Protein Alignment Spn28Dc and SERPINE3

DIOPT Version :9

• Sequence 1: NP_609172.1
• Gene: Spn28Dc / 34091
• FlyBaseID: FBgn0031973
• Length: 536
• Species: Drosophila melanogaster
• Sequence 2: NP_001094790.1
• Gene: SERPINE3 / 647174
• HGNCID: 24774
• Length: 424
• Species: Homo sapiens
• Alignment Length: 442
• Identity: 94/442 - (21%)
• Similarity: 162/442 - (36%)
• Gaps: 102/442 - (23%)

  Fly   115 FANILGQHLA---NGKTQIYSPLSIVHSLALLLLGAKGRSYEELS-----TVFDIPDTSRLHEQF 171
            ||..|.|.:|   |....:.||..:...|.:|..||:|.:.::|:     ||.|......||..:
Human    33 FALHLYQSVAACRNETNFVISPAGVSLPLEILQFGAEGSTGQQLADALGYTVHDKRVKDFLHAVY 97

  Fly   172 GLMLQDLQQPTREAISAGRPLTDWRASSAMRSNRRAQRPGAHEVHLANGLFTQTGYTLNPDYRRV 236
            ..:      ||.   |.|.                       |:.||..||.|.|..|:|.:...
Human    98 ATL------PTS---SQGT-----------------------EMELACSLFVQVGTPLSPCFVEH 130

  Fly   237 IVEVYASDLQIQDFEGSPATARYNINAYVAQHTKNHIENIIASDIPQT--------------TRM 287
            :.....|.|:..|.....:|         |..|........|...|..              .::
Human   131 VSWWANSSLEPADLSEPNST---------AIQTSEGASRETAGGGPSEGPGGWPWEQVSAAFAQL 186

  Fly   288 ILANALYFKAFWETDFIESATRPDNFYPNGEGTEPVMRVQMM--ATGGAYPYHED---HELGCKI 347
            :|.:.:.|:..|...|..:.|:   ..|.......|::|.||  .|...|...:|   |::|  :
Human   187 VLVSTMSFQGTWRKRFSSTDTQ---ILPFTCAYGLVLQVPMMHQTTEVNYGQFQDTAGHQVG--V 246

  Fly   348 IGLPYRGNLSTMYIIQPFKSSVRELMALQKRLTADKIESMISRMYRRAALVAFPKMHLTESVNLK 412
            :.|||.|:..:::::.| :.....|..::..|||..|....:.:.|....|..|:..:....|||
Human   247 LELPYLGSAVSLFLVLP-RDKDTPLSHIEPHLTASTIHLWTTSLRRARMDVFLPRFRIQNQFNLK 310

  Fly   413 TVMQRMGLGGIFSAVQNDLSLIATNEATRTNALGGNSLQNLEAQRRAGTGGARSDLVVDDIVHKV 477
            :::...|:..:|..::.:|.                           |..| :....|.:.:||.
Human   311 SILNSWGVTDLFDPLKANLK---------------------------GISG-QDGFYVSEAIHKA 347

  Fly   478 DFTVNEQGTEAAASSVTYLKKSGPDVLFRGDTPFMVLVRHDPTKLVLFYGLI 529
            ...|.|:||:|:.::...|.|.....:|:.|.||:..:|...|.:.:|:..|
Human   348 KIEVLEEGTKASGATALLLLKRSRIPIFKADRPFIYFLREPNTGITVFFDRI 399

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Spn28Dc	NP_609172.1	SERPIN	111..527	CDD:238101	93/438 (21%)
SERPINE3	NP_001094790.1	SERPIN	31..399	CDD:238101	93/440 (21%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	143..174		6/39 (15%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11461
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	2.010