DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Spn28Dc and serpinb1l2

DIOPT Version :9

Sequence 1:	NP_609172.1	Gene:	Spn28Dc / 34091	FlyBaseID:	FBgn0031973	Length:	536	Species:	Drosophila melanogaster
Sequence 2:	NP_001038636.1	Gene:	serpinb1l2 / 568898	ZFINID:	ZDB-GENE-041001-117	Length:	382	Species:	Danio rerio

Alignment Length:	435	Identity:	119/435 - (27%)
Similarity:	188/435 - (43%)	Gaps:	71/435 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly   109 ANSV--LNFANILGQHLANGKTQIYSPLSIVHSLALLLLGAKGRSYEELSTVFDIPDTSRLHEQF 171
            |||:  |:....|....|.|.. .:|||||..:|:::.|||:|.:..|:..|......|..|..|
Zfish     7 ANSLFALDLYRALSASSAEGNI-FFSPLSISAALSMVYLGARGDTAGEMEKVLCFSSVSDFHAHF 70

  Fly   172 GLMLQDLQQPTREAISAGRPLTDWRASSAMRSNRRAQRPGAHEVHLANGLFTQTGYTLNPDYRRV 236
            ..::..:..|:              ||..:|              |||.|:.:..::..|.|...
Zfish    71 KTLISSINSPS--------------ASYILR--------------LANRLYGEKTFSFLPMYVDS 107

  Fly   237 IVEVYASDLQIQDFEGSPATARYNINAYVAQHTKNHIENIIASD-IPQTTRMILANALYFKAFWE 300
            .:::|.::.|..||..:...:|..||.:|.:.|:|.|::::... :.:.||::|.||:|||..|.
Zfish   108 TMKLYHAEPQTVDFIRAADDSRQFINKWVEKQTENQIKDLLQPGVVNEMTRLLLVNAIYFKGNWM 172

  Fly   301 TDFIESATRPDNFYPNGEGTEPVMRVQMMATGGAYPYHEDHELGCKIIGLPYRGNLSTMYIIQP- 364
            ..|...||:...|..|...:.|   ||||.....:||....|...:::.|||.....:|.|:.|
Zfish   173 HTFDAHATKEMPFKINQNESRP---VQMMDQVENFPYRCIPEYKLQVLELPYTQQELSMLILLPD 234

  Fly   365 -FKSSVRELMALQKRLTADKIESMISRMYR---RAALVAFPKMHLTESVNLKTVMQRMGLGGIFS 425
             .|.....|:.|:..|...|:....||...   |..:|..||..|.....|...:::||:..:|.
Zfish   235 EIKYGSDPLLKLESELNLQKLLDWTSRGKMDTWRKIIVRLPKFKLEIESCLSETLEKMGMSSVFQ 299

  Fly   426 AVQNDLSLIATNEATRTNALGGNSLQNLEAQRRAGTGGARSDLVVDDIVHKVDFTVNEQGTEAAA 490
            ..:.||:.:::|                        ||    |.:..::||....|||:||||||
Zfish   300 ETKADLTGMSSN------------------------GG----LFLSAVIHKAFVEVNEEGTEAAA 336

  Fly   491 SSVTYLKKSGPDVLFR---GDTPFMVLVRHDPTKLVLFYGLINEP 532
            ::...|..|.....|.   .|.|||..:||:||..:||.|....|
Zfish   337 ATALLLPISACQGAFHDFIADHPFMFFIRHNPTNSILFLGRFRAP 381

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Spn28Dc	NP_609172.1	SERPIN	111..527	CDD:238101	115/426 (27%)
serpinb1l2	NP_001038636.1	SERPIN	5..381	CDD:294093	118/433 (27%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11461
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X28
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	3.010