Protein Alignment Spn28Dc and SERPINB12

DIOPT Version :9

• Sequence 1: NP_609172.1
• Gene: Spn28Dc / 34091
• FlyBaseID: FBgn0031973
• Length: 536
• Species: Drosophila melanogaster
• Sequence 2: XP_005266835.2
• Gene: SERPINB12 / 89777
• HGNCID: 14220
• Length: 437
• Species: Homo sapiens
• Alignment Length: 486
• Identity: 116/486 - (23%)
• Similarity: 204/486 - (41%)
• Gaps: 117/486 - (24%)

  Fly   104 TSDRIANSVLNFANILGQHLANG---KTQIYSPLSIVHSLALLLLGAKGRSYEELSTVFDI---- 161
            |.|.:..:...|...|.|.:...   |...:||||:..:|.::.|||:..|..::..|...
Human    12 TMDSLVTANTKFCFDLFQEIGKDDRHKNIFFSPLSLSAALGMVRLGARSDSAHQIDEVLHFNEFS 76

  Fly   162 ------PD----------------------TSRLHEQ--------------FGLMLQDLQQPTRE 184
                  ||                      |..|.:|              ||.:|..|.
Human    77 QNESKEPDPCLKSNKQKVLADSSLEGQKKTTEPLDQQAGSLNNESGLVSCYFGQLLSKLD----- 136

  Fly   185 AISAGRPLTDWRASSAMRSNRRAQRPGAHEVHLANGLFTQTGYTLNPDYRRVIVEVYASDLQIQD 249
                 |..||:..|                  :||.|:.:..:.:..:|...:::.|.:.::..|
Human   137 -----RIKTDYTLS------------------IANRLYGEQEFPICQEYLDGVIQFYHTTIESVD 178

  Fly   250 FEGSPATARYNINAYVAQHTKNHIENIIASD-IPQTTRMILANALYFKAFWETDFIESATRPDNF 313
            |:.:|..:|..||.:|...::..|:.:.:.| |...|.::|.||:||||.|||.|....|....|
Human   179 FQKNPEKSRQEINFWVECQSQGKIKELFSKDAINAETVLVLVNAVYFKAKWETYFDHENTVDAPF 243

  Fly   314 YPNGEGTEPVMRVQMMATGGAYPYHEDHELGCKIIGLPY-RGNLSTMYIIQP--FKSSVRELMAL 375
            ..|....:   .|:||...|.|......|:..:|:.:.| :|.|| |:::.|  .|.:::.|..|
Human   244 CLNANENK---SVKMMTQKGLYRIGFIEEVKAQILEMRYTKGKLS-MFVLLPSHSKDNLKGLEEL 304

  Fly   376 QKRLTADKIESMIS--RMYRRAALVAFPKMHLTESVNLKTVMQRMGLGGIFSAVQNDLSLIATNE 438
            ::::|.:|:.:..|  .|...:.:::||:..|.:|.:|.:::|.||:..||...:.||:.|:.:
Human   305 ERKITYEKMVAWSSSENMSEESVVLSFPRFTLEDSYDLNSILQDMGITDIFDETRADLTGISPS- 368

  Fly   439 ATRTNALGGNSLQNLEAQRRAGTGGARSDLVVDDIVHKVDFTVNEQGTEAAAS--SVTYLKKSGP 501
                                       .:|.:..|:||....|:|.||:|||:  :|...:....
Human   369 ---------------------------PNLYLSKIIHKTFVEVDENGTQAAAATGAVVSERSLRS 406

  Fly   502 DVLFRGDTPFMVLVRHDPTKLVLFYGLINEP 532
            .|.|..:.||:..:||:.|:.:||||.:..|
Human   407 WVEFNANHPFLFFIRHNKTQTILFYGRVCSP 437

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Spn28Dc	NP_609172.1	SERPIN	111..527	CDD:238101	111/472 (24%)
SERPINB12	XP_005266835.2	ovalbumin_like	16..437	CDD:239014	113/480 (24%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X28
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.910