Protein Alignment Tg and tgm1l6

DIOPT Version :10

• Sequence 1: NP_609174.1
• Gene: Tg / 34093
• FlyBaseID: FBgn0031975
• Length: 776
• Species: Drosophila melanogaster
• Sequence 2: XP_021325715.1
• Gene: tgm1l6 / 334438
• ZFINID: ZDB-GENE-030131-6370
• Length: 820
• Species: Danio rerio
• Alignment Length: 768
• Identity: 255/768 - (33%)
• Similarity: 383/768 - (49%)
• Gaps: 85/768 - (11%)

  Fly    11 CGDWKW--CTSKDNEESTLRIRNANANYFTGIPQGDKTDGASSAVLGVLKVDL--C-LEDNHEEH 70
            |.|:|.  ...||.::.::               ..:..|.:..:|.|:|:||  | ...|.:||
Zfish   107 CHDYKTKEVIIKDYKDESI---------------SKQVSGGNVDLLRVIKIDLLKCKTGPNRQEH 156

  Fly    71 HTSHFYAAAAKEALVVRRGEPFRLKIHFNRDYSPSKDAISFIFTVADDTKPSPGHGTLNALVP-- 133
            ||..|:    .|.|:||||:.|.:.:...|.::|:.|.:.....:        ||      :|
Zfish   157 HTHFFH----DEQLIVRRGQSFNMWVDLCRPFNPASDKLHLELRL--------GH------IPSI 203

  Fly   134 HDGIDYLGDTLE------WGAGIESHEGQTLTVLIKPPSTCPVTEWKLDIDTKLLGDGSRSYPLP 192
            .||...:...:|      |||.|..|....:.:.:...||..|..::|.:.|:..   :..:.||
Zfish   204 RDGTYVIVPIVEEFKKDCWGAKIVEHGQNRIKLCVNSLSTACVGRYQLSVVTQCT---AGKFTLP 265

  Fly   193 -LP---IYVLFNPWCPDDQVYLEDRDQRKEYVMHDTTLIWRGSYNRLRPSVWKIGQFERHVLECS 253
             :|   ||:||||||.:|.|||.|:.:|.|||::|...|:.|:..::....|..||||..:|...
Zfish   266 YVPEHDIYMLFNPWCKEDSVYLSDQAERTEYVLNDMGKIYYGTKQQIGCKTWNFGQFEDGILPAC 330

  Fly   254 LKVLGTVGRIPPAYRGDPVRVARALSALVNSVDDDGVLLGNWSEDFSGGVAPTKWTGSVEILQQF 318
            ..||...| .|.:..|:|:.::|.:|.::|:..|.|||:.|||..:..|.|||.|:.|..||:|:
Zfish   331 FYVLEKSG-TPCSGWGNPINISRVVSEMINANKDRGVLIANWSNYYVDGTAPTLWSSSSAILKQY 394

  Fly   319 YKT-QKSVKFAQCWNFSGVLTTIARSLGIPSRIITCYSSAHDTQASLTVDVFIDANNKKLDAETT 382
            :|. ...||:.|...|:||..|:.|.||||:|.||.:.|||||..|||.||::|...:.:|....
Zfish   395 HKCGGVPVKYGQSLAFAGVTNTMLRCLGIPARPITNFCSAHDTDVSLTTDVYLDEKFQLIDQMNR 459

  Fly   383 DSIWNYHVWNELWMQRPDLGVGEHGTFDGWQVVDATPQEASDNMYRVGPASVAAVKNGDILRPFD 447
            |||||||||||.||.||||..|    |.|||.:|:|||:.....:|.||.||||:::|......|
Zfish   460 DSIWNYHVWNEAWMTRPDLPTG----FGGWQAIDSTPQQTHQGFFRCGPTSVAAIRSGQTFLKHD 520

  Fly   448 GGFVFAEVNADKLYW-RYNGPSQPLKLLRKDTLAIGHLISTKAVLKWEREDITDTYKHAERSEEE 511
            ..|:|||||:||:|| |.|..:..:..:.||  .:||.||||||...:|.|||:.|||...||:.
Zfish   521 VPFLFAEVNSDKVYWQRKNNGTFGVVHVEKD--VVGHCISTKAVGSDQRVDITNLYKHPCGSEDR 583

  Fly   512 RSTMLKALKQSRHAFSRYYLNDNF---NDIEFDMELK-DDIKIGQSFSVVLKVSNK-SESR---- 567
            .:.:..||   ||...|  |....   .|:..::.|| |...:|:...:.:.:.|| ::.|
Zfish   584 LTALETAL---RHGCKR--LTHPLPIPEDVICEVNLKGDGPLVGKDAVLSINLKNKCNQPRSITL 643

  Fly   568 -THMATGQISCDAVLYTGVGAVEVKTLGFELELEPKSSDYVRMEVIFEEYYDKLSSQAAFQISAA 631
             :|.|       |:.||||....:|.....:||:...|..:...:.::||.:.|...|...::..
Zfish   644 YSHAA-------AMYYTGVRRTYLKRDQTSIELKASESKLLEWTLSYDEYKEHLVDHAPLMLNLF 701

  Fly   632 AKVKDTDYDYYAQDDFRVRKPDIKFQLGEAAIVAQKELDVILRLENPLPIPLHKGVFTVEGPGIE 696
            ..|..|......|.:||:|.||:.......|:|.| |:.|.:..:|||...|...||...|.|::
Zfish   702 GHVAQTKQILATQYNFRLRTPDLVLAPVCDAVVGQ-EVAVKVTFQNPLSCVLKNSVFRFVGLGLK 765

  Fly   697 QPLKFKIAEIPVGGTAAATFKYTPPYAGRGTMLAKFTSKELDDVDGYRHYEIE 749
            |.......:|....|.:.|.|:.|...|...:||.|...:|..|.|:.:..::
Zfish   766 QARVINYGDIAGHATVSLTEKFIPMCHGPQKLLASFDCPQLTQVHGFTNMVVK 818

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tg	NP_609174.1	Transglut_N	58..180	CDD:459971	35/132 (27%)
		TGc	324..419	CDD:214673	50/94 (53%)
		Transglut_C	538..644	CDD:460002	24/112 (21%)
		Transglut_C	652..750	CDD:460002	28/98 (29%)
tgm1l6	XP_021325715.1	Transglut_N	141..256	CDD:459971	35/132 (27%)
		TGc	401..492	CDD:214673	50/94 (53%)
		Transglut_C	616..714	CDD:460002	22/104 (21%)
		Transglut_C	731..819	CDD:460002	26/89 (29%)