Protein Alignment Spn28Dc and SERPINA10

DIOPT Version :9

• Sequence 1: NP_609172.1
• Gene: Spn28Dc / 34091
• FlyBaseID: FBgn0031973
• Length: 536
• Species: Drosophila melanogaster
• Sequence 2: XP_016876842.1
• Gene: SERPINA10 / 51156
• HGNCID: 15996
• Length: 484
• Species: Homo sapiens
• Alignment Length: 543
• Identity: 123/543 - (22%)
• Similarity: 216/543 - (39%)
• Gaps: 109/543 - (20%)

  Fly    22 RDDLRTPETMAYINGLMQRRHQMQQEAQQHIQAIPP---AVPLQSPGLVNGLG----NQNDPA-L 78
            :|.|:..|......|    ||.: ..|..|::.:|.   :|.|....||.||.    :...|| .
Human    16 QDKLQEQEGSLAAEG----RHSL-ASAADHMKVVPSLLLSVLLAQVWLVPGLAPSPQSPETPAPQ 75

  Fly    79 NRISGTSVKP----------SNLPAAYSNGYVDLATSDRIANSVLNFA-----NILGQHLANGKT 128
            |:.|.....|          |...|:.......:|:..::|....||.     .|..:|..|
Human    76 NQTSRVVQAPKEEEEDEQEASEEKASEEEKAWLMASRQQLAKETSNFGFSLLRKISMRHDGN--- 137

  Fly   129 QIYSPLSIVHSLALLLLGAKGRSYEELSTVFDIPDTSRLHEQFGLMLQDLQQPTREAISAGRPLT 193
            .::||..:..::..|:|||.|.:..::..              ||.||.| :||:..:
Human   138 MVFSPFGMSLAMTGLMLGATGPTETQIKR--------------GLHLQAL-KPTKPGL------- 180

  Fly   194 DWRASSAMRSNRRAQRPGAHEVHLANGLFT---------QTGYTLNPDYRRVIVEVYASDLQIQD 249
               ..|..:..|....... |:.|..|.|.         :|.:.|:..|       :.::....:
Human   181 ---LPSLFKGLRETLSRNL-ELGLTQGSFAFIHKDFDVKETFFNLSKRY-------FDTECVPMN 234

  Fly   250 FEGSPATARYNINAYVAQHTKNHIENIIASDIPQTTRMILANALYFKAFWETDFIESATRPDNFY 314
            |..: :.|:..:|.|:.:.|:..|..:. .:|...|::||.:.:.||..|.|.|....|..|.|:
Human   235 FRNA-SQAKRLMNHYINKETRGKIPKLF-DEINPETKLILVDYILFKGKWLTPFDPVFTEVDTFH 297

  Fly   315 PNGEGTEPVMRVQMMATGGAYPYHEDHELGCKIIGLPYRGNLSTMYIIQPFKSSVRELMALQKRL 379
            .:...|   ::|.||...|.:....|....|.::.|||:|| :||.::  ....:.:.:||:..|
Human   298 LDKYKT---IKVPMMYGAGKFASTFDKNFRCHVLKLPYQGN-ATMLVV--LMEKMGDHLALEDYL 356

  Fly   380 TADKIESMISRMYRRAALVAFPKMHLTESVNLKTVMQRMGLGGIFSAVQNDLSLIATNEATRTNA 444
            |.|.:|:.:..|..|...|.|||..|.:...:..::::||:..|||...:...|.||
Human   357 TTDLVETWLRNMKTRNMEVFFPKFKLDQKYEMHELLRQMGIRRIFSPFADLSELSAT-------- 413

  Fly   445 LGGNSLQNLEAQRRAGTGGARSDLVVDDIVHKVDFTVNEQGTEAAASSVTYLKKSGPDVLFRGDT 509
              |.:||                  |..::.:....|:|:||||.|..::.:.......:.:.|.
Human   414 --GRNLQ------------------VSRVLQRTVIEVDERGTEAVAGILSEITAYSMPPVIKVDR 458

  Fly   510 PFMVLVRHDPTKLVLFYGLINEP 532
            ||..::..:.:.::||.|.:..|
Human   459 PFHFMIYEETSGMLLFLGRVVNP 481

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Spn28Dc	NP_609172.1	SERPIN	111..527	CDD:238101	97/429 (23%)
SERPINA10	XP_016876842.1	PZI	114..478	CDD:239010	99/435 (23%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D491891at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.920