DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Spn28Dc and Spn42De

DIOPT Version :9

Sequence 1:	NP_609172.1	Gene:	Spn28Dc / 34091	FlyBaseID:	FBgn0031973	Length:	536	Species:	Drosophila melanogaster
Sequence 2:	NP_610246.3	Gene:	Spn42De / 35602	FlyBaseID:	FBgn0033115	Length:	404	Species:	Drosophila melanogaster

Alignment Length:	436	Identity:	111/436 - (25%)
Similarity:	192/436 - (44%)	Gaps:	86/436 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly   115 FANILGQHLA---NGKTQIYSPLSIVHSLALLLLGAKGRSYEELSTVFDIPDTSRLHEQFGLMLQ 176
            ||:.|...||   :|:..::||.||...|||..|||:|.:.:||              :.||.|:
  Fly    35 FASQLFGQLAKSQSGRNIVFSPSSIRTGLALAYLGAEGSTADEL--------------KLGLGLE 85

  Fly   177 -----DLQQPTREAISAGRPLTDWRASSAMRSNRRAQRPGAHEV---HLANGLFTQTGYTLNPDY 233
                 ::.:...:.::.|:    |..:|           |..:|   ..||.:|....:.|...|
  Fly    86 GAGKTEVAEKLDQLLAKGQ----WEKAS-----------GDEDVPKLKYANRIFVTQRFKLTQTY 135

  Fly   234 RRVIVEVYASDLQIQDFEGSPATARYNINAYVAQHTKNHIENIIASD-IPQTTRMILANALYFKA 297
            :.::.:.:|:..:..:|.....||:: ||::|.:.|...|:::||.: :...|..||.||:||||
  Fly   136 QDLVSKNFAAAAENVNFTQKADTAKH-INSWVEEQTHQQIKDLIAPESLDADTSAILVNAIYFKA 199

  Fly   298 FWETDFIESATRPDNFYPNGEGTEPVMRVQMMATGGAYPYHEDHELGCKIIGLPYRGNLSTMYII 362
            .|::.|.:.||...:|..:| |.:  :.|..|:....:.:.|..||..|::.|||.|......||
  Fly   200 DWQSSFPDYATYASDFVNHG-GRK--VSVDTMSQEDYFRFGELTELKAKVVELPYTGTDIVFLII 261

  Fly   363 QPFKSSVRELMALQKRLTADKIESMISRMYRRAALVAFPKMHLTESVNLKTVMQRMGLGGIFSAV 427
            .|  ...:.|..::::|....:..:.|::.||...|..||......|.|:..::.:|:..:||..
  Fly   262 LP--QEEQGLAIVEEKLMGIDLNEISSQLRRRKVRVQLPKFKFEFDVPLQAALEELGIKKLFSPG 324

  Fly   428 QNDLSLIATNEATRTNALGGNSLQNLEAQRRAGTGGARSDLVVDDIVHKVDFTVNEQGTEAAASS 492
            .|..||...:|..|                            :.::.||....|||:||  .||.
  Fly   325 ANLSSLYQGSEPLR----------------------------ISEVKHKAIIEVNEKGT--TASG 359

  Fly   493 VTYLKKS------GPDVL-FRGDTPFMVLVRHDPTKLVLFYGLINE 531
            .|::|.|      |.:|. |..|.||...::  ..:..||.|.:::
  Fly   360 ATFIKVSVESLTIGEEVFEFIADHPFFFAIK--DAQNTLFLGHVSQ 403

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Spn28Dc	NP_609172.1	SERPIN	111..527	CDD:238101	110/430 (26%)
Spn42De	NP_610246.3	SERPIN	31..401	CDD:238101	111/432 (26%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11461
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X28
	3	3.010