DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Spn28Dc and Serpinb9d

DIOPT Version :9

Sequence 1:	NP_609172.1	Gene:	Spn28Dc / 34091	FlyBaseID:	FBgn0031973	Length:	536	Species:	Drosophila melanogaster
Sequence 2:	NP_035590.1	Gene:	Serpinb9d / 20726	MGIID:	894667	Length:	377	Species:	Mus musculus

Alignment Length:	446	Identity:	114/446 - (25%)
Similarity:	192/446 - (43%)	Gaps:	100/446 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly   117 NILGQHLANGKTQI----------------YSPLSIVHSLALLLLGAKGRSYEELSTVFDIPDTS 165
            |.|.|  |||...|                :||:||..:||::||||||.:..::.....:....
Mouse     2 NTLSQ--ANGTFAIHLLKVLCQDNPSENVCFSPMSISSALAMVLLGAKGNTVTQICQALHLNPDE 64

  Fly   166 RLHEQFGLMLQDLQQPTREAISAGRPLTDWRASSAMRSNRRAQRPGAHEVHLANGLFTQTGYTLN 230
            .:|:.|.|:|.:|.:|..:...    ||                       :||.||.:....|.
Mouse    65 DVHQGFQLLLHNLNKPNNQKYC----LT-----------------------MANRLFVENTCELL 102

  Fly   231 PDYRRVIVEVYASDLQIQDFEGSPATARYNINAYVAQHTKNHIENIIASD-IPQTTRMILANALY 294
            |.::...::.|.|:::...|..:...:|.:||.:|::.|...|.:::..| |...||:|||||||
Mouse   103 PTFKESCLKFYHSEMEQLSFAEAAEESRQHINMWVSKQTNGKIPDLLPKDSIDSQTRLILANALY 167

  Fly   295 FKAFWETDFIESATRPDNFYPNGEGTEPVMRVQMMATGGAYPYHEDH-------ELGCKIIGLPY 352
            |:..|...|.:.:|:...|..|.:.|.|   ||||       :.||.       |:..:::.:||
Mouse   168 FQGTWYKLFEKDSTKEMPFKINKKETRP---VQMM-------WQEDRFYHAYVKEIQAQVLVMPY 222

  Fly   353 RGNLSTMYIIQPFKSSVRELMALQKRLTADKIESMISRMYRRA--ALVAFPKMHLTESVNLKTVM 415
            .|...:..::.|.|..  ::..::..||.:|:.:.....:...  ..|..||..|.|..::.:::
Mouse   223 EGIDLSFVVLLPDKGV--DISKVENNLTFEKLTAWTKPDFMNGIELHVYLPKFQLQEDYDMNSLL 285

  Fly   416 QRMGLGGIFSAVQNDLSLIATNEATRTNALGGNSLQNLEAQRRAGTGGARSDLVVDDIVHKVDFT 480
            |.:|:..:|...:.|||.::|.|                            :|.:.:.|||....
Mouse   286 QHLGILDVFDGSKADLSGMSTKE----------------------------NLCLSNFVHKCVVE 322

  Fly   481 VNEQGTEAAAS----SVTYLKKSGPDVLFRGDTPFMVLVRHDPTKLVLFYGLINEP 532
            |||:||||||:    ::.....|.|.. |..|.||:..:.|..|..:||.|..:.|
Mouse   323 VNEEGTEAAAATAGKTIQCCLGSYPQT-FCADHPFLFFIMHSTTNSILFCGRFSSP 377

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Spn28Dc	NP_609172.1	SERPIN	111..527	CDD:238101	112/439 (26%)
Serpinb9d	NP_035590.1	serpin	1..377	CDD:393296	113/444 (25%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X28
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.910