DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Spn28Dc and Spn28F

DIOPT Version :9

Sequence 1:	NP_609172.1	Gene:	Spn28Dc / 34091	FlyBaseID:	FBgn0031973	Length:	536	Species:	Drosophila melanogaster
Sequence 2:	NP_524957.2	Gene:	Spn28F / 49807	FlyBaseID:	FBgn0028987	Length:	375	Species:	Drosophila melanogaster

Alignment Length:	452	Identity:	102/452 - (22%)
Similarity:	196/452 - (43%)	Gaps:	97/452 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly    89 SNLPAAYSNGYVDLATSDRIANSVLNFANILGQHLANGKTQIYSPLSIVHSLALLLLGAKGRSYE 153
            :::...:::.:..|...:..||::::                 ||||:..:|::..:||:.::.:
  Fly    11 TSVSCRFADDFYQLLAKENAANNLIS-----------------SPLSVEIALSMAYMGARAKTAQ 58

  Fly   154 ELSTVFDIPDTSR-LHEQFGLMLQDLQQPTREAISAGRPLTDWRASSAMRSNRRAQRPGAHEVHL 217
            |:..|..:||..: :..::..:|..|:  .||.::.                          :.|
  Fly    59 EMRNVLKLPDDKKEVAAKYKDLLSKLE--GREKVAT--------------------------LSL 95

  Fly   218 ANGLFTQTGYTLNPDYRRVIVEVYASDLQIQDFEGSPATARYNINAYVAQHTKNHIENIIASDIP 282
            ||.::....:.|.|.|.:::.:.:.::.:..|.. .|..|...:|.:|...|:..|:::::|:..
  Fly    96 ANRIYVNKKFQLVPSYNQMVKDSFMAEAEAIDIV-DPNKASSIVNNWVDNQTRGKIKDLVSSNDM 159

  Fly   283 QTTRMILANALYFKAFWETDFIESATRPDNFYPNGEGTEPVMRVQMMATGGAYPYHEDHELGCKI 347
            ....:|:.||:|||..||..|....|:..||..:.:.:.|   |:||:...::....|.|||.||
  Fly   160 SKMELIVLNAIYFKGQWEYKFNPKLTKKRNFRVSDQKSVP---VEMMSLFQSFRAAHDSELGAKI 221

  Fly   348 IGLPYRGNLSTMYIIQPFKSSVRELMALQKRLTADKIESMISRMYRRAALVAFPKMHLTESVNLK 412
            |.||||.:..:|.|..|  ..|..|..|:|::...|     .::.:....:..||..:.....|.
  Fly   222 IELPYRNSSLSMLIFLP--DQVDGLSELEKKIVGFK-----PKLSKMDVTLRLPKFKIEFFAQLN 279

  Fly   413 TVMQRMGLGGIF--SAVQNDLSLIATNEATRTNALGGNSLQNLEAQRRAGTGGARSDLVVDDIVH 475
            .|:..||:...|  ||...||                  ::|             |::.|..::|
  Fly   280 KVLVAMGIQDAFEKSADFKDL------------------VEN-------------SNVHVKKVIH 313

  Fly   476 KVDFTVNEQGTE-AAASSVTYLKKSGP----DVLFRGDTPFMVLVRHDPTKLVLFYGLINEP 532
            |....|||:|.| |||:::.:::.|.|    .::|..|.||..::|...|  :.|.|...:|
  Fly   314 KAFIEVNEEGAEAAAATALLFVRYSMPMPSSQMVFNADHPFAYVIRDRET--IYFQGHFVKP 373

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Spn28Dc	NP_609172.1	SERPIN	111..527	CDD:238101	97/423 (23%)
Spn28F	NP_524957.2	SERPIN	14..370	CDD:238101	101/444 (23%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11461
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X28
	3	3.010