Protein Alignment Tg and tgm3l.8

DIOPT Version :10

• Sequence 1: NP_609174.1
• Gene: Tg / 34093
• FlyBaseID: FBgn0031975
• Length: 776
• Species: Drosophila melanogaster
• Sequence 2: XP_002935578.1
• Gene: tgm3l.8 / 594880
• XenbaseID: XB-GENE-5955394
• Length: 694
• Species: Xenopus tropicalis
• Alignment Length: 714
• Identity: 223/714 - (31%)
• Similarity: 357/714 - (50%)
• Gaps: 57/714 - (7%)

  Fly    52 AVLGVLKVDLCLEDNHEEHHTSHFYAAAAKEALVVRRGEPFRLKIHFNR-DYSPSKDAISFIFTV 115
            :.|.:..::|....|...||||.|.:.    ...:|||:|..:.::||| .|:....||..
 Frog     2 SALQLKSINLQKATNVANHHTSGFDST----VFALRRGQPITVNLNFNRVFYTGESVAIDV---- 58

  Fly   116 ADDTKPSPG-HGTLNALVPHDGIDYLGDTLEWGAGIESHEGQTLTVLIKPPSTCPVTEWKLDIDT 179
              :|.|||. .....|::|   :....:...|.|......|.|:.|:|..|.......:|:....
 Frog    59 --ETGPSPSVPKNTKAVMP---VSKYANPQTWSASSGQSTGATMPVIINIPVNAIPGRYKMTAHL 118

  Fly   180 KLLGDGSRSYPLPLPIYVLFNPWCPDDQVYLEDRDQRKEYVMHDTTLIWRGSYNRLRPSVWKIGQ 244
            ...|..:.||.|| ..:||||||..|||||:.:..:|.|||:::..:|:||:.|.:....|...|
 Frog   119 ARSGRTTASYRLP-EFFVLFNPWNQDDQVYMSNEAERNEYVLNEYGVIFRGNANNISRLAWDYAQ 182

  Fly   245 FERHVLECSLKVLGTV--GRIPP----AYRGDPVRVARALSALVNSVDDDGVLLGNWSEDFSGGV 303
            ||..:|:....:|.:.  .:..|    :.|.||:.|.|.|||:||..||:|||.|.|..|:|.||
 Frog   183 FEGDMLDICFLMLDSCLEHKTDPITDISNRYDPIYVGRVLSAIVNINDDNGVLYGRWDNDYSDGV 247

  Fly   304 APTKWTGSVEILQQFYKTQKSVKFAQCWNFSGVLTTIARSLGIPSRIITCYSSAHDTQASLTVDV 368
            :||.|:||..||:. ::....||:.|||.|:|||.|:.|.||||:|:|:.:.||||..::|.::.
 Frog   248 SPTSWSGSARILRS-WRDNGPVKYGQCWVFAGVLCTVLRCLGIPARVISNFESAHDGNSNLLIEE 311

  Fly   369 FIDANNKKLDAETTDSIWNYHVWNELWMQRPDLGVGEHGTFDGWQVVDATPQEASDNMYRVGPAS 433
            :.|....:|.  :.||:||:|.|||.|..|.|||    ..:.|||::|:||||.|..:|.:||.|
 Frog   312 YFDEKGTQLG--SPDSVWNFHCWNEAWFTRGDLG----DNYGGWQILDSTPQEPSGGIYCLGPTS 370

  Fly   434 VAAVKNGDILRPFDGGFVFAEVNAD-KLYWRYNGPSQPLKLLRKDTLAIGHLISTKAVLKWERED 497
            :.|||.||:...:|..|||.|||:| |.:.:|: ..:||:.:..||.::|..||||||....|:|
 Frog   371 LKAVKQGDVTLDYDTTFVFGEVNSDRKRFIKYS-DGRPLQNVYTDTASVGQFISTKAVGSNNRQD 434

  Fly   498 ITDTYKHAERSEEERSTMLKA----LKQSRHAFSRYYLNDNFN----DIEFDMELKDDIKIGQSF 554
            :|:.||..|.|.:||.|..||    |.......:...:.:...    :|....:|....:||...
 Frog   435 VTNGYKDPEGSGKERETFNKARTTLLSLGIATMAARSVQEEPKGPKPEITGSFKLSGQPQIGDDV 499

  Fly   555 SVVLKVSNKSESRTHMATGQISCDAVLYTGVGAVEVKTLGFELELEPKSSDYVRMEVIFEEYYDK 619
            .|:..:.|.:.:|.::.. :.:..|::|....:.|:.|....:.|.....:.|.:.|.:.:|...
 Frog   500 VVIFNIKNPTSARKNIKL-KFTVTAIVYNRAVSKEILTNNQPVTLAANKEESVNLTVEYSKYQGA 563

  Fly   620 LSSQAAFQISA-------AAKVKDTDYDYYAQDDFRVRKPDIKFQLGEAAIVAQKELDVILRLEN 677
            |:.....|:.|       ||.:.||        ...::.|.::.::.:.|.| .|.|.|.:..:|
 Frog   564 LTPDNMIQVVAVCEEENGAALLTDT--------VITLKNPPMQLKVPDKAAV-NKALSVEVIFQN 619

  Fly   678 PLPIPLHKGVFTVEGPG-IEQPLKFKIAEIPVGGTAAATFKYTPPYAGRGTMLAKFTSKELDDV 740
            .:...|...:.|:||.| |:..:|..:.::......:.....||..:|...:.|..::.:|.||
 Frog   620 TIGDRLKNCLITLEGSGLIKDEVKVPVPDLKPSEKYSTKVVITPYKSGERNLSANLSADKLSDV 683

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tg	NP_609174.1	Transglut_N	58..180	CDD:459971	31/123 (25%)
		TGc	324..419	CDD:214673	41/94 (44%)
		Transglut_C	538..644	CDD:460002	22/112 (20%)
		Transglut_C	652..750	CDD:460002	21/90 (23%)
tgm3l.8	XP_002935578.1	Transglut_N	7..117	CDD:459971	31/122 (25%)
		TGc	267..356	CDD:214673	41/94 (44%)
		Transglut_C	483..574	CDD:460002	17/91 (19%)
		Transglut_C	595..693	CDD:460002	21/90 (23%)