Protein Alignment Wwox and CBR3

DIOPT Version :9

• Sequence 1: NP_001285735.1
• Gene: Wwox / 34090
• FlyBaseID: FBgn0031972
• Length: 409
• Species: Drosophila melanogaster
• Sequence 2: NP_001227.1
• Gene: CBR3 / 874
• HGNCID: 1549
• Length: 277
• Species: Homo sapiens
• Alignment Length: 289
• Identity: 60/289 - (20%)
• Similarity: 113/289 - (39%)
• Gaps: 72/289 - (24%)

  Fly   106 SCSTALQVLHGKDLHGRTALITGANCGIGYETARSLAHH-GCEIIFACRNRSSAEAAIERIAQER 169
            |||             |.||:||||.|||...||.|... ..:::...|:.:..:||::::..|.
Human     3 SCS-------------RVALVTGANRGIGLAIARELCRQFSGDVVLTARDVARGQAAVQQLQAEG 54

  Fly   170 PAARSRCRFAALDLSSLRSVQRFVEEIKQSVSHIDYLILNAGVF-----ALPYTRTVDGLETTFQ 229
            .:.    ||..||:..|:|::...:.:::....::.|:.||.|.     .:|:....   |.|.:
Human    55 LSP----RFHQLDIDDLQSIRALRDFLRKEYGGLNVLVNNAAVAFKSDDPMPFDIKA---EMTLK 112

  Fly   230 VSHLSHFYLTLQLETLFDYKTRIIVLSS-------------ESHRFANLPVENLAVHHLSPPPEK 281
            .:..:...:..:|..:.....|::.:||             ...||.:   |.|....|....:|
Human   113 TNFFATRNMCNELLPIMKPHGRVVNISSLQCLRAFENCSEDLQERFHS---ETLTEGDLVDLMKK 174

  Fly   282 Y-------------WSMMAYNNAKL----CNVLFAQELAQRWKQRGISVFSLHPGNMVSSDLSRN 329
            :             |....|..:||    .:.:.|:.|.::.|...|.|.:..|| .|.:|:..
Human   175 FVEDTKNEVHEREGWPNSPYGVSKLGVTVLSRILARRLDEKRKADRILVNACCPG-PVKTDMDG- 237

  Fly   330 YWFYRLLFAIVRPFTKSLQQAAATSIYCA 358
                       :...:::::.|.|.:|.|
Human   238 -----------KDSIRTVEEGAETPVYLA 255

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Wwox	NP_001285735.1	WW	13..43	CDD:197736
		WW	54..86	CDD:197736
		PRK06196	104..402	CDD:235736	60/289 (21%)
		human_WWOX_like_SDR_c-like	121..402	CDD:187669	57/274 (21%)
CBR3	NP_001227.1	carb_red_PTCR-like_SDR_c	6..277	CDD:187585	57/273 (21%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1208
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.900