 193

  Fly   202 YSSVSNTTWRQGRQMLRQYLAEIGYTDNIIDVRSNRVRSILGLNNNAEHDGSGGGLGGGLGGGTG 266
            ||||||.||||||.:|||||.||||||.|:|:|||||||:||||||:|.:
Mosquito   194 YSSVSNITWRQGRLLLRQYLQEIGYTDTILDIRSNRVRSLLGLNNNSEQE--------------- 243

  Fly   267 GENLSPNIN-GNESNKRASETEGRHTPAKKVQQSIDEIIVDTEAAVMANFEFLGA--TEMSDDDE 328
             ||::||:| |.||||||||::||.|||||.....:.:|:|:||||:||||||..  .||||||:
Mosquito   244 -ENVNPNVNGGTESNKRASESQGRRTPAKKPSSVTEAMILDSEAAVIANFEFLAREDVEMSDDDD 307

  Fly   329 ISDDLEMVATDNDDTDVKLAKRAKSGKDMLTEDLEADVGEQLLNDMNLMT--------------- 378
            :||::::|. |::|||:|..||...| ..|.:|::|: .::::|::|.:|
Mosquito   308 VSDEIDVVG-DSEDTDMKTTKRKAKG-STLNDDMDAE-ADEVINELNPLTEGEDVIMAQDKGSIS 369

  Fly   379 ------------------------------EEVDGSLGLGELAQLTVNNESDGAYD-ANSKDGTG 412
                                          ||||.|  ||||||||||||::..|| :|||:
Mosquito   370 EVDVAGDDLYGGYNKTGMPRHPTIPGIGNDEEVDSS--LGELAQLTVNNETESGYDVSNSKE--- 429

  Fly   413 GSAGGAGYRKTWNAKYTLRSHFDGVRSLIFHPEEPVLITASEDHTLKLWNLQKTVQAKKSASLDV 477
                  .|||||||||||||||||||:|.|||:||||||||||||||||||||||.|||||||||
Mosquito   430 ------PYRKTWNAKYTLRSHFDGVRALAFHPQEPVLITASEDHTLKLWNLQKTVPAKKSASLDV 488

  Fly   478 EPLYTFRAHTGPVLCLGMSSSGETCYSGGLDGNIECWQLPSPNIDPYDCYDPNVHSGTLEGHTDA 542
            |||||||:|:||||||.||::||.||||||||.|.||.|||.||||||.|||.|...|::|||||
Mosquito   489 EPLYTFRSHSGPVLCLAMSATGEQCYSGGLDGAINCWNLPSSNIDPYDSYDPEVMRCTIDGHTDA 553

  Fly   543 VWGLTT--MQSNIVSCSADGTVKLWSPYNKEPLLRTYTASEAEGVPSSVDFVRNEVDHIVVAYNS 605
            ||||..  .::.:||||||||||||||..|.|...|...||.||||:|||||::::|.|||||:|
Mosquito   554 VWGLAVNHAKNTLVSCSADGTVKLWSPSGKIPTNSTTFTSETEGVPTSVDFVKDQIDRIVVAYSS 618

  Fly   606 AHCIVYDTETGKQVVRLEAAQEMSGNTGKFINKVVSHPTLPITITAHEDRHIRFWDNTSGTLVHS 670
            .|||:||||||||||:|||:|||:||.||.||||:||||||:|||||||||||||||.:|:||||
Mosquito   619 THCIIYDTETGKQVVKLEASQEMTGNLGKHINKVISHPTLPVTITAHEDRHIRFWDNGTGSLVHS 683

  Fly   671 MVAHLEPVTSLAVDAHGLYLLSGSHDCSIRLWNLDNKTCVQEITAHRKKFDESIFDVAFHATKPY 735
            |||||:.|||||:|||||||||||||||||||::||||||||||||||||||||.|||||.:||:
Mosquito   684 MVAHLDAVTSLAIDAHGLYLLSGSHDCSIRLWHMDNKTCVQEITAHRKKFDESILDVAFHPSKPF 748

  Fly   736 IASAGADGLAKVFV 749
            |||||||.:|||||
Mosquito   749 IASAGADAIAKVFV 762

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cka	NP_001245936.1	Striatin	99..228	CDD:462401	100/128 (78%)
		WD40	429..748	CDD:238121	250/320 (78%)
		WD40 repeat	439..485	CDD:293791	41/45 (91%)
		WD40 repeat	491..538	CDD:293791	32/46 (70%)
		WD40 repeat	543..578	CDD:293791	21/36 (58%)
		WD40 repeat	587..629	CDD:293791	30/41 (73%)
		WD40 repeat	636..672	CDD:293791	30/35 (86%)
		WD40 repeat	678..717	CDD:293791	35/38 (92%)
		WD40 repeat	724..748	CDD:293791	17/23 (74%)
Cka	XP_061518587.1	None