DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Spn28Dc and LOC299282

DIOPT Version :9

Sequence 1:	NP_609172.1	Gene:	Spn28Dc / 34091	FlyBaseID:	FBgn0031973	Length:	536	Species:	Drosophila melanogaster
Sequence 2:	NP_001376144.2	Gene:	LOC299282 / 299282	RGDID:	3745	Length:	413	Species:	Rattus norvegicus

Alignment Length:	436	Identity:	120/436 - (27%)
Similarity:	199/436 - (45%)	Gaps:	79/436 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly   108 IANSVLNFANILGQHLA---NGKTQIYSPLSIVHSLALLLLGAKGRSYEEL--STVFDIPDTS-- 165
            :|:|..:||..|.:.||   ..|..::|||||..:|.:|.||||..:.||:  ...|::.:.:
  Rat    45 LASSNTDFALSLYKKLALRNPDKNVVFSPLSISAALTILSLGAKDSTMEEILEGLKFNLTEITEE 109

  Fly   166 RLHEQFGLMLQDLQQPTREAISAGRPLTDWRASSAMRSNRRAQRPGAHEVHLANGLFTQTGYTLN 230
            .:|:.||.:||.|.||..:.                            |::..:.||......:.
  Rat   110 EIHQGFGHLLQRLSQPEDQV----------------------------EINTGSALFIDKEQPIL 146

  Fly   231 PDYRRVIVEVYASDLQIQDFEGSPATARYNINAYVAQHTKNHIENIIASDIPQTTRMILANALYF 295
            .:::.....:|.::..|.||: .|..|:..||.||:..|:..|..:. ||:.:.|.|:|.|.|.|
  Rat   147 SEFQEKTRALYQAEAFIADFK-QPNEAKKLINDYVSNQTQGKIAELF-SDLEERTSMVLVNYLLF 209

  Fly   296 KAFWETDFIESATRPDNFYPNGEGT--EPVMRVQMMATGGAYPYHEDHELGCKIIGLPYRGNLST 358
            |..|:..|..:.|....||.:.:.:  .|:|:::.:.|    ||..|.||.|.::.|.|.||.|.
  Rat   210 KGKWKVPFNPNDTFESEFYLDEKRSVKVPMMKIKEVTT----PYVRDEELSCSVLELKYTGNASA 270

  Fly   359 MYIIQPFKSSVREL-MALQKRLTADKIESMISRMYRRAALVAFPKMHLTESVNLKTVMQRMGLGG 422
            ::|: |.:..:::: .:||........:|:|.|:...   :..||..::...:||.|:..:|:..
  Rat   271 LFIL-PDQGKMQQVESSLQPETLKKWKDSLIPRIIND---LRMPKFSISTDYSLKEVLPELGIKK 331

  Fly   423 IFSAVQNDLSLIATNEATRTNALGGNSLQNLEAQRRAGTGGARSDLVVDDIVHKVDFTVNEQGTE 487
            :||. |.|||                        |..||    .||.|..:|||....|:|.|||
  Rat   332 VFSQ-QADLS------------------------RITGT----KDLYVSQVVHKAVLDVDETGTE 367

  Fly   488 A-AASSVTYLKKSGPDVLFRGDTPFMVLVRHDPTKLVLFYGLINEP 532
            | ||:.|..:.:..|..| ..:.||||::....::.:||...|..|
  Rat   368 ATAATGVATVIRRQPRTL-NFNRPFMVVITDMDSQSILFVAKITNP 412

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Spn28Dc	NP_609172.1	SERPIN	111..527	CDD:238101	117/426 (27%)
LOC299282	NP_001376144.2	serpinA3_A1AC	36..413	CDD:381019	120/436 (28%)
LOC299282	NP_001376144.2	RCL	365..389		9/24 (38%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D491891at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11461
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	3.020