DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG7367 and Pnlip

DIOPT Version :9

Sequence 1:	NP_609175.2	Gene:	CG7367 / 34094	FlyBaseID:	FBgn0031976	Length:	389	Species:	Drosophila melanogaster
Sequence 2:	NP_081201.2	Gene:	Pnlip / 69060	MGIID:	97722	Length:	465	Species:	Mus musculus

Alignment Length:	336	Identity:	111/336 - (33%)
Similarity:	157/336 - (46%)	Gaps:	85/336 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly    85 PENRINLPQLIKFELYGSDSSSSADFWIDENNFEFPQRHKRDTWQEMAEKFNPELDTKILVHG-- 147
            |:|         ::|..||:|:     |..:||...::                  |:|::||
Mouse    63 PDN---------YQLITSDASN-----IRNSNFRTNRK------------------TRIIIHGFI 95

  Fly   148 ------WKSSTMSNSIQSIRGAYIERGQVNVFAINWKDQADNIYYLTPARYTVQ-VGRAVAKLID 205
                  |.|....|..:      :|  .||...::||..:...|  |.|...|: ||..||.|::
Mouse    96 DKGEENWLSDMCKNMFR------VE--SVNCICVDWKGGSRTTY--TQATQNVRVVGAEVALLVN 150

  Fly   206 LLVEEKDADPNRIHLIGHSLGAHIMGYAGSYTKYRVNRITGLDPARPAFEDCIGPEN-HLDDTDA 269
            :|..:.....|.:||||||||:||.|.||..|...:.||||||||.|.|:..  ||. .||.|||
Mouse   151 VLQSDLGYSLNNVHLIGHSLGSHIAGEAGKRTFGAIGRITGLDPAEPYFQGT--PEEVRLDPTDA 213

  Fly   270 NFVDVIHSCAGYL------GFRKPIGMVDFYPNGGGPPQPGCKE--LSQI------------FTG 314
            .|||.||:.||.:      |..:.:|.:||:|| ||...|||::  ||||            |..
Mouse   214 QFVDAIHTDAGPIIPNLGFGMSQTVGHLDFFPN-GGIEMPGCQKNILSQIVDIDGIWEGTRNFAA 277

  Fly   315 CSHGRSYEYYAESINSPKGFYGVPCSGLDELKGKNC----TGGKILMG---DPVPREARGI---F 369
            |:|.|||::|.:||.:|.||.|..||.........|    :||...||   |..|.:...:   |
Mouse   278 CNHLRSYKFYTDSIVNPTGFAGFSCSSYSLFTANKCFPCGSGGCPQMGHYADRYPGKTSRLYQTF 342

  Fly   370 FVKTANKPSYA 380
            ::.|.:|.::|
Mouse   343 YLNTGDKSNFA 353

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7367	NP_609175.2	Pancreat_lipase_like	115..374	CDD:238363	101/298 (34%)
Pnlip	NP_081201.2	Lipase	18..352	CDD:278576	110/333 (33%)
		Pancreat_lipase_like	51..348	CDD:238363	109/329 (33%)
		PLAT_PL	355..465	CDD:238857
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167835312
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_28N19
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11610
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.840