DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Spn28Dc and zgc:174259

DIOPT Version :9

Sequence 1:	NP_609172.1	Gene:	Spn28Dc / 34091	FlyBaseID:	FBgn0031973	Length:	536	Species:	Drosophila melanogaster
Sequence 2:	XP_021331992.1	Gene:	zgc:174259 / 791587	ZFINID:	ZDB-GENE-080213-10	Length:	410	Species:	Danio rerio

Alignment Length:	442	Identity:	99/442 - (22%)
Similarity:	167/442 - (37%)	Gaps:	90/442 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly   111 SVLNFANILGQHL---------ANGKTQIYSPLSIVHSLALLLLGAKGRSYEEL-------STVF 159
            |::|..|....||         ...|...:||.|:..:|:.|.|||.|.:.::|       |.:|
Zfish    35 SLINMNNDFAFHLYKRLIESPDYQSKNIFFSPFSVSMALSELSLGAGGDTKQQLLSGIGYSSAIF 99

  Fly   160 DIPDTSRLHEQFGLMLQDLQQPTREAISAGRPLTDWRASSAMRSNRRAQRPGAHEVHLANGLFTQ 224
               .|..:|:.|..:|:|:                            ..|.|. ::.:...|:..
Zfish   100 ---STEEMHQLFHSLLEDI----------------------------GNRTGV-DIDVGTALYAS 132

  Fly   225 TGYTLNPDYRRVIVEVYASDLQIQDFEGSPATARYNINAYVAQHTKNHIENIIASDIPQTTRMIL 289
            ..:..:..:...:.|.|.||....||.......:  ||.||.:.|...| |....|:...|.|:|
Zfish   133 DRFKPHSKFLEDMKEFYHSDGFTVDFSVKETVDQ--INKYVEEKTHGKI-NQAVDDLDADTFMVL 194

  Fly   290 ANALYFKAFWETDFIESATRPDNFYPNGEGTEPVMRVQMMATGGAYPYHEDHELGCKIIGLPYRG 354
            ...:|||..|:..|....|....|:.:.:.|.|   ||||........:.|.||..|::.|.|..
Zfish   195 LTYIYFKGKWDKPFNPKTTSESTFHIDDKTTVP---VQMMHQYERLKVYYDAELSTKVLCLDYND 256

  Fly   355 NLSTMYIIQPFKSSVRELMALQKRLTADKIESMISRMYRRAALVAFPKMHLTESVNLKTVMQRMG 419
            :.|....:.......:.:..|:..::...:|.....:..|...:..||:.|..|.:||.:::.||
Zfish   257 SFSMFLAVPDVHMGRKTIKDLEMTVSRQHVEKWRRSVSERKVDIYVPKLSLKTSYSLKDILKGMG 321

  Fly   420 LGGIFSAVQNDLSLIATNEATRTNALGGNSLQNLEAQRRAGTGGARSDLVVDDIVHKVDFTVNEQ 484
            :..:||                              .:...||.:...:.|..::||....::|:
Zfish   322 MADMFS------------------------------DKADFTGVSEEKIYVSKVLHKATLDIDEK 356

  Fly   485 GTEAAASSVTYLK--KSGP--DVLFRGDTPFMVLVRHDPTKLVLFYGLINEP 532
            ||.|||.:..:|:  ...|  |:.|  |.|||:.:.......:||.|.:..|
Zfish   357 GTTAAAVTTVHLRFMSYSPMSDLSF--DRPFMIFITDQTNDNILFVGKVVNP 406

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Spn28Dc	NP_609172.1	SERPIN	111..527	CDD:238101	97/435 (22%)
zgc:174259	XP_021331992.1	alpha-1-antitrypsin_like	39..403	CDD:239011	96/433 (22%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D491891at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11461
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	3.020