Protein Alignment Spn28Dc and SERPINH1

DIOPT Version :10

• Sequence 1: NP_609172.1
• Gene: Spn28Dc / 34091
• FlyBaseID: FBgn0031973
• Length: 536
• Species: Drosophila melanogaster
• Sequence 2: NP_001226.2
• Gene: SERPINH1 / 871
• HGNCID: 1546
• Length: 418
• Species: Homo sapiens
• Alignment Length: 193
• Identity: 38/193 - (19%)
• Similarity: 60/193 - (31%)
• Gaps: 82/193 - (42%)

  Fly     1 HAITLLSVSHSQGARKMKNEREPLLGHAADGGSNGSGLDVAEHQRLLARPDLRSSPENMIVDPSN 65
            |:..|:.:..||....:..|.|              |.|::         .|.:|...:::||..
Human   298 HSAELVYILESQRLSVVLQEEE--------------GRDLS---------CLVASLVQVMMDPYF 339

  Fly    66 DT----DSLVSKEDPTYGSSSGEPYEPSMHRTLEHPTTNLDTMIHLLKGNIGTGILAM------- 119
            .|    .|||.||    ...:|.|:              ||...||.:....:.:..:
Human   340 RTITGFQSLVQKE----WVMAGYPF--------------LDRCNHLKRSEKESPLFLLFLDTTWQ 386

  Fly   120 -----PDAFKHAGLY---------VGLFGTLFMGAVCTHCMHMLVNCSHELCRRLQVPSLSFA 168
                 |.||:.:..|         :.||||            .|.|..|:..::    |..||
Human   387 LLEQYPAAFEFSETYLAVLCDSTRISLFGT------------FLFNSPHQRVKQ----STEFA 433

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Spn28Dc	NP_609172.1	serpin28D-like_insects	111..532	CDD:381061	14/79 (18%)
SERPINH1	NP_001226.2	serpinH1_CBP1	36..417	CDD:381003	32/171 (19%)
		Prevents secretion from ER. /evidence=ECO:0000255|PROSITE-ProRule:PRU10138	415..418		2/14 (14%)