DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Spn28Dc and Serpinb2

DIOPT Version :9

Sequence 1:	NP_609172.1	Gene:	Spn28Dc / 34091	FlyBaseID:	FBgn0031973	Length:	536	Species:	Drosophila melanogaster
Sequence 2:	NP_067728.1	Gene:	Serpinb2 / 60325	RGDID:	621823	Length:	416	Species:	Rattus norvegicus

Alignment Length:	458	Identity:	121/458 - (26%)
Similarity:	202/458 - (44%)	Gaps:	80/458 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly   108 IANSVLNFA-NILGQHLANGKTQ--IYSPLSIVHSLALLLLGAKGRSYEELSTV--------FDI 161
            :||::  || |:|.|...:..||  ..||.||..:||::.|||:..:.|:::.|        :|:
  Rat     6 MANTM--FALNLLKQIEQSNSTQNIFISPWSISSTLAIVFLGAQANTEEQMAKVLNFDKIGSYDL 68

  Fly   162 P----------DTSRLHEQFGLMLQDLQQPTREAISAGRPLTDWRASSAMRSNRRAQRPGAHEVH 216
            .          |.::..::....:..||...|:.|.:        |.|::.|.....|.|.:.:.
  Rat    69 TPGNPENFHGCDFAQHIQRDNYPVAILQAQARDKIHS--------AFSSLSSTINTPRLGDYLLE 125

  Fly   217 LANGLFTQTGYTLNPDYRRVIVEVYASDLQIQDFEGSPATARYNINAYVAQHTKNHIENII-ASD 280
            .||.||.:.......:|.:...:.|:::.:..||......||..||::|...||..|.|:: ...
  Rat   126 SANKLFGEKSARFKEEYIQRCKKYYSTEPEAVDFLECANEARKKINSWVKTQTKGEIPNLLPEGS 190

  Fly   281 IPQTTRMILANALYFKAFWETDFIESATRPDNFYP---NGEGTEPVMRVQMMATGGAYPYHEDHE 342
            :.:.|:|:|.|.:|||..|:|.|   ..|.:..||   |...::|   ||||............:
  Rat   191 VDEDTKMVLVNTIYFKGRWKTPF---QKRLNGLYPFRVNLNESKP---VQMMYLREKLNIGYIKD 249

  Fly   343 LGCKIIGLPYRGNLSTMYIIQP--FKSSVRELMALQKRLTADKIESMISR--MYRRAALVAFPKM 403
            |..:|:.|||.||:| |:::.|  .:.|...|..|::.:..|.....||:  :.....||..||.
  Rat   250 LKTQILELPYIGNIS-MFLLLPDEIEDSSTGLEMLEREINFDNFNKWISKETLDEDDVLVYIPKF 313

  Fly   404 HLTESVNLKTVMQRMGLGGIFSAVQNDLSLIATNEATRTNALGGNSLQNLEAQRRAGTGGARSDL 468
            .|.::..||.::||||:...|:..:.|.|              |.|..|              ||
  Rat   314 KLAQNYELKPILQRMGMEDAFNKGKADFS--------------GMSESN--------------DL 350

  Fly   469 VVDDIVHKVDFTVNEQGTEAAASSVTYLK----KSGPDVLFRGDTPFMVLVRHDPTKLVLFYGLI 529
            .:.::.|:....|||:||.||..:...:.    ..||.  |..|.||:..:.::.|:.:||.|..
  Rat   351 FLSEVFHQATVDVNEEGTVAAGGTGAVMTGRTGHGGPQ--FVADHPFLFFIMNNITRTILFVGRF 413

  Fly   530 NEP 532
            :.|
  Rat   414 SSP 416

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Spn28Dc	NP_609172.1	SERPIN	111..527	CDD:238101	117/448 (26%)
Serpinb2	NP_067728.1	serpinB2_PAI-2	2..416	CDD:381029	120/456 (26%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X28
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.910