Protein Alignment Spn28Dc and SERPINF2

DIOPT Version :9

• Sequence 1: NP_609172.1
• Gene: Spn28Dc / 34091
• FlyBaseID: FBgn0031973
• Length: 536
• Species: Drosophila melanogaster
• Sequence 2: XP_005256758.2
• Gene: SERPINF2 / 5345
• HGNCID: 9075
• Length: 507
• Species: Homo sapiens
• Alignment Length: 542
• Identity: 125/542 - (23%)
• Similarity: 221/542 - (40%)
• Gaps: 114/542 - (21%)

  Fly     4 LLLALLLVSSVCCESELFRDDLRTP-ETMAYINGLMQRRHQMQQEAQQHIQAIPPAVPLQSPGLV 67
            ||..||::|..|         |:.| ...:.::.:.....|:.....|  :.:.|...|:
Human    19 LLWGLLVLSWSC---------LQGPCSVFSPVSAMEPLGRQLTSGPNQ--EQVSPLTLLK----- 67

  Fly    68 NGLGNQNDPALNRISGTSVKPSNLPAAYSNGYVDLATSDRIANSVLNFANILGQHLANGKT---Q 129
              |||| :|.    ..|::|  :.|...|.......| .|:|.:::.|...|...:|...|   .
Human    68 --LGNQ-EPG----GQTALK--SPPGVCSRDPTPEQT-HRLARAMMAFTADLFSLVAQTSTCPNL 122

  Fly   130 IYSPLSIVHSLALLLLGAKGRSYEELSTVFDIPDTSRLHEQFGLMLQDLQQPTREAISAGRPLTD 194
            |.||||:..:|:.|.|||:..:.:.|..|        ||...|..|..|
Human   123 ILSPLSVALALSHLALGAQNHTLQRLQQV--------LHAGSGPCLPHL---------------- 163

  Fly   195 WRASSAMRSNRRAQRPGAHEVHLANGLFTQTGYTLNPDYRRVIVEVYASDLQIQDFEGSPATARY 259
                    .:|..|..|.....||..::.|.|:.:..|:.....:::.:  :.....|.......
Human   164 --------LSRLCQDLGPGAFRLAARMYLQKGFPIKEDFLEQSEQLFGA--KPVSLTGKQEDDLA 218

  Fly   260 NINAYVAQHTKNHIENIIASDIPQTTRMILANALYFKAFWETDFIESATRPDNFYPNGEGTEPVM 324
            |||.:|.:.|:..|:..: |.:|:.|.::|.||::|:.||...|..|.|:.|:|:.:.:.|.||.
Human   219 NINQWVKEATEGKIQEFL-SGLPEDTVLLLLNAIHFQGFWRNKFDPSLTQRDSFHLDEQFTVPVE 282

  Fly   325 RVQMMATGGAYPYH----EDHELGCKIIGLPYRGNLSTMYIIQP-FKSSVRELMALQKRLTADKI 384
            .:|    ...||..    |..|:  ::...|::.|:|.:.::.. |:.:|.:::|   .|:.|.:
Human   283 MMQ----ARTYPLRWFLLEQPEI--QVAHFPFKNNMSFVVLVPTHFEWNVSQVLA---NLSWDTL 338

  Fly   385 ESMISRMYRRAALVAFPKMHLTESVNLKTVMQRMGLGGIFSAVQNDLSLIATNEATRTNALGGNS 449
            ...:  ::.|...|..||::|...::|...:.::||..:|.|  .||
Human   339 HPPL--VWERPTKVRLPKLYLKHQMDLVATLSQLGLQELFQA--PDL------------------ 381

  Fly   450 LQNLEAQRRAGTGGARSDLVVDDIVHKVDFTVNEQGTEAAASSVTYLKKSGPDVLFRGDTPFMVL 514
                       .|.:...|||..:.|:....::|.|.||||::...:.:.... .|..:.||:..
Human   382 -----------RGISEQSLVVSGVQHQSTLELSEVGVEAAAATSIAMSRMSLS-SFSVNRPFLFF 434

  Fly   515 VRHDPTKLVLFYGLINEP-PAA 535
            :..|.|.|.||.|.:..| |:|
Human   435 IFEDTTGLPLFVGSVRNPNPSA 456

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Spn28Dc	NP_609172.1	SERPIN	111..527	CDD:238101	97/423 (23%)
SERPINF2	XP_005256758.2	alpha2AP	98..449	CDD:239008	99/428 (23%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11461
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	2.010