DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Spn28Dc and Spn47C

DIOPT Version :9

Sequence 1:	NP_609172.1	Gene:	Spn28Dc / 34091	FlyBaseID:	FBgn0031973	Length:	536	Species:	Drosophila melanogaster
Sequence 2:	NP_001163116.1	Gene:	Spn47C / 36163	FlyBaseID:	FBgn0033574	Length:	382	Species:	Drosophila melanogaster

Alignment Length:	440	Identity:	99/440 - (22%)
Similarity:	187/440 - (42%)	Gaps:	75/440 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly   104 TSDRIANSVLNFANILGQHLANGK----TQIYSPLSIVHSLALLLLGAKGRSYEELST--VFDIP 162
            |:..::.|.:.||..|.:.| |.:    ..:.||.....::.|:.:||.|:|.:||.:  :..:.
  Fly     7 TAPSLSASPIVFARNLFRAL-NDEVPPVNMMVSPAGARSAMTLVFMGAGGKSADELRSKLILGVS 70

  Fly   163 DTSRLHEQFGLMLQDLQQPTREAISAGRPLTDWRASSAMRSNRRAQRPGAHEVHLANGLFTQTGY 227
            :.|.:.:|......|.....::.::                           :.|...|:.....
  Fly    71 NKSEVAKQHAESWTDECSCAKKGVA---------------------------LRLVTRLYVNEEE 108

  Fly   228 TLNPDYRRVIVEVYASDLQIQDFEGSPATARYNINAYVAQHTKNHIENIIASDI-PQTTRMILAN 291
            .:..|:..:.:|.:.::....::. :|..:...:|.::.:||...:.|:...:: ...:.:||.|
  Fly   109 KIRTDFNDMALEFFNAEAYSLNYL-NPEDSVKKVNKWLEKHTFYTVRNLFTPEVFNSDSSVILVN 172

  Fly   292 ALYFKAFWETDFIESATRPDNFYPNGEGTEPVMRVQMMATGGAYPYHEDHELGCKIIGLPY-RGN 355
            :|:|:|.|...|.:..|:.|:|:.|   ....|.|.||...|.:.|.|..:|..:|:.||: |.|
  Fly   173 SLFFRAKWNKIFPQQLTQIDDFWIN---PRQRMEVSMMRQIGQFRYGESKKLKSQILQLPFERSN 234

  Fly   356 LSTMYIIQPFKSSVRELMALQKRLTADKIESMISRMYRRAALVAFPKMHLTESVNLKTVMQRMGL 420
            | ||.||.|  :::..|..|:::|....:..:.::...:...|..||..:..:|:||..:|:||:
  Fly   235 L-TMMIILP--TAIDGLPELEEKLGQLDMNEVAAKSLMKEVDVTIPKFRIECTVDLKVPLQKMGI 296

  Fly   421 GGIFSAVQNDLSLIATNEATRTNALGGNSLQNLEAQRRAGTGGARSDLVVDDIVHKVDFTVNEQG 485
            ..:|.|.|.|||                .|..::..::           :.:..|||...|.|.|
  Fly   297 NSVFDAGQADLS----------------DLFEMKTPQK-----------ISEARHKVFLNVTEFG 334

  Fly   486 TEAAASSVT---YLKKSGPDVLFRGDTPFMVLVRHDPTKLVLFYGLINEP 532
            .|.|..:..   .|||:.....|:.|.||:..:|  ..|.|.|.|...:|
  Fly   335 CEVAPEAEVQPEVLKKNPDRKFFKADRPFVFAIR--DRKNVYFVGHFVKP 382

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Spn28Dc	NP_609172.1	SERPIN	111..527	CDD:238101	96/426 (23%)
Spn47C	NP_001163116.1	SERPIN	18..379	CDD:238101	96/424 (23%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11461
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X28
	3	3.010