Protein Alignment Spn28Dc and SERPINB3

DIOPT Version :9

• Sequence 1: NP_609172.1
• Gene: Spn28Dc / 34091
• FlyBaseID: FBgn0031973
• Length: 536
• Species: Drosophila melanogaster
• Sequence 2: NP_008850.1
• Gene: SERPINB3 / 6317
• HGNCID: 10569
• Length: 390
• Species: Homo sapiens
• Alignment Length: 424
• Identity: 111/424 - (26%)
• Similarity: 189/424 - (44%)
• Gaps: 84/424 - (19%)

  Fly   131 YSPLSIVHSLALLLLGAKGRSYEELSTV--FD--------------IPDTSRLHEQFGLMLQDLQ 179
            |||:||..:|.::|||||..:.:::..|  ||              :..:..:|.||..:|.:..
Human    29 YSPISITSALGMVLLGAKDNTAQQIKKVLHFDQVTENTTGKAATYHVDRSGNVHHQFQKLLTEFN 93

  Fly   180 QPTREAISAGRPLTDWRASSAMRSNRRAQRPGAHEVHLANGLFTQTGYTLNPDYRRVIVEVYASD 244
            :.|                            .|:|:.:||.||.:..|....:|...|.:.|.:.
Human    94 KST----------------------------DAYELKIANKLFGEKTYLFLQEYLDAIKKFYQTS 130

  Fly   245 LQIQDFEGSPATARYNINAYVAQHTKNHIENII-ASDIPQTTRMILANALYFKAFWETDFIESAT 308
            ::..||..:|..:|..||::|...|...|:|:| ..:|...|.::|.||:|||..||..|.:..|
Human   131 VESVDFANAPEESRKKINSWVESQTNEKIKNLIPEGNIGSNTTLVLVNAIYFKGQWEKKFNKEDT 195

  Fly   309 RPDNFYPNGEGTEPVMRVQMMATGGAYPYHEDHELGCKIIGLPYRGNLSTMYIIQPFKSSVRELM 373
            :.:.|:||   ......:|||....::.:....::..|::.:||:|...:|.::.|  :.:..|.
Human   196 KEEKFWPN---KNTYKSIQMMRQYTSFHFASLEDVQAKVLEIPYKGKDLSMIVLLP--NEIDGLQ 255

  Fly   374 ALQKRLTADKIESMISRMYRRAALV--AFPKMHLTESVNLKTVMQRMGLGGIFSAVQNDLSLIAT 436
            .|:::|||:|:....|....|...|  ..|:..:.||.:||..::.||:..||:. ..|||
Human   256 KLEEKLTAEKLMEWTSLQNMRETRVDLHLPRFKVEESYDLKDTLRTMGMVDIFNG-DADLS---- 315

  Fly   437 NEATRTNALGGNSLQNLEAQRRAGTGGARSDLVVDDIVHKVDFTVNEQGTEAAASSVTYLKKSGP 501
                                   |..|:|. ||:..::||....|.|:|.||||::......|.|
Human   316 -----------------------GMTGSRG-LVLSGVLHKAFVEVTEEGAEAAAATAVVGFGSSP 356

  Fly   502 ---DVLFRGDTPFMVLVRHDPTKLVLFYGLINEP 532
               :..|..:.||:..:|.:.|..:||||..:.|
Human   357 TSTNEEFHCNHPFLFFIRQNKTNSILFYGRFSSP 390

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Spn28Dc	NP_609172.1	SERPIN	111..527	CDD:238101	108/417 (26%)
SERPINB3	NP_008850.1	serpinB3_B4_SCCA1_2	1..390	CDD:381030	110/422 (26%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X28
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.910