DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Spn28Dc and Serpina3n

DIOPT Version :9

Sequence 1:	NP_609172.1	Gene:	Spn28Dc / 34091	FlyBaseID:	FBgn0031973	Length:	536	Species:	Drosophila melanogaster
Sequence 2:	NP_113719.3	Gene:	Serpina3n / 24795	RGDID:	3747	Length:	418	Species:	Rattus norvegicus

Alignment Length:	444	Identity:	127/444 - (28%)
Similarity:	204/444 - (45%)	Gaps:	92/444 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly   108 IANSVLNFANILGQHLA---NGKTQIYSPLSIVHSLALLLLGAKGRSYEEL--STVFDIPDT--S 165
            :|:...:||..|.:.||   ..|..::|||||..:||::.|||||.|.||:  ...|::.:|  :
  Rat    47 LASINTDFAFSLYKKLALRNPDKNVVFSPLSISAALAVVSLGAKGNSMEEILEGLKFNLTETPET 111

  Fly   166 RLHEQFGLMLQDLQQPTRE-AISAGRPLTDWRASSAMRSNRRAQRPGAHEVHLANGLFTQTGYTL 229
            .:|..||.:||.|.||..| .||.|                             |.||.:....:
  Rat   112 EIHRGFGHLLQRLSQPRDEIQISTG-----------------------------NALFIEKRLQV 147

  Fly   230 NPDYRRVIVEVYASDLQIQDFEGSPATARYNINAYVAQHTKNHIENIIASDIPQTTRMILANALY 294
            ..:::.....:|.::....||:.| ..|:..||.||::.|:..|:.:| :::.:.|.|:|.|.:|
  Rat   148 LAEFQEKAKALYQAEAFTADFQQS-REAKKLINDYVSKQTQGKIQGLI-TNLAKKTSMVLVNYIY 210

  Fly   295 FKAFWETDFIESATRPDNFYPNGEGTE---PVMRVQMMATGGAYPYHEDHELGCKIIGLPYRGNL 356
            ||..|:..|....|....|| :|:...   |:|:::.:.|    ||..|.||.|.::.|.|.||.
  Rat   211 FKGKWKVPFDPRDTFQSEFY-SGKRRPVKVPMMKLEDLTT----PYVRDEELNCTVVELKYTGNA 270

  Fly   357 STMYIIQPFKSSVRELMA-LQK---RLTADKIE-SMISRMYRRAALVAFPKMHLTESVNLKTVMQ 416
            |.::|: |.:..::::.| ||.   |...|.:. |||..:|       .||..::...||:.|:.
  Rat   271 SALFIL-PDQGKMQQVEASLQPETLRRWKDSLRPSMIDELY-------LPKFSISADYNLEDVLP 327

  Fly   417 RMGLGGIFSAVQNDLSLIATNEATRTNALGGNSLQNLEAQRRAGTGGARSDLVVDDIVHKVDFTV 481
            .:|:..:|| .|.|||.|                          ||.  .||:|..:|||....|
  Rat   328 ELGIKEVFS-TQADLSGI--------------------------TGD--KDLMVSQVVHKAVLDV 363

  Fly   482 NEQGTEAAASS-VTYLKKSG--PDVLFRGDTPFMVLVRHDPTKLVLFYGLINEP 532
            .|.||||||:: |.::..|.  ..::...|.||::::....|.:..|...|..|
  Rat   364 AETGTEAAAATGVKFVPMSAKLDPLIIAFDRPFLMIISDTETAIAPFLAKIFNP 417

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Spn28Dc	NP_609172.1	SERPIN	111..527	CDD:238101	124/434 (29%)
Serpina3n	NP_113719.3	serpinA3_A1AC	37..418	CDD:381019	127/444 (29%)
Serpina3n	NP_113719.3	RCL	367..394		8/26 (31%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D491891at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11461
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	3.020