DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Spn28Dc and Serpini2

DIOPT Version :9

Sequence 1:	NP_609172.1	Gene:	Spn28Dc / 34091	FlyBaseID:	FBgn0031973	Length:	536	Species:	Drosophila melanogaster
Sequence 2:	NP_080736.2	Gene:	Serpini2 / 67931	MGIID:	1915181	Length:	405	Species:	Mus musculus

Alignment Length:	448	Identity:	102/448 - (22%)
Similarity:	196/448 - (43%)	Gaps:	78/448 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly    95 YSNGYVDLATSDRIANSVLNFANILGQHLANGKTQIYSPLSIVHSLALLLLGAKGRSYEELSTVF 159
            :|......||..:||:..::....:.  |::....|:|||.....|.::.|||||::.:::....
Mouse    13 FSGSQTSRATDQKIADFAVDLYKAIS--LSHKNNIIFSPLGTTMLLGMVQLGAKGKAQQQILKTL 75

  Fly   160 DIPDTSRLHEQFGLMLQDLQQPTREAISAGRPLTDWRASSAMRSNRRAQRPGAHEVHLANGLFTQ 224
            .:..|                |..|..|..:.|     .||:...::     ....:||:.|:.|
Mouse    76 RMRGT----------------PAGEEFSVLKSL-----FSAISKKKQ-----EFTFNLASALYLQ 114

  Fly   225 TGYTLNPDYRRVIVEVYASDLQIQDFEGSPATARYNINAYVAQHTKNHIENIIA-SDIPQTTRMI 288
            .|:.:...|.....|.:.|..::.||..:..:|: .|:.:|...|...|:|:.: .:....||::
Mouse   115 EGFIVKETYLHSNKEFFQSATKLVDFLDAKTSAQ-AISTWVESKTDGKIKNMFSEEEFGPLTRLV 178

  Fly   289 LANALYFKAFWETDFIESATRPDNFYPNGEGT--EPVMRVQMMATGGAYPYHEDHELGCKIIGLP 351
            |.||:|||..|:..|.:..|...:|......|  .|:|:..:.|   .|.|.....:.|:::.||
Mouse   179 LVNAIYFKGDWKQKFRKEDTEMTDFTKKDGSTVKVPMMKALLRA---QYGYFSQSSMTCQVLELP 240

  Fly   352 YRGNLSTMYIIQPFK-SSVRELMALQKRLTADKIESMISRMYRRAALVAFPKMHLTESVNLKTVM 415
            |:.:..::.||.|.: :|:.|   ::.::||..:....|.::.....|:.|:..:.:.::||..:
Mouse   241 YKADEFSLVIILPTEDTSIEE---VENQVTAPHVRRWFSELHEEEVEVSLPRFKIEQKLDLKEAL 302

  Fly   416 QRMGLGGIFSAVQNDLSLIATNEATRTNALGGNSLQNLEAQRRAGTGGARSDLVVDDIVHKVDFT 480
            ..:.:..|||                    ||..|..:...         |::.|..::.||.|.
Mouse   303 YSLNVTEIFS--------------------GGCDLSGITDS---------SEVYVSRVMQKVFFE 338

  Fly   481 VNEQGTEAAASSVTYLKKSGPDVL------FRGDTPFMVLVRHDPTKLVLFYGLINEP 532
            :||.|:|||||:...:    |.::      |..:.||:.:::|..|:.:||.|.:.:|
Mouse   339 INEDGSEAAASTGINI----PAIMSLTQTQFLANHPFLFILKHIRTESILFMGKVTDP 392

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Spn28Dc	NP_609172.1	SERPIN	111..527	CDD:238101	95/425 (22%)
Serpini2	NP_080736.2	neuroserpin	23..405	CDD:239003	99/438 (23%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11461
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X28
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	3.010