DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Spn28Dc and Serpinb1b

DIOPT Version :9

Sequence 1:	NP_609172.1	Gene:	Spn28Dc / 34091	FlyBaseID:	FBgn0031973	Length:	536	Species:	Drosophila melanogaster
Sequence 2:	XP_038952280.1	Gene:	Serpinb1b / 306891	RGDID:	1560658	Length:	380	Species:	Rattus norvegicus

Alignment Length:	434	Identity:	121/434 - (27%)
Similarity:	198/434 - (45%)	Gaps:	70/434 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly   109 ANSV--LNFANILGQHLANGKTQIYSPLSIVHSLALLLLGAKGRSYEELSTVFDIPDTSRLHEQF 171
            |||:  |...:.|.:....|  .|:||.||..:||::.|||||.|         .|.:.||.|.|
  Rat     7 ANSLFALELFHTLSESSPTG--NIFSPFSISSALAMVFLGAKGSS---------APSSLRLAETF 60

  Fly   172 GL-MLQDLQQPTREAISAGRPLTDWRASSAMRSNRRAQRPGA-HEVHLANGLFTQTGYTLNPDYR 234
            .. .::|:.                  |.....|...::.|| |.:.:||.|:.:..|...|::.
  Rat    61 HFDSVEDIH------------------SRFQSLNAEMRKHGASHTLKVANRLYGEKTYNFLPEFL 107

  Fly   235 RVIVEVYASDLQIQDFEGSPATARYNINAYVAQHTKNHIENIIASD-IPQTTRMILANALYFKAF 298
            ....::|.:||...||:.:...||..||.:|...|:..|..::|.. :..||:::|.||:|||..
  Rat   108 ASTQKMYGADLAPVDFQHASEDARKEINKWVKGQTEGKIPELLAGGVVNSTTKLVLVNAIYFKGI 172

  Fly   299 WETDFIESATRPDNFYPNGEGTEPVMRVQMMATGGAYPYHEDHELGCKIIGLPYRGNLSTMYIIQ 363
            |:..|:...|....|..|.:.|:   .|:||.....:|:....:|.||::.:||:|...:|.|:.
  Rat   173 WQEKFLTRHTTDAPFRLNKKDTK---MVKMMYQKEKFPFGYIPDLKCKVLEMPYQGGELSMVILL 234

  Fly   364 P--FKSSVRELMALQKRLTADKIESMI--SRMYRRAALVAFPKMHLTESVNLKTVMQRMGLGGIF 424
            |  .:.....|..::::||.:|:....  ..:......|..||..:.||..|.:.:.|:||..:|
  Rat   235 PEDIEDESTGLQKIEEQLTLEKLYEWTKHENLKEIDVHVNLPKFKIEESYILNSNLGRLGLQDLF 299

  Fly   425 SAVQNDLSLIATNEATRTNALGGNSLQNLEAQRRAGTGGARSDLVVDDIVHKVDFTVNEQGTEAA 489
            |:.:.|||                           |...:| |:.:..||||....|||:|||||
  Rat   300 SSSKADLS---------------------------GMSESR-DIFISKIVHKSFVEVNEEGTEAA 336

  Fly   490 ASSVTYLKKSGPDV-LFRGDTPFMVLVRHDPTKLVLFYGLINEP 532
            |::...::.....: .|..|.||:..:||:||..:||:|.:..|
  Rat   337 AATAGLVEYCLVSIEAFIVDHPFLFFIRHNPTANMLFFGRVCSP 380

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Spn28Dc	NP_609172.1	SERPIN	111..527	CDD:238101	117/425 (28%)
Serpinb1b	XP_038952280.1	serpinB1_LEI	1..380	CDD:381028	120/432 (28%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11461
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X28
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	4.010