Protein Alignment Wwox and YKL107W

DIOPT Version :9

• Sequence 1: NP_001285735.1
• Gene: Wwox / 34090
• FlyBaseID: FBgn0031972
• Length: 409
• Species: Drosophila melanogaster
• Sequence 2: NP_012815.1
• Gene: YKL107W / 853753
• SGDID: S000001590
• Length: 309
• Species: Saccharomyces cerevisiae
• Alignment Length: 312
• Identity: 68/312 - (21%)
• Similarity: 107/312 - (34%)
• Gaps: 84/312 - (26%)

  Fly   126 ITGANCGIGYETARSLAHHGCEIIFACRNRSSAEAAIERIAQERPAARSRCRFAALDLSSLRSVQ 190
            |.|...|:|...:|.||.....:....:.....:            .:.:..|...|||
Yeast    28 IIGGTGGLGRAISRELAQRNARVTVVGQTFRDED------------LKDKINFVKADLS------ 74

  Fly   191 RFVEEIKQSVSHID--------YLILNAGVFALPYTR-TVDGLETTFQVSHLSHFYLTLQLETLF 246
             .|.|.|: :||.|        :||...|:||....: |.:|||....||:||.:.:      ..
Yeast    75 -LVSECKR-ISHSDEIPYEELTHLIFTTGIFASRQRQATSEGLEKDMAVSYLSRYII------FH 131

  Fly   247 DYKTRIIVLSSESHRFANLPVENLA----------VHHLSPPPEKYWSMMAYNNAKLCNVLFAQE 301
            |...|:.:..::..   :||...:|          ...|:...:||.:...:.|....|.....:
Yeast   132 DVAKRLGISRTKKD---DLPKVFIAGFPGNGQVGDPDDLNSDEKKYSAYATHMNTVAANESLVID 193

  Fly   302 LAQRWKQRGISVFSLHPG--------NMVSSD--LSR-NYWFYRLLFAIVRPFTKSLQQAAATSI 355
            ...|:  ..|..|.|:||        |::.||  ||| ..|       |:....:|.:..|.|..
Yeast   194 AKDRY--TNIDTFGLNPGLIKTNIRNNLLGSDTYLSRITEW-------IISWTCQSAETYAKTIC 249

  Fly   356 YCATANELTGLSGLYFNNC----------------FFCEPSKLSKSAALQQQ 391
            ....:..:...||..|:|.                .|.|.|:|....||:.|
Yeast   250 TLIASPAIESRSGTMFSNKGDAILPSPGLTKDVVEKFMENSELLVEKALRNQ 301

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Wwox	NP_001285735.1	WW	13..43	CDD:197736
		WW	54..86	CDD:197736
		PRK06196	104..402	CDD:235736	68/312 (22%)
		human_WWOX_like_SDR_c-like	121..402	CDD:187669	68/312 (22%)
YKL107W	NP_012815.1	NADB_Rossmann	26..285	CDD:419666	61/294 (21%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1208
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24320
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.910