DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG7367 and PNLIPRP3

DIOPT Version :9

Sequence 1:	NP_609175.2	Gene:	CG7367 / 34094	FlyBaseID:	FBgn0031976	Length:	389	Species:	Drosophila melanogaster
Sequence 2:	NP_001011709.2	Gene:	PNLIPRP3 / 119548	HGNCID:	23492	Length:	467	Species:	Homo sapiens

Alignment Length:	268	Identity:	94/268 - (35%)
Similarity:	132/268 - (49%)	Gaps:	57/268 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly   123 HKRDTWQEM---------AEKFNPELDTKILVHGWKSS-----TMSNSIQSIRGAYIERGQVNVF 173
            |..:.:||:         |..|..:..|:|.:.|||:.     .|.|.:       ::...:|..
Human    62 HNPNAYQEISAVNSSTIQASYFGTDKITRINIAGWKTDGKWQRDMCNVL-------LQLEDINCI 119

  Fly   174 AINW-KDQADNIYYLTPARYTVQVGRAVAKLIDLLVEEKDADPNRIHLIGHSLGAHIMGYAGSYT 237
            .::| ....:.|:.:...|.   ||..||..||:|:::.:..|:::||||||||||:.|.|||
Human   120 NLDWINGSREYIHAVNNLRV---VGAEVAYFIDVLMKKFEYSPSKVHLIGHSLGAHLAGEAGS-- 179

  Fly   238 KYRV---NRITGLDPARPAFEDCIGPENHLDDTDANFVDVIHSCAGYLGFRKPIGMV------DF 293
              |:   .||||||||.|.|.: ...|..||.:|||||||||:.|..:.|...:|.:      ||
Human   180 --RIPGLGRITGLDPAGPFFHN-TPKEVRLDPSDANFVDVIHTNAARILFELGVGTIDACGHLDF 241

  Fly   294 YPNGGGPPQPGC----------------KELSQIFTGCSHGRSYEYYAESINSPKGFYGVPCSGL 342
            ||| ||...|||                ||::..| .|:|.|||::|||||.:|..|...||...
Human   242 YPN-GGKHMPGCEDLITPLLKFNFNAYKKEMASFF-DCNHARSYQFYAESILNPDAFIAYPCRSY 304

  Fly   343 DELKGKNC 350
            ...|..||
Human   305 TSFKAGNC 312

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7367	NP_609175.2	Pancreat_lipase_like	115..374	CDD:238363	94/268 (35%)
PNLIPRP3	NP_001011709.2	Lipase	18..352	CDD:278576	94/268 (35%)
		Pancreat_lipase_like	52..348	CDD:238363	94/268 (35%)
		PLAT_PL	355..467	CDD:238857
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165145200
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_28N19
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11610
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	4	3.840