DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Spn28Dc and Serpina3k

DIOPT Version :9

Sequence 1:	NP_609172.1	Gene:	Spn28Dc / 34091	FlyBaseID:	FBgn0031973	Length:	536	Species:	Drosophila melanogaster
Sequence 2:	NP_035588.2	Gene:	Serpina3k / 20714	MGIID:	98377	Length:	418	Species:	Mus musculus

Alignment Length:	456	Identity:	119/456 - (26%)
Similarity:	206/456 - (45%)	Gaps:	100/456 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly   101 DLATSD---RIANSVLNFANILGQHLA---NGKTQIYSPLSIVHSLALLLLGAKGRSYEEL--ST 157
            |..|.|   .:|:...:||..|.:.||   ..|..::|||||..:|||:.|||||::.||:  ..
Mouse    38 DNGTQDDSLTLASVNTDFAFSLYKKLALKNQDKNIVFSPLSISAALALVSLGAKGKTMEEILEGL 102

  Fly   158 VFDIPDT--SRLHEQFGLMLQDLQQPTREAISAGRPLTDWRASSAMRSNRRAQRPGAHEVHLANG 220
            .|::.:|  :.:|:.||.:||.|.||..:                            .::::.|.
Mouse   103 KFNLTETPEADIHQGFGNLLQSLSQPEDQ----------------------------DQINIGNA 139

  Fly   221 LFTQTGYTLNPDYRRVIVEVYASDLQIQDFEGSPATARYNINAYVAQHTKNHIENIIASDIPQTT 285
            :|.:....:..::......:|.::....||: .|..|:..||.||:..|:..|:.:| |::...|
Mouse   140 MFIEKDLQILAEFHEKTRALYQTEAFTADFQ-QPTEAKNLINDYVSNQTQGMIKKLI-SELDDGT 202

  Fly   286 RMILANALYFKAFWETDFIESATRPDNFYPNGEGT--EPVMRVQMMATGGAYPYHEDHELGCKII 348
            .|:|.|.:|||..|:..|....|....||.:.:.:  .|:|:::::..    .:..|.||.|.::
Mouse   203 LMVLVNYIYFKGKWKISFDPQDTFESEFYLDEKRSVKVPMMKMKLLTA----RHFRDEELSCSVL 263

  Fly   349 GLPYRGNLSTMYII------QPFKSSVR--ELMALQKRLTADKIESMISRMYRRAALVAFPKMHL 405
            .|.|.||.|.:.|:      |..::|::  .|...:|.|.:.:||.:           ..||..:
Mouse   264 ELKYTGNASALLILPDQGRMQQVEASLQPETLRKWRKTLFSSQIEEL-----------NLPKFSI 317

  Fly   406 TESVNL-KTVMQRMGLGGIFSAVQNDLSLIATNEATRTNALGGNSLQNLEAQRRAGTGGARSDLV 469
            .....| :.|:..||:..:|:. |.|||.|.                  ||::          |.
Mouse   318 ASDYRLEEDVLPEMGIKEVFTE-QADLSGIT------------------EAKK----------LS 353

  Fly   470 VDDIVHKVDFTVNEQGTEAAASS--VTYLKKSG-PDVLFRGDTPFMVLVRHDPTKLVLFYGLINE 531
            |..:|||....|.|.||||||::  :..::|:. |.|.|  :.||::::.|...:.:||...:|.
Mouse   354 VSQVVHKAVLDVAETGTEAAAATGVIGGIRKAVLPAVCF--NRPFLIVIYHTSAQSILFMAKVNN 416

  Fly   532 P 532
            |
Mouse   417 P 417

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Spn28Dc	NP_609172.1	SERPIN	111..527	CDD:238101	113/436 (26%)
Serpina3k	NP_035588.2	SERPIN	57..417	CDD:214513	112/435 (26%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D491891at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11461
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X28
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	4.020