DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Spn28Dc and Serpina6

DIOPT Version :9

Sequence 1:	NP_609172.1	Gene:	Spn28Dc / 34091	FlyBaseID:	FBgn0031973	Length:	536	Species:	Drosophila melanogaster
Sequence 2:	NP_001009663.1	Gene:	Serpina6 / 299270	RGDID:	1595901	Length:	396	Species:	Rattus norvegicus

Alignment Length:	428	Identity:	96/428 - (22%)
Similarity:	178/428 - (41%)	Gaps:	85/428 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly    96 SNGYVDLATSDRIANSVLNFANILGQHLA---NGKTQIYSPLSIVHSLALLLLG-AKGRSYEELS 156
            ||.:..||.::      ::||..|.|.|.   ..|..:.||:||..:||::.|| |:.:|.:.|.
  Rat    28 SNSHRGLAPTN------VDFAFNLYQRLVALNPDKNTLISPVSISMALAMVSLGSAQTQSLQSLG 86

  Fly   157 TVFDIPDTS--RLHEQFGLMLQDLQQPTREAISAGRPLTDWRASSAMRSNRRAQRPGAHEVHLAN 219
              |::.:||  .:|:.|..:...|:|                :.:.:            |:::.|
  Rat    87 --FNLTETSEAEIHQSFQYLNYLLKQ----------------SDTGL------------EMNMGN 121

  Fly   220 GLFTQTGYTLNPDYRRVIVEVYASDLQIQDFEGSPATARYNINAYVAQHTKNHIENIIASDIPQT 284
            .:|......|...:...:.:.|.|:....||| ....|...||.:|...|:..||::. ||:...
  Rat   122 AMFLLQKLKLKDSFLADVKQYYESEALAIDFE-DWTKASQQINQHVKDKTQGKIEHVF-SDLDSP 184

  Fly   285 TRMILANALYFKAFWETDFIESATRPDNFYPNGEGTEPVMRVQMMATGGAYPYHEDHELGCKIIG 349
            ...||.|.::.:..||..|....||.::||.|...|   ::|.||...|:..|..|....|::|.
  Rat   185 ASFILVNYIFLRGIWELPFSPENTREEDFYVNETST---VKVPMMVQSGSIGYFRDSVFPCQLIQ 246

  Fly   350 LPYRGNLSTMYIIQPFKSSVRELMALQKRLTADKIESMISRMYRRAALVAFPKMHLTESVNLKTV 414
            :.|.|| .|.:.|.|.:..:..::|...|.|.|:...:   |..|...:..||..::::.:||.:
  Rat   247 MDYVGN-GTAFFILPDQGQMDTVIAALSRDTIDRWGKL---MTPRQVNLYIPKFSISDTYDLKDM 307

  Fly   415 MQRMGLGGIFSAVQNDLSLIATNEATRTNALGGNSLQNLEAQRRAGTGGARSDLVVDDIVHKVDF 479
            ::.:.:..:.:. |:|.|                             |..:...:...:|||...
  Rat   308 LEDLNIKDLLTN-QSDFS-----------------------------GNTKDVPLTLTMVHKAML 342

  Fly   480 TVNEQGT--EAAASSVTYLKKSGPDVLFRGDTPFMVLV 515
            .::|...  .:...:..:|:....|:.|  :.||::|:
  Rat   343 QLDEGNVLPNSTNGAPLHLRSEPLDIKF--NKPFILLL 378

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Spn28Dc	NP_609172.1	SERPIN	111..527	CDD:238101	92/413 (22%)
Serpina6	NP_001009663.1	alpha-1-antitrypsin_like	37..392	CDD:239011	92/419 (22%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11461
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	2.100