Protein Alignment Spn28Dc and SERPING1

DIOPT Version :10

• Sequence 1: NP_609172.1
• Gene: Spn28Dc / 34091
• FlyBaseID: FBgn0031973
• Length: 536
• Species: Drosophila melanogaster
• Sequence 2: NP_000053.2
• Gene: SERPING1 / 710
• HGNCID: 1228
• Length: 500
• Species: Homo sapiens
• Alignment Length: 529
• Identity: 112/529 - (21%)
• Similarity: 192/529 - (36%)
• Gaps: 164/529 - (31%)

  Fly    56 PPAVPLQSPGLVNGLGNQNDPALNRISGTSVKPSNLP-----AAYSNGYVDLATSDRIANSVLNF 115
            |...|...|        ...|.:.....|:..|::.|     .::..|.|.|. ||..::|.
Human    86 PTTQPTTEP--------TTQPTIQPTQPTTQLPTDSPTQPTTGSFCPGPVTLC-SDLESHST--- 138

  Fly   116 ANILGQHLANGKTQIY---------------SPLSIVHSLALLLLGAKGRSYEELSTVFDIP-DT 164
            ..:||..|.:...::|               ||.||...|..:||||...:...|.::...| |.
Human   139 EAVLGDALVDFSLKLYHAFSAMKKVETNMAFSPFSIASLLTQVLLGAGENTKTNLESILSYPKDF 203

  Fly   165 SRLHEQFGLMLQDLQQPTREAISAGRPLTDWRASSAMRSNRRAQRPGAHEVHLANGLFTQTGYTL 229
            :.:|:                              |::.                  ||..|.|
Human   204 TCVHQ------------------------------ALKG------------------FTTKGVT- 219

  Fly   230 NPDYRRVIVEVYAS-DLQIQD---------FEGSPATARYN-------INAYVAQHTKNHIENII 277
                  .:.:::.| ||.|:|         :..||.....|       ||.:||::|.|.|..::
Human   220 ------SVSQIFHSPDLAIRDTFVNASRTLYSSSPRVLSNNSDANLELINTWVAKNTNNKISRLL 278

  Fly   278 ASDIPQTTRMILANALYFKAFWETDFIESATRPDNFYPNGEGTEPVMRVQMMATGGAYP--YHED 340
            .| :|..||::|.||:|..|.|:|.|....||.:.|:....    |::|.|| ....||  :..|
Human   279 DS-LPSDTRLVLLNAIYLSAKWKTTFDPKKTRMEPFHFKNS----VIKVPMM-NSKKYPVAHFID 337

  Fly   341 HELGCKIIGLPYRGNLSTMYII-QPFKSSVREL---------MALQKRLTADKIESMISRMYRRA 395
            ..|..|:..|....|||.:.:: |..|..:.::         .|:.::|...|.:         .
Human   338 QTLKAKVGQLQLSHNLSLVILVPQNLKHRLEDMEQALSPSVFKAIMEKLEMSKFQ---------P 393

  Fly   396 ALVAFPKMHLTESVNLKTVMQRMGLGGIFSAVQNDLSLIATNEATRTNALGGNSLQNLEAQRRAG 460
            .|:..|::.:|.|.::.::|:::.    |.....||:|....|
Human   394 TLLTLPRIKVTTSQDMLSIMEKLE----FFDFSYDLNLCGLTE---------------------- 432

  Fly   461 TGGARSDLVVDDIVHKVDFTVNEQGTEAAASSVTYLKKSGPDVLFRGDTPFMVLVRHDPTKLVLF 525
                ..||.|..:.|:....:.|.|.||||:|...:.::  .::|....||:.::.....|..:|
Human   433 ----DPDLQVSAMQHQTVLELTETGVEAAAASAISVART--LLVFEVQQPFLFVLWDQQHKFPVF 491

  Fly   526 YGLINEPPA 534
            .|.:.:|.|
Human   492 MGRVYDPRA 500

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Spn28Dc	NP_609172.1	serpin28D-like_insects	111..532	CDD:381061	98/465 (21%)
SERPING1	NP_000053.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	20..43
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	65..118		7/39 (18%)
		7 X 4 AA tandem repeats of [QE]-P-T-[TQ]	85..119		7/40 (18%)
		serpinG1_C1-INH	136..496	CDD:381006	98/464 (21%)