Protein Alignment Spn28Dc and SERPINA11

DIOPT Version :9

• Sequence 1: NP_609172.1
• Gene: Spn28Dc / 34091
• FlyBaseID: FBgn0031973
• Length: 536
• Species: Drosophila melanogaster
• Sequence 2: NP_001073920.1
• Gene: SERPINA11 / 256394
• HGNCID: 19193
• Length: 422
• Species: Homo sapiens
• Alignment Length: 552
• Identity: 124/552 - (22%)
• Similarity: 211/552 - (38%)
• Gaps: 154/552 - (27%)

  Fly     2 WRLLLALLLVSSVCCESELFRDDLRTPETMAYINGLMQRRHQMQQEAQQHIQAIPPAVPLQSPGL 66
            |..||...:::||.|:..|...|       ..:.|....|||:.:.|
Human     5 WLWLLGTGILASVHCQPLLAHGD-------KSLQGPQPPRHQLSEPA------------------ 44

  Fly    67 VNGLGNQNDPALNRISGTSVKPSNLPAAYSNGYVDLATSDRIANSVLNFANILGQHLANGK--TQ 129
                     ||.:||:.|                           :.|||..|.:.||...  ..
Human    45 ---------PAYHRITPT---------------------------ITNFALRLYKELAADAPGNI 73

  Fly   130 IYSPLSIVHSLALLLLGAKGRS----YEELSTVFDIPDT--SRLHEQFGLMLQDLQQPTREAISA 188
            .:||:||..:||||.|||:..:    .|.|.  |::.:|  :.:|:.|..:|..|..|:.:.
Human    74 FFSPVSISTTLALLSLGAQANTSALILEGLG--FNLTETPEADIHQGFRSLLHTLALPSPKL--- 133

  Fly   189 GRPLTDWRASSAMRSNRRAQRPGAHEVHLANGLFTQTGYTLNPDYRRVIVEVYASDLQIQDFEGS 253
                                     |:.:.|.||..........|...|.|:|.:.....:|..|
Human   134 -------------------------ELKVGNSLFLDKRLKPRQHYLDSIKELYGAFAFSANFTDS 173

  Fly   254 PATARYNINAYVAQHTKNHIENIIASDIPQTTRMILANALYFKAFWETDFIESATRPDNFYPNGE 318
            ..|.| .||.|:.:.|...:.:.: .:..|.|.|:|||.::|||.|:..|....|:....:...|
Human   174 VTTGR-QINDYLRRQTYGQVVDCL-PEFSQDTFMVLANYIFFKAKWKHPFSRYQTQKQESFFVDE 236

  Fly   319 GTEPVMRVQMMATGGAYPYHEDHELGCKIIGLPYRGNLSTMYIIQPFKSSVRELMALQKRLTADK 383
            .|.  ::|.||.....:.:..|.:|.|.::.:.||||...:.:: |....::::.|..:..|..|
Human   237 RTS--LQVPMMHQKEMHRFLYDQDLACTVLQIEYRGNALALLVL-PDPGKMKQVEAALQPQTLRK 298

  Fly   384 -----IESMISRMYRRAALVAFPKMHLTESVNLKTVMQRMGLGGIFSAVQNDLSLIATNEATRTN 443
                 :.|::.        :..|:..::.:.||:.::.::||                     ||
Human   299 WGQLLLPSLLD--------LHLPRFSISGTYNLEDILPQIGL---------------------TN 334

  Fly   444 ALGGNSLQNLEAQRRAGTGGARSDLVVDDIVHKVDFTVNEQGTEAAASS------VTYLKKSGPD 502
            .|      ||||.....||  :.:..:..:.||....::|:||||.|:|      .:....|.|.
Human   335 IL------NLEADFSGVTG--QLNKTISKVSHKAMVDMSEKGTEAGAASGLLSQPPSLNTMSDPH 391

  Fly   503 VLFRGDTPFMVLVRHDPTKLVLFYGLINEPPA 534
            ..|  :.||::|:....|:.:||.|.:..|.|
Human   392 AHF--NRPFLLLLWEVTTQSLLFLGKVVNPVA 421

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Spn28Dc	NP_609172.1	SERPIN	111..527	CDD:238101	103/434 (24%)
SERPINA11	NP_001073920.1	alpha-1-antitrypsin_like	53..416	CDD:239011	105/463 (23%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D491891at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11461
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X28
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	4	4.020