Protein Alignment Spn28Dc and SERPINI1

DIOPT Version :9

• Sequence 1: NP_609172.1
• Gene: Spn28Dc / 34091
• FlyBaseID: FBgn0031973
• Length: 536
• Species: Drosophila melanogaster
• Sequence 2: NP_001116224.1
• Gene: SERPINI1 / 5274
• HGNCID: 8943
• Length: 410
• Species: Homo sapiens
• Alignment Length: 441
• Identity: 103/441 - (23%)
• Similarity: 200/441 - (45%)
• Gaps: 81/441 - (18%)

  Fly   106 DRIANSVLNFANILGQHLANGKTQ--IYSPLSIVHSLALLLLGAKGRSYEELSTVFDIPDTSRLH 168
            :.||:..:|..|.|   .|.|:.:  ::|||||..::.::.|||:|.:.:|:...... |:.:..
Human    24 EAIADLSVNMYNRL---RATGEDENILFSPLSIALAMGMMELGAQGSTQKEIRHSMGY-DSLKNG 84

  Fly   169 EQFGLMLQDLQQPTREAISAGRPLTDWRASSAMRSNRRAQRPGAHEVHLANGLFTQTGYTLNPDY 233
            |:|..:.:                         .||....:...:.:.:||.||.|.|:.:|.::
Human    85 EEFSFLKE-------------------------FSNMVTAKESQYVMKIANSLFVQNGFHVNEEF 124

  Fly   234 RRVIVEVYASDLQIQDFEGSPATARYNINAYVAQHTKNHIENIIA-SDIPQTTRMILANALYFKA 297
            .:::.:.:.:.:...||..:.|.|.| ||.:|..:|.|.:::::: .|....|.:.|.||:|||.
Human   125 LQMMKKYFNAAVNHVDFSQNVAVANY-INKWVENNTNNLVKDLVSPRDFDAATYLALINAVYFKG 188

  Fly   298 FWETDFIESATRPDNFYPNGEGTEPVMRVQMMATGGAYPYHE----DHELG--CKIIGLPYRGN- 355
            .|::.|....||..:|..:.|..   :::.||...|.:.|.|    .:|.|  .:::.:||.|:
Human   189 NWKSQFRPENTRTFSFTKDDESE---VQIPMMYQQGEFYYGEFSDGSNEAGGIYQVLEIPYEGDE 250

  Fly   356 LSTMYIIQPFKSSVRELMALQKRLTADKIESMISRMYRRAALVAFPKMHLTESVNLKTVMQRMGL 420
            :|.|.::.  :..| .|..|:..:.|..:|...:.:.::...|..|:..:.:.::||.|::.:|:
Human   251 ISMMLVLS--RQEV-PLATLEPLVKAQLVEEWANSVKKQKVEVYLPRFTVEQEIDLKDVLKALGI 312

  Fly   421 GGIFSAVQNDLSLIATNEATRTNALGGNSLQNLEAQRRAGTGGARSDLVVDDIVHKVDFTVNEQG 485
            ..||.   .|.:|...::                          ..::.:...:||....|||:|
Human   313 TEIFI---KDANLTGLSD--------------------------NKEIFLSKAIHKSFLEVNEEG 348

  Fly   486 TEAAASS----VTYLKKSGPDVLFRGDTPFMVLVRHDPTKLVLFYGLINEP 532
            :||||.|    ::.:....|.|:.  |.||..|:|:..|..:||.|.:..|
Human   349 SEAAAVSGMIAISRMAVLYPQVIV--DHPFFFLIRNRRTGTILFMGRVMHP 397

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Spn28Dc	NP_609172.1	SERPIN	111..527	CDD:238101	99/429 (23%)
SERPINI1	NP_001116224.1	neuroserpin	23..410	CDD:239003	103/441 (23%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11461
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X28
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	3.010