Protein Alignment Tg and tgm3l.7

DIOPT Version :10

• Sequence 1: NP_609174.1
• Gene: Tg / 34093
• FlyBaseID: FBgn0031975
• Length: 776
• Species: Drosophila melanogaster
• Sequence 2: XP_031750709.1
• Gene: tgm3l.7 / 100498415
• XenbaseID: XB-GENE-22168652
• Length: 703
• Species: Xenopus tropicalis
• Alignment Length: 726
• Identity: 232/726 - (31%)
• Similarity: 370/726 - (50%)
• Gaps: 63/726 - (8%)

  Fly    56 VLK-VDLCLEDNHEEHHTSHFYAAAAKEALVVRRGEPFRLKIHFNRDYSPSKDAISFIFTVADDT 119
            ||| :||..:.|...|:||.:    ..:..:||||.|.::.:.|:|... |.::::.:.    :|
 Frog     5 VLKSIDLQQKSNAAAHNTSDY----VSKVPIVRRGLPMKVTLAFSRALQ-STESLALVM----ET 60

  Fly   120 KPSPGHGTLNALVPHDGIDYLGDTLEWGAGIESHEGQTLTVLIKPPSTCPVTEWKLDIDTKLLGD 184
            .|||...|...:|.........||  |.|.:||....|:||.|..|....:..:|  |..::...
 Frog    61 GPSPSASTNTRIVMPVSSSRRNDT--WSATLESSSAGTMTVSINIPVNASIGPYK--ITAQITSA 121

  Fly   185 GSRSYPLPLPIYVLFNPWCPDDQVYLEDRDQRKEYVMHDTTLIWRGSYNRLRPSVWKIGQFERHV 249
            |..|........||||.|...|:.|:.:..:|||||:::|.|::.||......|.|..|.||..|
 Frog   122 GRTSTNDVGRCSVLFNAWASGDEAYMSNDAERKEYVLNETGLVFYGSAGFPSSSAWDYGHFEDGV 186

  Fly   250 LECSLKVLGTVGRIPPAYR----------GDPVRVARALSALVNSVDDDGVLLGNWSEDFSGGVA 304
            ::...|:|    :..|.|:          .|||.::|.|||:|||.||.||::||||.|:|||..
 Frog   187 VDICFKLL----QESPEYKADPATHISKCNDPVYISRILSAMVNSQDDRGVIVGNWSGDYSGGEN 247

  Fly   305 PTKWTGSVEILQQFYKTQKSVKFAQCWNFSGVLTTIARSLGIPSRIITCYSSAHDTQASLTVDVF 369
            |:.|:|||.:||: :.....|::.|||.::|||.|..|.||:.:|:||.:.|||||..:|.::.:
 Frog   248 PSSWSGSVALLQR-WSQSGPVRYGQCWVYAGVLCTTLRCLGLAARLITNFESAHDTNNNLIIEQY 311

  Fly   370 IDANNKKLDAETTDSIWNYHVWNELWMQRPDLGVGEHGTFDGWQVVDATPQEASDNMYRVGPASV 434
            :||..:.:.  :.||:||:|.|.|.|.:|.|||    .|:||||::||||||.|...||:||.|.
 Frog   312 LDAYGRSIG--SPDSVWNFHAWVECWFRRKDLG----STYDGWQILDATPQEPSGGSYRLGPTSQ 370

  Fly   435 AAVKNGDILRPFDGGFVFAEVNADKLYW--RYNGPSQPLKLLRKDTLAIGHLISTKAVLKWERED 497
            .|||.||:..||||.||.||||||::|:  |.:|   ...:|..||..:|..||||||..:.|:|
 Frog   371 KAVKLGDVNLPFDGPFVLAEVNADEIYYGRRNDG---TFSILYTDTRKVGQYISTKAVGNFSRQD 432

  Fly   498 ITDTYKHAERSEEERSTMLKA----LKQSRHAFSRYYLNDNFNDIEFD---------------ME 543
            :||.||..|.|:|||.::.||    .:..|...:...||.....:..|               .:
 Frog   433 VTDQYKFPEGSKEERDSLHKAQGLTARSDRVMLASRRLNATAARVVEDKPPIQEAPKPEIIGTFK 497

  Fly   544 LKDDIKIGQSFSVVLKVSNKSESRTHMATGQISCDAVLYTGVGAVEVKTLGFELELEPKSSDYVR 608
            |..::::||.|:|.|.:.|.:.|:..: ..:.:..|::|......|:.:....:.|.|.....:.
 Frog   498 LSGELQVGQDFTVTLNLKNPTSSKKQV-NAKWTLTAIVYNRTPVKEILSDSQSVTLAPNEEKVIE 561

  Fly   609 MEVIFEEYYDKLSSQAAFQISAAAKVKDTDYDYYAQDDFRVRKPDIKFQLGEAAIVAQKELDVIL 673
            :.|::.:|...|:.....:.||.. |::............::.|.::....| .:...|...:.:
 Frog   562 ITVLYPQYEKALTPDNMIRASAVC-VEENGGSLLVDKVITLKNPPLQITAPE-RVTWGKSATLGI 624

  Fly   674 RLENPLPIPLHKGVFTVEGPGI-EQPLKFKIAEIPVGGTAAATFKYTPPYAGRGTMLAKFTSKEL 737
            ...||:...:...|.|::|.|| ::.||..:.::.......|..:.||...|:..::|.|:..:.
 Frog   625 VFTNPISEDIKNCVVTLQGSGILKKTLKVPLPDLKANQRIRAEAEVTPYRNGKRVVIAGFSCDKF 689

  Fly   738 DDVDGYRHYEI 748
            .||.||:..::
 Frog   690 SDVKGYQTVDV 700

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tg	NP_609174.1	Transglut_N	58..180	CDD:459971	34/122 (28%)
		TGc	324..419	CDD:214673	41/94 (44%)
		Transglut_C	538..644	CDD:460002	20/120 (17%)
		Transglut_C	652..750	CDD:460002	22/98 (22%)
tgm3l.7	XP_031750709.1	Transglut_N	7..118	CDD:459971	34/123 (28%)
		TGc	266..355	CDD:214673	41/94 (44%)
		Transglut_C	492..>569	CDD:460002	14/77 (18%)
		Transglut_C	604..702	CDD:460002	22/98 (22%)