Protein Alignment Spn28Dc and SERPINA2

DIOPT Version :9

• Sequence 1: NP_609172.1
• Gene: Spn28Dc / 34091
• FlyBaseID: FBgn0031973
• Length: 536
• Species: Drosophila melanogaster
• Sequence 2: NP_006211.2
• Gene: SERPINA2 / 390502
• HGNCID: 8985
• Length: 421
• Species: Homo sapiens
• Alignment Length: 539
• Identity: 113/539 - (20%)
• Similarity: 210/539 - (38%)
• Gaps: 143/539 - (26%)

  Fly     8 LLLVSSVCC--ESELFRDDLRTPETMAYINGLMQRRHQMQQEAQQHIQAIPPAVPLQSPGLVNGL 70
            :||::.:||  .|.|..|.              |.....:.:...|.|
Human     9 ILLLAGLCCLVPSSLVEDP--------------QEDAAQKTDTSHHDQ----------------- 42

  Fly    71 GNQNDPALNRISGTSVKPSNLPAAYSNGYVDLATSDRIANSVLNFANILGQHLANGKTQIYSPLS 135
            |:..|.|..:||      .|:.....:.|.:||...:.:|.::                  :|.|
Human    43 GDWEDLACQKIS------YNVTDLAFDLYKELADLSQTSNVLV------------------TPTS 83

  Fly   136 IVHSLALLLLGAKGRSYEELSTVFDIPDT----SRLHEQFGLMLQDLQQP-TREAISAGRPLTDW 195
            :..:.|:|.||.|..:..|:....::..|    :::||.|..:||.|.:| ||..::.|
Human    84 VAMAFAMLSLGTKADTRTEILEGLNVNLTETPEAKIHECFQQVLQALSRPDTRLQLTTG------ 142

  Fly   196 RASSAMRSNRRAQRPGAHEVHLANGLFTQTGYTLNPDYRRVIVEVY---ASDLQIQDFEGSPATA 257
                                   :.||......|...:.....::|   ||.:..:|.|    .|
Human   143 -----------------------SSLFVNKSMKLVDTFLEDTKKLYHSEASSINFRDTE----EA 180

  Fly   258 RYNINAYVAQHTKNHIENIIASDIPQTTRMILANALYFKAFWETDFIESATRPDNFYPNGEGTEP 322
            :..||.||.:.|...:.::: ..:.:.|.:.|.:.:.|...|:..|.......:.|:.:   .:.
Human   181 KEQINNYVEKRTGRKVVDLV-KHLKKDTSLALVDYISFHGKWKDKFKAEHIMVEGFHVD---DKT 241

  Fly   323 VMRVQMMATGGAYPYHEDHELGCKIIGLPYRGNLSTMYIIQPFKSSVRELMALQKRLTADKIESM 387
            ::||.|:...|.:..|.|.||...::...|.||.:..:|:    ...:::..|:::||...:|::
Human   242 IIRVPMINHLGRFDIHRDRELSSWVLAQHYVGNATAFFIL----PDPKKMWQLEEKLTYSHLENI 302

  Fly   388 ISRMYRRAALVAFPKMHLTESVNLKTVMQRMGLGGIFSAVQNDLSLIATNEATRTNALGGNSLQN 452
            ......|:..:.|||:.::.:..||.|::.:|:..|||           |||.    |.|.|.:
Human   303 QRAFDIRSINLHFPKLSISGTYKLKRVLRNLGITKIFS-----------NEAD----LSGVSQE- 351

  Fly   453 LEAQRRAGTGGARSDLVVDDIVHKVDFTVNEQGTEAAASSVTYLKKSG----PDVLFRGDTPFMV 513
                         :.|.:...||....|::|:|||  |:...:|::..    ..|:|  :.||:|
Human   352 -------------APLKLSKAVHVAVLTIDEKGTE--ATGAPHLEEKAWSKYQTVMF--NRPFLV 399

  Fly   514 LVRHDPTKLVLFYGLINEP 532
            :::.|.|...||.|.:..|
Human   400 IIKDDITNFPLFIGKVVNP 418

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Spn28Dc	NP_609172.1	SERPIN	111..527	CDD:238101	91/427 (21%)
SERPINA2	NP_006211.2	SERPIN	62..418	CDD:214513	96/447 (21%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D491891at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11461
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X28
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	4	4.020