Protein Alignment Tg and f13a1a.2

DIOPT Version :10

• Sequence 1: NP_609174.1
• Gene: Tg / 34093
• FlyBaseID: FBgn0031975
• Length: 776
• Species: Drosophila melanogaster
• Sequence 2: XP_686649.6
• Gene: f13a1a.2 / 558353
• ZFINID: ZDB-GENE-120307-1
• Length: 744
• Species: Danio rerio
• Alignment Length: 740
• Identity: 231/740 - (31%)
• Similarity: 371/740 - (50%)
• Gaps: 27/740 - (3%)

  Fly    14 WKWCTSKDNEESTLRIRN--ANANYFTGIPQGDKTDGASSAVLGVLKVDLCLEDNHEEHHTSHFY 76
            |:|......::|.....|  .:..:.|..|:|...:...:|.|.||.:|:.:.:|...|||..:.
Zfish    12 WRWGARAIIDKSNSLESNPPPHEKFPTVSPRGPTDEAIRAASLSVLSIDMRVTENKNVHHTDTYK 76

  Fly    77 AAAAKEALVVRRGEPFRLKIHFNRDYSPSKDAISFIFTVADDTKPSPGHGTLNALVPHDGIDYLG 141
            .:    .|:|||...|.:.:..:|.::..:..:...|.:.  :.|....||.  ::...|.:...
Zfish    77 GS----NLIVRRNTEFTIILKLDRAFNEQQHQVELEFLIG--SSPDENKGTY--IIVSIGKEKQD 133

  Fly   142 DTLEWGAGIESHEGQTLTVLIKPPSTCPVTEWKL-DIDTKLLGDGSRSYPLPLPIYVLFNPWCPD 205
            .:  |.:.:.:..|.::.|.|.|.:.|.:..::: .:...:||............|||||||..:
Zfish   134 SS--WKSRVVAMHGNSVMVGITPDAKCIIGRFRIFAVVVSVLGKERTQRNPDTDFYVLFNPWNSE 196

  Fly   206 DQVYLEDRDQRKEYVMHDTTLIWRGSYNRLRPSVWKIGQFERHVLECSLKVLGTVGRIPPAYRGD 270
            |:||::..:.|:||||::...|:.|.:|.:....|..||||..||:..|.|: ..|.:|..:||:
Zfish   197 DEVYMDKEEDRQEYVMNEVGTIYNGVHNNITTRSWNFGQFEEGVLDACLTVM-DAGNVPLLFRGN 260

  Fly   271 PVRVARALSALVNSVDDDGVLLGNWSEDFSGGVAPTKWTGSVEILQQFYKTQKSVK--FAQCWNF 333
            ...|.|..|||:||..|:|||:|:||.|:|.|.|||.||||.|||.: |.::..|.  |||||.|
Zfish   261 ATEVVRQASALMNSQGDNGVLVGSWSGDYSSGTAPTAWTGSPEILLK-YASEGCVPVCFAQCWVF 324

  Fly   334 SGVLTTIARSLGIPSRIITCYSSAHDTQASLTVDVFIDANNKKLDAETTDSIWNYHVWNELWMQR 398
            :|.|.|..|.||||.|::|.|.||||...:|..|:.:|.:.:...:.|.||:||||.|||::|:|
Zfish   325 AGTLNTFVRCLGIPGRVVTNYCSAHDNTGNLKTDIVLDEDGRMDKSRTRDSVWNYHCWNEVFMKR 389

  Fly   399 PDLGVGEHGTFDGWQVVDATPQEASDNMYRVGPASVAAVKNGDILRPFDGGFVFAEVNADKLYWR 463
            .||    ...:.||||||.||||.||.::|.||.||.|:|.|::..|||..|||||:|:|.:|.:
Zfish   390 LDL----PDQYSGWQVVDCTPQETSDGLFRCGPTSVNAIKEGELSYPFDARFVFAELNSDVIYHK 450

  Fly   464 YNGPSQPLKLLRKDTLAIGHLISTKAVLKWEREDITDTYKHAERSEEERSTMLKALKQSRHAFSR 528
            .|...: .|::..||..:|..:.||.....:..|||.:||::|.|.:||..|..|  :.|...||
Zfish   451 SNKYGK-TKIIHVDTSYVGKQLVTKKHDSNDYMDITSSYKYSEASLKERQVMQMA--ERRGVPSR 512

  Fly   529 YYLNDNFNDIEFDMELKDDIKIGQSFSVVLKVSNKSESRTHMATGQISCDAVLYTGVGAVEVKTL 593
            .||......:|..:: .:.||||..|.:.:.:.|||.....:......| .|.|||:...:.|..
Zfish   513 KYLTLPEAGVEIQIQ-TNTIKIGDDFRLTMNIKNKSSKACTVIATVTGC-VVFYTGITGSDFKLE 575

  Fly   594 GFELELEPKSSDYVRMEVIFEEYYDKLSSQAAFQISAAAKVKDTDYDYYAQDDFRVRKPDIKFQL 658
            ..:..::...::.|.:::...:|...|..||.........|::|:..........::.|::..::
Zfish   576 NKKASVQASKTEPVTIDIKAVDYTPHLVEQANLLFVVYGIVEETETPLTTMRVINLQLPELTIKM 640

  Fly   659 GEAAIVAQKELDVILRLENPLPIPLHKGVFTVEGPGIEQPLKFKIAEIPVGGTAAATFKYTPPYA 723
            ..:..|. .:|.|.:...||...||.|....::|||:.|......::|..|.:...|....|...
Zfish   641 SGSPRVG-SDLLVSVEFTNPYNFPLLKVELRLDGPGLIQTKVKHYSQILPGASVNYTVSIVPRAH 704

  Fly   724 GRGTMLAKFTSKELDDVDGYRHYEI 748
            |:..::|......|..|.....:|:
Zfish   705 GKKVLMACLDCSALRQVTNQLEFEV 729

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tg	NP_609174.1	Transglut_N	58..180	CDD:459971	22/122 (18%)
		TGc	324..419	CDD:214673	45/96 (47%)
		Transglut_C	538..644	CDD:460002	22/105 (21%)
		Transglut_C	652..750	CDD:460002	22/97 (23%)
f13a1a.2	XP_686649.6	None